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Nicole Dobbs
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Journal Articles

The STING pathway drives noninflammatory neurodegeneration in NGLY1 deficiency

In Special Collection:
Cytokines Collection 2025 , Neuroscience Collection 2025 , Pattern Recognition Receptors and Beyond
Kun Yang, Gustavo Torres-Ramirez, Nicole Dobbs, Jie Han, Makoto Asahina, Reiko Fujinawa, Kun Song, Yun Liu, Weichun Lin, Angelica Oviedo, Chuo Chen, Lei Zhu, William F. Mueller, Kevin Lee, Tadashi Suzuki, Nan Yan
Journal: Journal of Experimental Medicine
J Exp Med (2025) 222 (10): e20242296.
https://doi.org/10.1084/jem.20242296
Published: 11 July 2025
View article titled, The STING pathway drives noninflammatory neurodegeneration in NGLY1 deficiency
Open the PDF for The STING pathway drives noninflammatory neurodegeneration in NGLY1 deficiency in another window
Includes: Supplementary data
Journal Articles

PARP7 inhibits type I interferon signaling to prevent autoimmunity and lung disease

In Special Collection:
JEM Immunology Collection 2025 , JEM Clinical Immunology Collection 2025
Devon Jeltema, Kennady Knox, Nicole Dobbs, Zhen Tang, Cong Xing, Antonina Araskiewicz, Kun Yang, Ivan Rodriguez Siordia, Jason Matthews, Michael Cohen, Nan Yan
Journal: Journal of Experimental Medicine
J Exp Med (2025) 222 (5): e20241184.
https://doi.org/10.1084/jem.20241184
Published: 19 February 2025
View article titled, PARP7 inhibits type I interferon signaling to prevent autoimmunity and lung disease
Open the PDF for PARP7 inhibits type I interferon signaling to prevent autoimmunity and lung disease in another window
Includes: Supplementary data
Journal Articles

STING-mediated disruption of calcium homeostasis chronically activates ER stress and primes T cell death

Jianjun Wu, Yu-Ju Chen, Nicole Dobbs, Tomomi Sakai, Jen Liou, Jonathan J. Miner, Nan Yan
Journal: Journal of Experimental Medicine
J Exp Med (2019) 216 (4): 867–883.
https://doi.org/10.1084/jem.20182192
Published: 18 March 2019
View article titled, STING-mediated disruption of calcium homeostasis chronically activates ER stress and primes T cell death
Open the PDF for STING-mediated disruption of calcium homeostasis chronically activates ER stress and primes T cell death in another window
Includes: Supplementary data