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Journal Articles

The phospholipid kinase PIKFYVE is essential for Th17 differentiation

Douglas S. Prado, Richard T. Cattley, Andreza B. Sonego, Parth Sutariya, Shuxian Wu, Mijoon Lee, William C. Boggess, Mark J. Shlomchik, William F. Hawse

J Exp Med (2024) 222 (2): e20240625.

https://doi.org/10.1084/jem.20240625

Published: 31 December 2024

View article titled, The phospholipid kinase PIKFYVE is essential for Th17 differentiation

Includes: Supplementary data

Journal Articles

B cell–intrinsic Myd88 regulates disease progression in murine lupus

Jeremy S. Tilstra, Minjung Kim, Rachael A. Gordon, Claire Leibler, Haylee A. Cosgrove, Sheldon Bastacky, Kevin M. Nickerson, Mark J. Shlomchik

J Exp Med (2023) 220 (12): e20230263.

https://doi.org/10.1084/jem.20230263

Published: 03 October 2023

View article titled, B cell–intrinsic <em>Myd88</em> regulates disease progression in murine lupus

Journal Articles

Age-associated B cells are heterogeneous and dynamic drivers of autoimmunity in mice

In Special Collection:

Autoimmunity: From Novel Mechanisms to Treatments , B cells, Infectious Diseases, and Autoimmunity , B Cell Biology in Health and Diseases

Kevin M. Nickerson, Shuchi Smita, Kenneth B. Hoehn, Anthony D. Marinov, Kayla B. Thomas, Justin T. Kos, Yi Yang, Sheldon I. Bastacky, Corey T. Watson, Steven H. Kleinstein, Mark J. Shlomchik

J Exp Med (2023) 220 (5): e20221346.

https://doi.org/10.1084/jem.20221346

Published: 24 February 2023

View article titled, Age-associated B cells are heterogeneous and dynamic drivers of autoimmunity in mice

Includes: Supplementary data

Journal Articles

Continuous inhibitory signaling by both SHP-1 and SHIP-1 pathways is required to maintain unresponsiveness of anergic B cells

Andrew Getahun, Nicole A. Beavers, Sandy R. Larson, Mark J. Shlomchik, John C. Cambier

J Exp Med (2016) 213 (5): 751–769.

https://doi.org/10.1084/jem.20150537

Published: 25 April 2016

View article titled, Continuous inhibitory signaling by both SHP-1 and SHIP-1 pathways is required to maintain unresponsiveness of anergic B cells

Journal Articles

IRF4 controls the positioning of mature B cells in the lymphoid microenvironments by regulating NOTCH2 expression and activity

Giorgia Simonetti, Amanda Carette, Kathryn Silva, Haowei Wang, Nilushi S. De Silva, Nicole Heise, Christian W. Siebel, Mark J. Shlomchik, Ulf Klein

J Exp Med (2013) 210 (13): 2887–2902.

https://doi.org/10.1084/jem.20131026

Published: 09 December 2013

View article titled, IRF4 controls the positioning of mature B cells in the lymphoid microenvironments by regulating NOTCH2 expression and activity

Includes: Supplementary data

Journal Articles

MHC class II–dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodies

Nicolas Molnarfi, Ulf Schulze-Topphoff, Martin S. Weber, Juan C. Patarroyo, Thomas Prod’homme, Michel Varrin-Doyer, Aparna Shetty, Christopher Linington, Anthony J. Slavin, Juan Hidalgo, Dieter E. Jenne, Hartmut Wekerle, Raymond A. Sobel, Claude C.A. Bernard, Mark J. Shlomchik, Scott S. Zamvil

J Exp Med (2013) 210 (13): 2921–2937.

https://doi.org/10.1084/jem.20130699

Published: 09 December 2013

View article titled, MHC class II–dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodies

Journal Articles

Autocrine/paracrine TGFβ1 is required for the development of epidermal Langerhans cells

Daniel H. Kaplan, Ming O. Li, Matthew C. Jenison, Warren D. Shlomchik, Richard A. Flavell, Mark J. Shlomchik

J Exp Med (2007) 204 (11): 2545–2552.

https://doi.org/10.1084/jem.20071401

Published: 15 October 2007

View article titled, Autocrine/paracrine TGFβ1 is required for the development of epidermal Langerhans cells

Includes: Supplementary data

Journal Articles

New markers for murine memory B cells that define mutated and unmutated subsets

Shannon M. Anderson, Mary M. Tomayko, Anupama Ahuja, Ann M. Haberman, Mark J. Shlomchik

J Exp Med (2007) 204 (9): 2103–2114.

https://doi.org/10.1084/jem.20062571

Published: 13 August 2007

View article titled, New markers for murine memory B cells that define mutated and unmutated subsets

Includes: Supplementary data

Journal Articles

RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement

Christina M. Lau, Courtney Broughton, Abigail S. Tabor, Shizuo Akira, Richard A. Flavell, Mark J. Mamula, Sean R. Christensen, Mark J. Shlomchik, Gregory A. Viglianti, Ian R. Rifkin, Ann Marshak-Rothstein

J Exp Med (2005) 202 (9): 1171–1177.

https://doi.org/10.1084/jem.20050630

Published: 31 October 2005

View article titled, RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement

Journal Articles

Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus

Sean R. Christensen, Michael Kashgarian, Lena Alexopoulou, Richard A. Flavell, Shizuo Akira, Mark J. Shlomchik

J Exp Med (2005) 202 (2): 321–331.

https://doi.org/10.1084/jem.20050338

Published: 18 July 2005

View article titled, Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus

Includes: Supplementary data

Journal Articles

The Role of Innate Immunity in Autoimmunity

Jean-François Bach, Albert Bendelac, Michael B. Brenner, Harvey Cantor, Gennaro De Libero, Mitchell Kronenberg, Lewis L. Lanier, David H. Raulet, Mark J. Shlomchik, Matthias G. von Herrath

J Exp Med (2004) 200 (12): 1527–1531.

https://doi.org/10.1084/jem.20042110

Published: 20 December 2004

View article titled, The Role of Innate Immunity in Autoimmunity

Journal Articles

The B Cell Receptor Itself Can Activate Complement to Provide the Complement Receptor 1/2 Ligand Required to Enhance B Cell Immune Responses In Vivo

Joerg Rossbacher, Mark J. Shlomchik

J Exp Med (2003) 198 (4): 591–602.

https://doi.org/10.1084/jem.20022042

Published: 18 August 2003

View article titled, The B Cell Receptor Itself Can Activate Complement to Provide the Complement Receptor 1/2 Ligand Required to Enhance B Cell Immune Responses In Vivo

Journal Articles

Very Low Affinity B Cells Form Germinal Centers, Become Memory B Cells, and Participate in Secondary Immune Responses When Higher Affinity Competition Is Reduced

Joseph M. Dal Porto, Ann M. Haberman, Garnett Kelsoe, Mark J. Shlomchik

J Exp Med (2002) 195 (9): 1215–1221.

https://doi.org/10.1084/jem.20011550

Published: 06 May 2002

View article titled, Very Low Affinity B Cells Form Germinal Centers, Become Memory B Cells, and Participate in Secondary Immune Responses When Higher Affinity Competition Is Reduced

Includes: Supplementary data

Journal Articles

Germinal Center Initiation, Variable Gene Region Hypermutation, and Mutant B Cell Selection without Detectable Immune Complexes on Follicular Dendritic Cells

Lynn G. Hannum, Ann M. Haberman, Shannon M. Anderson, Mark J. Shlomchik

J Exp Med (2000) 192 (7): 931–942.

https://doi.org/10.1084/jem.192.7.931

Published: 25 September 2000

View article titled, Germinal Center Initiation, Variable Gene Region Hypermutation, and Mutant B Cell Selection without Detectable Immune Complexes on Follicular Dendritic Cells

Journal Articles

Internalization of Leishmania mexicana Complex Amastigotes via the Fc Receptor Is Required to Sustain Infection in Murine Cutaneous Leishmaniasis

Peter E. Kima, Stephanie L. Constant, Lynn Hannum, Maria Colmenares, Karen S. Lee, Ann M. Haberman, Mark J. Shlomchik, Diane McMahon-Pratt

J Exp Med (2000) 191 (6): 1063–1068.

https://doi.org/10.1084/jem.191.6.1063

Published: 20 March 2000

View article titled, Internalization of <em>Leishmania mexicana</em> Complex Amastigotes via the Fc Receptor Is Required to Sustain Infection in Murine Cutaneous Leishmaniasis

Journal Articles

Autoantigen-Specific B Cell Activation in FAS-Deficient Rheumatoid Factor Immunoglobulin Transgenic Mice

Haowei Wang, Mark J. Shlomchik

J Exp Med (1999) 190 (5): 639–650.

https://doi.org/10.1084/jem.190.5.639

Published: 06 September 1999

View article titled, Autoantigen-Specific B Cell Activation in FAS-Deficient Rheumatoid Factor Immunoglobulin Transgenic Mice

Journal Articles

A Novel Mouse with B Cells but Lacking Serum Antibody Reveals an Antibody-independent Role for B Cells in Murine Lupus

Owen T.M. Chan, Lynn G. Hannum, Ann M. Haberman, Michael P. Madaio, Mark J. Shlomchik

J Exp Med (1999) 189 (10): 1639–1648.

https://doi.org/10.1084/jem.189.10.1639

Published: 17 May 1999

View article titled, A Novel Mouse with B Cells but Lacking Serum Antibody Reveals an Antibody-independent Role for B Cells in Murine Lupus

NARROW

The phospholipid kinase PIKFYVE is essential for Th17 differentiation

B cell–intrinsic Myd88 regulates disease progression in murine lupus

Age-associated B cells are heterogeneous and dynamic drivers of autoimmunity in mice

Continuous inhibitory signaling by both SHP-1 and SHIP-1 pathways is required to maintain unresponsiveness of anergic B cells

IRF4 controls the positioning of mature B cells in the lymphoid microenvironments by regulating NOTCH2 expression and activity

MHC class II–dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodies

Autocrine/paracrine TGFβ1 is required for the development of epidermal Langerhans cells

New markers for murine memory B cells that define mutated and unmutated subsets

RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement

Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus

The Role of Innate Immunity in Autoimmunity

The B Cell Receptor Itself Can Activate Complement to Provide the Complement Receptor 1/2 Ligand Required to Enhance B Cell Immune Responses In Vivo

Very Low Affinity B Cells Form Germinal Centers, Become Memory B Cells, and Participate in Secondary Immune Responses When Higher Affinity Competition Is Reduced

Germinal Center Initiation, Variable Gene Region Hypermutation, and Mutant B Cell Selection without Detectable Immune Complexes on Follicular Dendritic Cells

Internalization of Leishmania mexicana Complex Amastigotes via the Fc Receptor Is Required to Sustain Infection in Murine Cutaneous Leishmaniasis

Autoantigen-Specific B Cell Activation in FAS-Deficient Rheumatoid Factor Immunoglobulin Transgenic Mice

A Novel Mouse with B Cells but Lacking Serum Antibody Reveals an Antibody-independent Role for B Cells in Murine Lupus

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