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Lorraine A. O'Reilly
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Journal Articles

NFκB1 is essential to prevent the development of multiorgan autoimmunity by limiting IL-6 production in follicular B cells

Elisha de Valle, George Grigoriadis, Lorraine A. O’Reilly, Simon N. Willis, Mhairi J. Maxwell, Lynn M. Corcoran, Evelyn Tsantikos, Jasper K.S. Cornish, Kirsten A. Fairfax, Ajithkumar Vasanthakumar, Mark A. Febbraio, Margaret L. Hibbs, Marc Pellegrini, Ashish Banerjee, Philip D. Hodgkin, Axel Kallies, Fabienne Mackay, Andreas Strasser, Steve Gerondakis, Raffi Gugasyan
Journal: Journal of Experimental Medicine
J Exp Med (2016) 213 (4): 621–641.
https://doi.org/10.1084/jem.20151182
Published: 28 March 2016
View article titled, NFκB1 is essential to prevent the development of multiorgan autoimmunity by limiting IL-6 production in follicular B cells
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Includes: Supplementary data
Journal Articles

Megakaryocytes possess a functional intrinsic apoptosis pathway that must be restrained to survive and produce platelets

Emma C. Josefsson, Chloé James, Katya J. Henley, Marlyse A. Debrincat, Kelly L. Rogers, Mark R. Dowling, Michael J. White, Elizabeth A. Kruse, Rachael M. Lane, Sarah Ellis, Paquita Nurden, Kylie D. Mason, Lorraine A. O’Reilly, Andrew W. Roberts, Donald Metcalf, David C.S. Huang, Benjamin T. Kile
Journal: Journal of Experimental Medicine
J Exp Med (2011) 208 (10): 2017–2031.
https://doi.org/10.1084/jem.20110750
Published: 12 September 2011
View article titled, Megakaryocytes possess a functional intrinsic apoptosis pathway that must be restrained to survive and produce platelets
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Includes: Supplementary data
Journal Articles

Destruction of tumor vasculature and abated tumor growth upon VEGF blockade is driven by proapoptotic protein Bim in endothelial cells

Edwina Naik, Lorraine A. O'Reilly, Marie-Liesse Asselin-Labat, Delphine Merino, Ann Lin, Michele Cook, Leigh Coultas, Philippe Bouillet, Jerry M. Adams, Andreas Strasser
Journal: Journal of Experimental Medicine
J Exp Med (2011) 208 (7): 1351–1358.
https://doi.org/10.1084/jem.20100951
Published: 06 June 2011
View article titled, Destruction of tumor vasculature and abated tumor growth upon VEGF blockade is driven by proapoptotic protein Bim in endothelial cells
Open the PDF for Destruction of tumor vasculature and abated tumor growth upon VEGF blockade is driven by proapoptotic protein Bim in endothelial cells in another window
Includes: Supplementary data
Journal Articles

FAS Ligand, Bcl-2, Granulocyte Colony-Stimulating Factor, and p38 Mitogen-Activated Protein Kinase: Regulators of Distinct Cell Death and Survival Pathways in Granulocytes

Andreas Villunger, Lorraine A. O'Reilly, Nils Holler, Jerry Adams, Andreas Strasser
Journal: Journal of Experimental Medicine
J Exp Med (2000) 192 (5): 647–658.
https://doi.org/10.1084/jem.192.5.647
Published: 28 August 2000
View article titled, FAS Ligand, Bcl-2, Granulocyte Colony-Stimulating Factor, and p38 Mitogen-Activated Protein Kinase: <subtitle>Regulators of Distinct Cell Death and Survival Pathways in Granulocytes</subtitle>
Open the PDF for FAS Ligand, Bcl-2, Granulocyte Colony-Stimulating Factor, and p38 Mitogen-Activated Protein Kinase: <subtitle>Regulators of Distinct Cell Death and Survival Pathways in Granulocytes</subtitle> in another window
Journal Articles

bcl-2 Transgene Expression Inhibits Apoptosis in the Germinal Center and Reveals Differences in the Selection of Memory B Cells and Bone Marrow Antibody-Forming Cells

Kenneth G.C. Smith, Amanda Light, Lorraine A. O'Reilly, Soon-Meng Ang, Andreas Strasser, David Tarlinton
Journal: Journal of Experimental Medicine
J Exp Med (2000) 191 (3): 475–484.
https://doi.org/10.1084/jem.191.3.475
Published: 07 February 2000
View article titled, <em>bcl</em>-2 Transgene Expression Inhibits Apoptosis in the Germinal Center and Reveals Differences in the Selection of Memory B Cells and Bone Marrow Antibody-Forming Cells
Open the PDF for <em>bcl</em>-2 Transgene Expression Inhibits Apoptosis in the Germinal Center and Reveals Differences in the Selection of Memory B Cells and Bone Marrow Antibody-Forming Cells in another window
Journal Articles

B Lymphocytes Differentially Use the Rel and Nuclear Factor κB1 (NF-κB1) Transcription Factors to Regulate Cell Cycle Progression and Apoptosis in Quiescent and Mitogen-activated Cells

Raelene J. Grumont, Ian J. Rourke, Lorraine A. O'Reilly, Andreas Strasser, Kensuke Miyake, William Sha, Steve Gerondakis
Journal: Journal of Experimental Medicine
J Exp Med (1998) 187 (5): 663–674.
https://doi.org/10.1084/jem.187.5.663
Published: 02 March 1998
View article titled, B Lymphocytes Differentially Use the Rel and Nuclear Factor κB1 (NF-κB1) Transcription Factors to Regulate Cell Cycle Progression and Apoptosis in Quiescent and Mitogen-activated Cells
Open the PDF for B Lymphocytes Differentially Use the Rel and Nuclear Factor κB1 (NF-κB1) Transcription Factors to Regulate Cell Cycle Progression and Apoptosis in Quiescent and Mitogen-activated Cells in another window