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Lars Kjer-Nielsen
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Journal Articles

A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells

Sidonia B.G. Eckle, Richard W. Birkinshaw, Lyudmila Kostenko, Alexandra J. Corbett, Hamish E.G. McWilliam, Rangsima Reantragoon, Zhenjun Chen, Nicholas A. Gherardin, Travis Beddoe, Ligong Liu, Onisha Patel, Bronwyn Meehan, David P. Fairlie, Jose A. Villadangos, Dale I. Godfrey, Lars Kjer-Nielsen, James McCluskey, Jamie Rossjohn
Journal: Journal of Experimental Medicine
J Exp Med (2014) 211 (8): 1585–1600.
https://doi.org/10.1084/jem.20140484
Published: 21 July 2014
View article titled, A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells
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Includes: Supplementary data
Journal Articles

Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells

Rangsima Reantragoon, Alexandra J. Corbett, Isaac G. Sakala, Nicholas A. Gherardin, John B. Furness, Zhenjun Chen, Sidonia B.G. Eckle, Adam P. Uldrich, Richard W. Birkinshaw, Onisha Patel, Lyudmila Kostenko, Bronwyn Meehan, Katherine Kedzierska, Ligong Liu, David P. Fairlie, Ted H. Hansen, Dale I. Godfrey, Jamie Rossjohn, James McCluskey, Lars Kjer-Nielsen
Journal: Journal of Experimental Medicine
J Exp Med (2013) 210 (11): 2305–2320.
https://doi.org/10.1084/jem.20130958
Published: 07 October 2013
View article titled, Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells
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Journal Articles

Structural insight into MR1-mediated recognition of the mucosal associated invariant T cell receptor

Rangsima Reantragoon, Lars Kjer-Nielsen, Onisha Patel, Zhenjun Chen, Patricia T. Illing, Mugdha Bhati, Lyudmila Kostenko, Mandvi Bharadwaj, Bronwyn Meehan, Ted H. Hansen, Dale I. Godfrey, Jamie Rossjohn, James McCluskey
Journal: Journal of Experimental Medicine
J Exp Med (2012) 209 (4): 761–774.
https://doi.org/10.1084/jem.20112095
Published: 12 March 2012
View article titled, Structural insight into MR1-mediated recognition of the mucosal associated invariant T cell receptor
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Includes: Supplementary data
Journal Articles

Allelic polymorphism in the T cell receptor and its impact on immune responses

Stephanie Gras, Zhenjun Chen, John J. Miles, Yu Chih Liu, Melissa J. Bell, Lucy C. Sullivan, Lars Kjer-Nielsen, Rebekah M. Brennan, Jacqueline M. Burrows, Michelle A. Neller, Rajiv Khanna, Anthony W. Purcell, Andrew G. Brooks, James McCluskey, Jamie Rossjohn, Scott R. Burrows
Journal: Journal of Experimental Medicine
J Exp Med (2010) 207 (7): 1555–1567.
https://doi.org/10.1084/jem.20100603
Published: 21 June 2010
View article titled, Allelic polymorphism in the T cell receptor and its impact on immune responses
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Includes: Supplementary data
Journal Articles

A minimal binding footprint on CD1d-glycolipid is a basis for selection of the unique human NKT TCR

Kwok S. Wun, Natalie A. Borg, Lars Kjer-Nielsen, Travis Beddoe, Ruide Koh, Stewart K. Richardson, Meena Thakur, Amy R. Howell, James P. Scott-Browne, Laurent Gapin, Dale I. Godfrey, James McCluskey, Jamie Rossjohn
Journal: Journal of Experimental Medicine
J Exp Med (2008) 205 (4): 939–949.
https://doi.org/10.1084/jem.20072141
Published: 31 March 2008
View article titled, A minimal binding footprint on CD1d-glycolipid is a basis for selection of the unique human NKT TCR
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Journal Articles

A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition

Lars Kjer-Nielsen, Natalie A. Borg, Daniel G. Pellicci, Travis Beddoe, Lyudmila Kostenko, Craig S. Clements, Nicholas A. Williamson, Mark J. Smyth, Gurdyal S. Besra, Hugh H. Reid, Mandvi Bharadwaj, Dale I. Godfrey, Jamie Rossjohn, James McCluskey
Journal: Journal of Experimental Medicine
J Exp Med (2006) 203 (3): 661–673.
https://doi.org/10.1084/jem.20051777
Published: 27 February 2006
View article titled, A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition
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Includes: Supplementary data
Journal Articles

The immunogenicity of a viral cytotoxic T cell epitope is controlled by its MHC-bound conformation

Fleur E. Tynan, Diah Elhassen, Anthony W. Purcell, Jacqueline M. Burrows, Natalie A. Borg, John J. Miles, Nicholas A. Williamson, Kate J. Green, Judy Tellam, Lars Kjer-Nielsen, James McCluskey, Jamie Rossjohn, Scott R. Burrows
Journal: Journal of Experimental Medicine
J Exp Med (2005) 202 (9): 1249–1260.
https://doi.org/10.1084/jem.20050864
Published: 07 November 2005
View article titled, The immunogenicity of a viral cytotoxic T cell epitope is controlled by its MHC-bound conformation
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Includes: Supplementary data
Journal Articles

Natural HLA Class I Polymorphism Controls the Pathway of Antigen Presentation and Susceptibility to Viral Evasion

Danielle Zernich, Anthony W. Purcell, Whitney A. Macdonald, Lars Kjer-Nielsen, Lauren K. Ely, Nihay Laham, Tanya Crockford, Nicole A. Mifsud, Mandvi Bharadwaj, Linus Chang, Brian D. Tait, Rhonda Holdsworth, Andrew G. Brooks, Stephen P. Bottomley, Travis Beddoe, Chen Au Peh, Jamie Rossjohn, James McCluskey
Journal: Journal of Experimental Medicine
J Exp Med (2004) 200 (1): 13–24.
https://doi.org/10.1084/jem.20031680
Published: 28 June 2004
View article titled, Natural HLA Class I Polymorphism Controls the Pathway of Antigen Presentation and Susceptibility to Viral Evasion
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Includes: Supplementary data
Journal Articles

A Naturally Selected Dimorphism within the HLA-B44 Supertype Alters Class I Structure, Peptide Repertoire, and T Cell Recognition

Whitney A. Macdonald, Anthony W. Purcell, Nicole A. Mifsud, Lauren K. Ely, David S. Williams, Linus Chang, Jeffrey J. Gorman, Craig S. Clements, Lars Kjer-Nielsen, David M. Koelle, Scott R. Burrows, Brian D. Tait, Rhonda Holdsworth, Andrew G. Brooks, George O. Lovrecz, Louis Lu, Jamie Rossjohn, James McCluskey
Journal: Journal of Experimental Medicine
J Exp Med (2003) 198 (5): 679–691.
https://doi.org/10.1084/jem.20030066
Published: 25 August 2003
View article titled, A Naturally Selected Dimorphism within the HLA-B44 Supertype Alters Class I Structure, Peptide Repertoire, and T Cell Recognition
Open the PDF for A Naturally Selected Dimorphism within the HLA-B44 Supertype Alters Class I Structure, Peptide Repertoire, and T Cell Recognition in another window
Includes: Supplementary data