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Journal Articles

Native stem cell transcriptional circuits define cardinal features of high-risk leukemia

Qing Wang, Francesco Boccalatte, Jason Xu, Giovanni Gambi, Bettina Nadorp, Fatema Akter, Carea Mullin, Ashley F. Melnick, Elizabeth Choe, Anna C. McCarter, Nicole A. Jerome, Siyi Chen, Karena Lin, Sarah Khan, Rohan Kodgule, Jonathan H. Sussman, Petri Pölönen, Javier Rodriguez-Hernaez, Sonali Narang, Kleopatra Avrampou, Bryan King, Aristotelis Tsirigos, Russell J.H. Ryan, Charles G. Mullighan, David T. Teachey, Kai Tan, Iannis Aifantis, Mark Y. Chiang
Journal: Journal of Experimental Medicine
J Exp Med (2025) 222 (4): e20231349.
https://doi.org/10.1084/jem.20231349
Published: 19 February 2025
View article titled, Native stem cell transcriptional circuits define cardinal features of high-risk leukemia
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Includes: Supplementary data
Journal Articles

An iron-rich subset of macrophages promotes tumor growth through a Bach1-Ednrb axis

In Special Collection:
JEM Cancer Collection 2025 , Immunometabolism 2025 , Tissue Microenvironment and Immune Memory , Tumor Metabolism 2025 , 2024: The Year in Experimental Medicine
Ian W. Folkert, William A. Molina Arocho, Tsun Ki Jerrick To, Samir Devalaraja, Irene S. Molina, Jason Shoush, Hesham Mohei, Li Zhai, Md Naushad Akhtar, Veena Kochat, Emre Arslan, Alexander J. Lazar, Khalida Wani, William P. Israel, Zhan Zhang, Venkata S. Chaluvadi, Robert J. Norgard, Ying Liu, Ashley M. Fuller, Mai T. Dang, Robert E. Roses, Giorgos C. Karakousis, John T. Miura, Douglas L. Fraker, T.S. Karin Eisinger-Mathason, M. Celeste Simon, Kristy Weber, Kai Tan, Yi Fan, Kunal Rai, Malay Haldar
Journal: Journal of Experimental Medicine
J Exp Med (2024) 221 (10): e20230420.
https://doi.org/10.1084/jem.20230420
Published: 30 September 2024
View article titled, An iron-rich subset of macrophages promotes tumor growth through a Bach1-Ednrb axis
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Includes: Supplementary data
Journal Articles

Maturation of hematopoietic stem cells from prehematopoietic stem cells is accompanied by up-regulation of PD-L1

Joanna Tober, Marijke M.W. Maijenburg, Yan Li, Long Gao, Brandon K. Hadland, Peng Gao, Kodai Minoura, Irwin D. Bernstein, Kai Tan, Nancy A. Speck
Journal: Journal of Experimental Medicine
J Exp Med (2017) 215 (2): 645–659.
https://doi.org/10.1084/jem.20161594
Published: 27 December 2017
View article titled, Maturation of hematopoietic stem cells from prehematopoietic stem cells is accompanied by up-regulation of PD-L1
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Includes: Supplementary data
Journal Articles

Correction: Functional screen identifies regulators of murine hematopoietic stem cell repopulation

Per Holmfeldt, Miguel Ganuza, Himangi Marathe, Bing He, Trent Hall, Guolian Kang, Joseph Moen, Jennifer Pardieck, Angelica C. Saulsberry, Alba Cico, Ludovic Gaut, Daniel McGoldrick, David Finkelstein, Kai Tan, Shannon McKinney-Freeman
Journal: Journal of Experimental Medicine
J Exp Med (2016) 213 (11): 2525.
https://doi.org/10.1084/jem.2015080609232016c
Published: 27 September 2016
View article titled, Correction: Functional screen identifies regulators of murine hematopoietic stem cell repopulation
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Journal Articles

Functional screen identifies regulators of murine hematopoietic stem cell repopulation

Per Holmfeldt, Miguel Ganuza, Himangi Marathe, Bing He, Trent Hall, Guolian Kang, Joseph Moen, Jennifer Pardieck, Angelica C. Saulsberry, Alba Cico, Ludovic Gaut, Daniel McGoldrick, David Finkelstein, Kai Tan, Shannon McKinney-Freeman
Journal: Journal of Experimental Medicine
J Exp Med (2016) 213 (3): 433–449.
https://doi.org/10.1084/jem.20150806
Published: 15 February 2016
View article titled, Functional screen identifies regulators of murine hematopoietic stem cell repopulation
Open the PDF for Functional screen identifies regulators of murine hematopoietic stem cell repopulation in another window
Includes: Supplementary data