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Jason Pyrdol
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Journal Articles

Rapid CLIP dissociation from MHC II promotes an unusual antigen presentation pathway in autoimmunity

In Special Collection:
Autoimmunity: Mechanisms and Novel Treatments , Cancer and Autoimmunity
Yoshinaga Ito, Orr Ashenberg, Jason Pyrdol, Adrienne M. Luoma, Orit Rozenblatt-Rosen, Matan Hofree, Elena Christian, Lucas Ferrari de Andrade, Rong En Tay, Luc Teyton, Aviv Regev, Stephanie K. Dougan, Kai W. Wucherpfennig
Journal: Journal of Experimental Medicine
J Exp Med (2018) 215 (10): 2617–2635.
https://doi.org/10.1084/jem.20180300
Published: 05 September 2018
View articletitled, Rapid CLIP dissociation from MHC II promotes an unusual antigen presentation pathway in autoimmunity
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Includes: Supplementary data
Journal Articles

A highly tilted binding mode by a self-reactive T cell receptor results in altered engagement of peptide and MHC

Dhruv K. Sethi, David A. Schubert, Anne-Kathrin Anders, Annie Heroux, Daniel A. Bonsor, Chantz P. Thomas, Eric J. Sundberg, Jason Pyrdol, Kai W. Wucherpfennig
Journal: Journal of Experimental Medicine
J Exp Med (2011) 208 (1): 91–102.
https://doi.org/10.1084/jem.20100725
Published: 03 January 2011
View articletitled, A highly tilted binding mode by a self-reactive T cell receptor results in altered engagement of peptide and MHC
Open the PDF for A highly tilted binding mode by a self-reactive T cell receptor results in altered engagement of peptide and MHC in another window
Includes: Supplementary data
Journal Articles

Visualization of Myelin Basic Protein (Mbp) T Cell Epitopes in Multiple Sclerosis Lesions Using a Monoclonal Antibody Specific for the Human Histocompatibility Leukocyte Antigen (Hla)-Dr2–Mbp 85–99 Complex

Michelle Krogsgaard, Kai W. Wucherpfennig, Barbara Canella, Bjarke E. Hansen, Arne Svejgaard, Jason Pyrdol, Henrik Ditzel, Cedric Raine, Jan Engberg, Lars Fugger
Journal: Journal of Experimental Medicine
J Exp Med (2000) 191 (8): 1395–1412.
https://doi.org/10.1084/jem.191.8.1395
Published: 18 April 2000
View articletitled, Visualization of Myelin Basic Protein (Mbp) T Cell Epitopes in Multiple Sclerosis Lesions Using a Monoclonal Antibody Specific for the Human Histocompatibility Leukocyte Antigen (Hla)-Dr2–Mbp 85–99 Complex
Open the PDF for Visualization of Myelin Basic Protein (Mbp) T Cell Epitopes in Multiple Sclerosis Lesions Using a Monoclonal Antibody Specific for the Human Histocompatibility Leukocyte Antigen (Hla)-Dr2–Mbp 85–99 Complex in another window
Journal Articles

Crystal Structure of HLA-DR2 (DRA*0101, DRB1*1501) Complexed with a Peptide from Human Myelin Basic Protein

Kathrine J. Smith, Jason Pyrdol, Laurent Gauthier, Don C. Wiley, Kai W. Wucherpfennig
Journal: Journal of Experimental Medicine
J Exp Med (1998) 188 (8): 1511–1520.
https://doi.org/10.1084/jem.188.8.1511
Published: 19 October 1998
View articletitled, Crystal Structure of HLA-DR2 (DRA*0101, DRB1*1501) Complexed with a Peptide from Human Myelin Basic Protein
Open the PDF for Crystal Structure of HLA-DR2 (DRA*0101, DRB1*1501) Complexed with a Peptide from Human Myelin Basic Protein in another window