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LIME : A New Membrane Raft-associated Adaptor Protein Involved in CD4 and CD8 Coreceptor Signaling Preliminary reports (abstracts, poster, and oral communications) on some aspects of this work were presented at the ELSO2002 Meeting, Nice, June 29–July 3, 2002, 5th EFIS Tatra Immunology Conference, Tatranske Zruby, September 7–11, 2002, and 15th EFIS Meeting, Rhodes, June 2003. Abbreviations used in this paper: Cbp, Csk-binding protein; LAT, linker for activation of T cells; LAB, linker for activation of B cells; LIME, Lck-interacting molecule; NTAL, non–T cell activation linker; PAG, phosphoprotein associated with glycosphingolipid-enriched microdomains; PBL, peripheral blood leukocytes; PHA, phytohemagglutinin; PLCγ, phospholipase Cγ; PTK, protein tyrosine kinase; P-Tyr, phosphotyrosine; SH Src homology; TRAP, transmembrane adaptor protein; TRIM, TCR-interacting molecule.
Naděžda Brdičková, Tomáš Brdička, Pavla Angelisová, Ondrej Horváth, Jiří Špička, Ivan Hilgert, Jan Pačes, Luca Simeoni, Stefanie Kliche, Camilla Merten, Burkhart Schraven, Václav Hořejší
Journal: Journal of Experimental Medicine
J Exp Med (2003) 198 (10): 1453–1462.
Published: 10 November 2003