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James P. Di Santo
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Journal Articles

Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller

In Special Collection:
JEM Clinical Immunology Collection 2022 , Journal-Based CME Activities with Journal of Experimental Medicine (JEM) , HIV Latency and Beyond
Valérie Lorin, Ignacio Fernández, Guillemette Masse-Ranson, Mélanie Bouvin-Pley, Luis M. Molinos-Albert, Cyril Planchais, Thierry Hieu, Gérard Péhau-Arnaudet, Dominik Hrebík, Giulia Girelli-Zubani, Oriane Fiquet, Florence Guivel-Benhassine, Rogier W. Sanders, Bruce D. Walker, Olivier Schwartz, Johannes F. Scheid, Jordan D. Dimitrov, Pavel Plevka, Martine Braibant, Michael S. Seaman, François Bontems, James P. Di Santo, Félix A. Rey, Hugo Mouquet
Journal: Journal of Experimental Medicine
J Exp Med (2022) 219 (3): e20212045.
https://doi.org/10.1084/jem.20212045
Published: 01 March 2022
View articletitled, Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller
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Includes: Supplementary data
Journal Articles

CD116+ fetal precursors migrate to the perinatal lung and give rise to human alveolar macrophages

In Special Collection:
Stem Cell Collection 2022
Elza Evren, Emma Ringqvist, Jean-Marc Doisne, Anna Thaller, Natalie Sleiers, Richard A. Flavell, James P. Di Santo, Tim Willinger
Journal: Journal of Experimental Medicine
J Exp Med (2022) 219 (2): e20210987.
https://doi.org/10.1084/jem.20210987
Published: 12 January 2022
View articletitled, CD116+ fetal precursors migrate to the perinatal lung and give rise to human alveolar macrophages
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Includes: Supplementary data
Journal Articles

High Th2 cytokine levels and upper airway inflammation in human inherited T-bet deficiency

In Special Collection:
Cytokines Collection 2021 , Innate Immunity: From Basic Biology to Human Disease
Rui Yang, Marc Weisshaar, Federico Mele, Ibtihal Benhsaien, Karim Dorgham, Jing Han, Carys A. Croft, Samuele Notarbartolo, Jérémie Rosain, Paul Bastard, Anne Puel, Bernhard Fleckenstein, Laurie H. Glimcher, James P. Di Santo, Cindy S. Ma, Guy Gorochov, Aziz Bousfiha, Laurent Abel, Stuart G. Tangye, Jean-Laurent Casanova, Jacinta Bustamante, Federica Sallusto
Journal: Journal of Experimental Medicine
J Exp Med (2021) 218 (8): e20202726.
https://doi.org/10.1084/jem.20202726
Published: 23 June 2021
View articletitled, High Th2 cytokine levels and upper airway inflammation in human inherited T-bet deficiency
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Journal Articles

ILC3s control splenic cDC homeostasis via lymphotoxin signaling

Matthias Vanderkerken, Antonio P. Baptista, Marco De Giovanni, Satoshi Fukuyama, Robin Browaeys, Charlotte L. Scott, Paula S. Norris, Gerard Eberl, James P. Di Santo, Eric Vivier, Yvan Saeys, Hamida Hammad, Jason G. Cyster, Carl F. Ware, Alexei V. Tumanov, Carl De Trez, Bart N. Lambrecht
Journal: Journal of Experimental Medicine
J Exp Med (2021) 218 (5): e20190835.
https://doi.org/10.1084/jem.20190835
Published: 16 March 2021
View articletitled, ILC3s control splenic cDC homeostasis via lymphotoxin signaling
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Includes: Supplementary data
Journal Articles

Potent human broadly neutralizing antibodies to hepatitis B virus from natural controllers

In Special Collection:
Antibodies at the Forefront of Disease Treatment
Verena Hehle, Maxime Beretta, Maryline Bourgine, Malika Ait-Goughoulte, Cyril Planchais, Solen Morisse, Benjamin Vesin, Valérie Lorin, Thierry Hieu, Andrea Stauffer, Oriane Fiquet, Jordan D. Dimitrov, Marie-Louise Michel, Marie-Noëlle Ungeheuer, Camille Sureau, Stanislas Pol, James P. Di Santo, Hélène Strick-Marchand, Nadège Pelletier, Hugo Mouquet
Journal: Journal of Experimental Medicine
J Exp Med (2020) 217 (10): e20200840.
https://doi.org/10.1084/jem.20200840
Published: 24 June 2020
View articletitled, Potent human broadly neutralizing antibodies to hepatitis B virus from natural controllers
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Includes: Supplementary data
Journal Articles

Peyer’s patch myeloid cells infection by Listeria signals through gp38+ stromal cells and locks intestinal villus invasion

Olivier Disson, Camille Blériot, Jean-Marie Jacob, Nicolas Serafini, Sophie Dulauroy, Grégory Jouvion, Cindy Fevre, Grégoire Gessain, Pierre Thouvenot, Gérard Eberl, James P. Di Santo, Lucie Peduto, Marc Lecuit
Journal: Journal of Experimental Medicine
J Exp Med (2018) 215 (11): 2936–2954.
https://doi.org/10.1084/jem.20181210
Published: 24 October 2018
View articletitled, Peyer’s patch myeloid cells infection by Listeria signals through gp38+ stromal cells and locks intestinal villus invasion
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Includes: Supplementary data
Journal Articles

IL-12 drives functional plasticity of human group 2 innate lymphoid cells

Ai Ing Lim, Silvia Menegatti, Jacinta Bustamante, Lionel Le Bourhis, Matthieu Allez, Lars Rogge, Jean-Laurent Casanova, Hans Yssel, James P. Di Santo
Journal: Journal of Experimental Medicine
J Exp Med (2016) 213 (4): 569–583.
https://doi.org/10.1084/jem.20151750
Published: 14 March 2016
View articletitled, IL-12 drives functional plasticity of human group 2 innate lymphoid cells
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Includes: Supplementary data
Journal Articles

Gata3 drives development of RORγt+ group 3 innate lymphoid cells

Nicolas Serafini, Roel G.J. Klein Wolterink, Naoko Satoh-Takayama, Wei Xu, Christian A.J. Vosshenrich, Rudi W. Hendriks, James P. Di Santo
Journal: Journal of Experimental Medicine
J Exp Med (2014) 211 (2): 199–208.
https://doi.org/10.1084/jem.20131038
Published: 13 January 2014
View articletitled, Gata3 drives development of RORγt+ group 3 innate lymphoid cells
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Includes: Supplementary data
Journal Articles

Origin, trafficking, and intraepithelial fate of gut-tropic T cells

Delphine Guy-Grand, Pierre Vassalli, Gerard Eberl, Pablo Pereira, Odile Burlen-Defranoux, Fabrice Lemaitre, James P. Di Santo, Antonio A. Freitas, Ana Cumano, Antonio Bandeira
Journal: Journal of Experimental Medicine
J Exp Med (2013) 210 (11): 2493.
https://doi.org/10.1084/jem.20122588104c
Published: 14 October 2013
View articletitled, Origin, trafficking, and intraepithelial fate of gut-tropic T cells
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Journal Articles

Origin, trafficking, and intraepithelial fate of gut-tropic T cells

Delphine Guy-Grand, Pierre Vassalli, Gerard Eberl, Pablo Pereira, Odile Burlen-Defranoux, Fabrice Lemaitre, James P. Di Santo, Antonio A. Freitas, Ana Cumano, Antonio Bandeira
Journal: Journal of Experimental Medicine
J Exp Med (2013) 210 (9): 1839–1854.
https://doi.org/10.1084/jem.20122588
Published: 05 August 2013
View articletitled, Origin, trafficking, and intraepithelial fate of gut-tropic T cells
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Includes: Supplementary data
Journal Articles

Thymocytes may persist and differentiate without any input from bone marrow progenitors

Laetitia Peaudecerf, Sara Lemos, Alessia Galgano, Gerald Krenn, Florence Vasseur, James P. Di Santo, Sophie Ezine, Benedita Rocha
Journal: Journal of Experimental Medicine
J Exp Med (2012) 209 (8): 1401–1408.
https://doi.org/10.1084/jem.20120845
Published: 09 July 2012
View articletitled, Thymocytes may persist and differentiate without any input from bone marrow progenitors
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Includes: Supplementary data
Journal Articles

IL-7 and IL-15 independently program the differentiation of intestinal CD3−NKp46+ cell subsets from Id2-dependent precursors

Naoko Satoh-Takayama, Sarah Lesjean-Pottier, Paulo Vieira, Shinichiro Sawa, Gerard Eberl, Christian A.J. Vosshenrich, James P. Di Santo
Journal: Journal of Experimental Medicine
J Exp Med (2010) 207 (2): 273–280.
https://doi.org/10.1084/jem.20092029
Published: 08 February 2010
View articletitled, IL-7 and IL-15 independently program the differentiation of intestinal CD3−NKp46+ cell subsets from Id2-dependent precursors
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Includes: Supplementary data
Journal Articles

IL-15 trans-presentation promotes human NK cell development and differentiation in vivo

Nicholas D. Huntington, Nicolas Legrand, Nuno L. Alves, Barbara Jaron, Kees Weijer, Ariane Plet, Erwan Corcuff, Erwan Mortier, Yannick Jacques, Hergen Spits, James P. Di Santo
Journal: Journal of Experimental Medicine
J Exp Med (2008) 206 (1): 25–34.
https://doi.org/10.1084/jem.20082013
Published: 22 December 2008
View articletitled, IL-15 trans-presentation promotes human NK cell development and differentiation in vivo
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Includes: Supplementary data
Journal Articles

In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORγt+ T cells

Matthias Lochner, Lucie Peduto, Marie Cherrier, Shinichiro Sawa, Francina Langa, Rosa Varona, Dieter Riethmacher, Mustapha Si-Tahar, James P. Di Santo, Gérard Eberl
Journal: Journal of Experimental Medicine
J Exp Med (2008) 205 (6): 1381–1393.
https://doi.org/10.1084/jem.20080034
Published: 26 May 2008
View articletitled, In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORγt+ T cells
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Includes: Supplementary data
Journal Articles

CD11cloB220+ interferon-producing killer dendritic cells are activated natural killer cells

Christian A.J. Vosshenrich, Sarah Lesjean-Pottier, Milena Hasan, Odile Richard-Le Goff, Erwan Corcuff, Ofer Mandelboim, James P. Di Santo
Journal: Journal of Experimental Medicine
J Exp Med (2007) 204 (11): 2569–2578.
https://doi.org/10.1084/jem.20071451
Published: 08 October 2007
View articletitled, CD11cloB220+ interferon-producing killer dendritic cells are activated natural killer cells
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Includes: Supplementary data
Journal Articles

Are Major Histocompatibility Complex Molecules Involved in the Survival of Naive CD4+ T Cells?

Isabelle Grandjean, Livine Duban, Elizabeth A. Bonney, Erwan Corcuff, James P. Di Santo, Polly Matzinger, Olivier Lantz
Journal: Journal of Experimental Medicine
J Exp Med (2003) 198 (7): 1089–1102.
https://doi.org/10.1084/jem.20030963
Published: 29 September 2003
View articletitled, Are Major Histocompatibility Complex Molecules Involved in the Survival of Naive CD4+ T Cells?
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Includes: Supplementary data
Journal Articles

Functional Dichotomy in Natural Killer Cell Signaling: Vav1-Dependent and -Independent Mechanisms

Francesco Colucci, Eleftheria Rosmaraki, Søren Bregenholt, Sandrine I. Samson, Vincenzo Di Bartolo, Martin Turner, Lesley Vanes, Victor Tybulewicz, James P. Di Santo
Journal: Journal of Experimental Medicine
J Exp Med (2001) 193 (12): 1413–1424.
https://doi.org/10.1084/jem.193.12.1413
Published: 18 June 2001
View articletitled, Functional Dichotomy in Natural Killer Cell Signaling: Vav1-Dependent and -Independent Mechanisms
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Journal Articles

Cloning of the Murine Thymic Stromal Lymphopoietin (Tslp) Receptor: Formation of a Functional Heteromeric Complex Requires Interleukin 7 Receptor

Linda S. Park, Unja Martin, Kirsten Garka, Brian Gliniak, James P. Di Santo, Werner Muller, David A. Largaespada, Neal G. Copeland, Nancy A. Jenkins, Andrew G. Farr, Steven F. Ziegler, Philip J. Morrissey, Raymond Paxton, John E. Sims
Journal: Journal of Experimental Medicine
J Exp Med (2000) 192 (5): 659–670.
https://doi.org/10.1084/jem.192.5.659
Published: 28 August 2000
View articletitled, Cloning of the Murine Thymic Stromal Lymphopoietin (Tslp) Receptor: Formation of a Functional Heteromeric Complex Requires Interleukin 7 Receptor
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Journal Articles

Interferon γ Contributes to Initiation of Uterine Vascular Modification, Decidual Integrity, and Uterine Natural Killer Cell Maturation during Normal Murine Pregnancy

Ali A. Ashkar, James P. Di Santo, B. Anne Croy
Journal: Journal of Experimental Medicine
J Exp Med (2000) 192 (2): 259–270.
https://doi.org/10.1084/jem.192.2.259
Published: 17 July 2000
View articletitled, Interferon γ Contributes to Initiation of Uterine Vascular Modification, Decidual Integrity, and Uterine Natural Killer Cell Maturation during Normal Murine Pregnancy
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Journal Articles

Early T Cell Receptor β Gene Expression Is Regulated by the Pre-T Cell Receptor–CD3 Complex

Iannis Aifantis, Jacqueline Feinberg, Hans Jörg Fehling, James P. Di Santo, Harald von Boehmer
Journal: Journal of Experimental Medicine
J Exp Med (1999) 190 (1): 141–144.
https://doi.org/10.1084/jem.190.1.141
Published: 05 July 1999
View articletitled, Early T Cell Receptor β Gene Expression Is Regulated by the Pre-T Cell Receptor–CD3 Complex
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