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Isabella Rauch
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Journal Articles

Enteric tuft cell inflammasome activation drives NKp46+ILC3 IL22 via PGD2 and inhibits Salmonella

Madeline J. Churchill, Ankit Pandeya, Renate Bauer, Tighe Christopher, Stefanie Krug, Roslyn Honodel, Shuchi Smita, Lindsey Warner, Bridget M. Mooney, Alexis R. Gibson, Patrick S. Mitchell, Elia D. Tait Wojno, Isabella Rauch
Journal: Journal of Experimental Medicine
J Exp Med (2025) 222 (6): e20230803.
https://doi.org/10.1084/jem.20230803
Published: 13 March 2025
View articletitled, Enteric tuft cell inflammasome activation drives NKp46+ILC3 IL22 via PGD2 and inhibits Salmonella
Open the PDF for Enteric tuft cell inflammasome activation drives NKp46+ILC3 IL22 via PGD2 and inhibits Salmonella in another window
Includes: Supplementary data
Journal Articles

PGD2 and CRTH2 counteract Type 2 cytokine–elicited intestinal epithelial responses during helminth infection

In Special Collection:
Cytokines Collection 2021 , Immunology Update Winter 2022 , The Inflammasomes: From Mechanism to Therapeutics
Oyebola O. Oyesola, Michael T. Shanahan, Matt Kanke, Bridget M. Mooney, Lauren M. Webb, Shuchi Smita, Macy K. Matheson, Pamela Campioli, Duc Pham, Simon P. Früh, John W. McGinty, Madeline J. Churchill, Jordan L. Cahoon, Pavithra Sundaravaradan, Becca A. Flitter, Karthik Mouli, Marija S. Nadjsombati, Elena Kamynina, Seth A. Peng, Rebecca L. Cubitt, Karsten Gronert, James D. Lord, Isabella Rauch, Jakob von Moltke, Praveen Sethupathy, Elia D. Tait Wojno
Journal: Journal of Experimental Medicine
J Exp Med (2021) 218 (9): e20202178.
https://doi.org/10.1084/jem.20202178
Published: 20 July 2021
View articletitled, PGD2 and CRTH2 counteract Type 2 cytokine–elicited intestinal epithelial responses during helminth infection
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Journal Articles

NLRC4 inflammasome activation is NLRP3- and phosphorylation-independent during infection and does not protect from melanoma

In Special Collection:
Inflammasome Signaling , The Inflammasomes: From Mechanism to Therapeutics , Innate Immune Signaling in Disease and Homeostasis , JEM 2020 Update on Cancer Immunology and Immunotherapy
Jeannette L. Tenthorey, Roberto A. Chavez, Thornton W. Thompson, Katherine A. Deets, Russell E. Vance, Isabella Rauch
Journal: Journal of Experimental Medicine
J Exp Med (2020) 217 (7): e20191736.
https://doi.org/10.1084/jem.20191736
Published: 27 April 2020
View articletitled, NLRC4 inflammasome activation is NLRP3- and phosphorylation-independent during infection and does not protect from melanoma
Open the PDF for NLRC4 inflammasome activation is NLRP3- and phosphorylation-independent during infection and does not protect from melanoma in another window
Journal Articles

Transcriptional profiling identifies caspase-1 as a T cell–intrinsic regulator of Th17 differentiation

In Special Collection:
Immunology: New Insights and Resources , Cytokines Collection 2020
Yajing Gao, Krystin Deason, Aakanksha Jain, Ricardo A. Irizarry-Caro, Igor Dozmorov, Laura A. Coughlin, Isabella Rauch, Bret M. Evers, Andrew Y. Koh, Edward K. Wakeland, Chandrashekhar Pasare
Journal: Journal of Experimental Medicine
J Exp Med (2020) 217 (4): e20190476.
https://doi.org/10.1084/jem.20190476
Published: 22 January 2020
View articletitled, Transcriptional profiling identifies caspase-1 as a T cell–intrinsic regulator of Th17 differentiation
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Includes: Supplementary data
Journal Articles

NAIP proteins are required for cytosolic detection of specific bacterial ligands in vivo

Isabella Rauch, Jeannette L. Tenthorey, Randilea D. Nichols, Khatoun Al Moussawi, James J. Kang, Chulho Kang, Barbara I. Kazmierczak, Russell E. Vance
Journal: Journal of Experimental Medicine
J Exp Med (2016) 213 (5): 657–665.
https://doi.org/10.1084/jem.20151809
Published: 04 April 2016
View articletitled, NAIP proteins are required for cytosolic detection of specific bacterial ligands in vivo
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