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Human CD127 negative ILC2s show immunological memory

In Special Collection:

Innate Lymphoid Cells 2024

J Exp Med (2024) 221 (8): e20231827.

https://doi.org/10.1084/jem.20231827

Published: 18 June 2024

View article titled, Human CD127 negative ILC2s show immunological memory

Journal Articles

Characterization of human FDCs reveals regulation of T cells and antigen presentation to B cells

Balthasar A. Heesters, Kyah van Megesen, Ilhan Tomris, Robert P. de Vries, Giuliana Magri, Hergen Spits

J Exp Med (2021) 218 (10): e20210790.

https://doi.org/10.1084/jem.20210790

Published: 23 August 2021

View article titled, Characterization of human FDCs reveals regulation of T cells and antigen presentation to B cells

Journal Articles

Correction: KLRG1 and NKp46 discriminate subpopulations of human CD117⁺CRTH2⁻ ILCs biased toward ILC2 or ILC3

Maho Nagasawa, Balthasar A. Heesters, Chantal M.A. Kradolfer, Lisette Krabbendam, Itziar Martinez-Gonzalez, Marjolein J.W. de Bruijn, Korneliusz Golebski, Rudi W. Hendriks, Ralph Stadhouders, Hergen Spits, Suzanne M. Bal

J Exp Med (2019) 216 (9): 2221–2222.

https://doi.org/10.1084/jem.2019049007302019c

Published: 06 August 2019

View article titled, Correction: KLRG1 and NKp46 discriminate subpopulations of human CD117+CRTH2− ILCs biased toward ILC2 or ILC3

Journal Articles

KLRG1 and NKp46 discriminate subpopulations of human CD117⁺CRTH2⁻ ILCs biased toward ILC2 or ILC3

J Exp Med (2019) 216 (8): 1762–1776.

https://doi.org/10.1084/jem.20190490

Published: 14 June 2019

View article titled, KLRG1 and NKp46 discriminate subpopulations of human CD117+CRTH2− ILCs biased toward ILC2 or ILC3

Includes: Supplementary data

Journal Articles

Human NKp44⁺IL-22⁺ cells and LTi-like cells constitute a stable RORC⁺ lineage distinct from conventional natural killer cells

Natasha K. Crellin, Sara Trifari, Charles D. Kaplan, Tom Cupedo, Hergen Spits

J Exp Med (2010) 207 (2): 281–290.

https://doi.org/10.1084/jem.20091509

Published: 08 February 2010

View article titled, Human NKp44+IL-22+ cells and LTi-like cells constitute a stable RORC+ lineage distinct from conventional natural killer cells

Includes: Supplementary data

Journal Articles

Phosphoinositide-dependent kinase 1 controls migration and malignant transformation but not cell growth and proliferation in PTEN-null lymphocytes

David K. Finlay, Linda V. Sinclair, Carmen Feijoo, Caryll M. Waugh, Thijs J. Hagenbeek, Hergen Spits, Doreen A. Cantrell

J Exp Med (2009) 206 (11): 2441–2454.

https://doi.org/10.1084/jem.20090219

Published: 05 October 2009

View article titled, Phosphoinositide-dependent kinase 1 controls migration and malignant transformation but not cell growth and proliferation in PTEN-null lymphocytes

Journal Articles

IL-15 trans-presentation promotes human NK cell development and differentiation in vivo

Nicholas D. Huntington, Nicolas Legrand, Nuno L. Alves, Barbara Jaron, Kees Weijer, Ariane Plet, Erwan Corcuff, Erwan Mortier, Yannick Jacques, Hergen Spits, James P. Di Santo

J Exp Med (2008) 206 (1): 25–34.

https://doi.org/10.1084/jem.20082013

Published: 22 December 2008

View article titled, IL-15 trans-presentation promotes human NK cell development and differentiation in vivo

Includes: Supplementary data

Journal Articles

T cell–independent development and induction of somatic hypermutation in human IgM⁺IgD⁺CD27⁺ B cells

Ferenc A. Scheeren, Maho Nagasawa, Kees Weijer, Tom Cupedo, Jörg Kirberg, Nicolas Legrand, Hergen Spits

J Exp Med (2008) 205 (9): 2033–2042.

https://doi.org/10.1084/jem.20070447

Published: 11 August 2008

View article titled, T cell–independent development and induction of somatic hypermutation in human IgM+IgD+CD27+ B cells

Includes: Supplementary data

Journal Articles

Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy

Eric A. Reits, James W. Hodge, Carla A. Herberts, Tom A. Groothuis, Mala Chakraborty, Elizabeth K.Wansley, Kevin Camphausen, Rosalie M. Luiten, Arnold H. de Ru, Joost Neijssen, Alexander Griekspoor, Elly Mesman, Frank A. Verreck, Hergen Spits, Jeffrey Schlom, Peter van Veelen, Jacques J. Neefjes

J Exp Med (2006) 203 (5): 1259–1271.

https://doi.org/10.1084/jem.20052494

Published: 24 April 2006

View article titled, Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy

Journal Articles

The ETS Transcription Factor Spi-B Is Required for Human Plasmacytoid Dendritic Cell Development

Remko Schotte, Maho Nagasawa, Kees Weijer, Hergen Spits, Bianca Blom

J Exp Med (2004) 200 (11): 1503–1509.

https://doi.org/10.1084/jem.20041231

Published: 06 December 2004

View article titled, The ETS Transcription Factor Spi-B Is Required for Human Plasmacytoid Dendritic Cell Development

Journal Articles

The Loss of PTEN Allows TCR αβ Lineage Thymocytes to Bypass IL-7 and Pre-TCR–mediated Signaling

Thijs J. Hagenbeek, Marianne Naspetti, Fabrice Malergue, Fabien Garçon, Jacques A. Nunès, Kitty B.J.M. Cleutjens, Jan Trapman, Paul Krimpenfort, Hergen Spits

J Exp Med (2004) 200 (7): 883–894.

https://doi.org/10.1084/jem.20040495

Published: 27 September 2004

View article titled, The Loss of PTEN Allows TCR αβ Lineage Thymocytes to Bypass IL-7 and Pre-TCR–mediated Signaling

Journal Articles

Id2 and Id3 Inhibit Development of Cd34⁺ Stem Cells into Predendritic Cell (Pre-Dc)2 but Not into Pre-Dc1: Evidence for a Lymphoid Origin of Pre-Dc2

Hergen Spits, Franka Couwenberg, Arjen Q. Bakker, Kees Weijer, Christel H. Uittenbogaart

J Exp Med (2000) 192 (12): 1775–1784.

https://doi.org/10.1084/jem.192.12.1775

Published: 18 December 2000

View article titled, Id2 and Id3 Inhibit Development of Cd34+ Stem Cells into Predendritic Cell (Pre-Dc)2 but Not into Pre-Dc1: <subtitle>Evidence for a Lymphoid Origin of Pre-Dc2</subtitle>

Journal Articles

Pim1 Reconstitutes Thymus Cellularity in Interleukin 7–And Common γ Chain–Mutant Mice and Permits Thymocyte Maturation in Rag- but Not Cd3γ-Deficient Mice

Heinz Jacobs, Paul Krimpenfort, Mariëlle Haks, John Allen, Bianca Blom, Corinne Démollière, Ada Kruisbeek, Hergen Spits, Anton Berns

J Exp Med (1999) 190 (8): 1059–1068.

https://doi.org/10.1084/jem.190.8.1059

Published: 18 October 1999

View article titled, Pim1 Reconstitutes Thymus Cellularity in Interleukin 7–And Common γ Chain–Mutant Mice and Permits Thymocyte Maturation in Rag- but Not Cd3γ-Deficient Mice

Journal Articles

Inhibition of T Cell and Promotion of Natural Killer Cell Development by the Dominant Negative Helix Loop Helix Factor Id3

Mirjam H.M. Heemskerk, Bianca Blom, Garry Nolan, Alexander P.A. Stegmann, Arjen Q. Bakker, Kees Weijer, Pieter C.M. Res, Hergen Spits

J Exp Med (1997) 186 (9): 1597–1602.

https://doi.org/10.1084/jem.186.9.1597

Published: 03 November 1997

View article titled, Inhibition of T Cell and Promotion of Natural Killer Cell Development by the Dominant Negative Helix Loop Helix Factor Id3

Journal Articles

A New Mechanism of NK Cell Cytotoxicity Activation: The CD40–CD40 Ligand Interaction

Ennio Carbone, Giuseppina Ruggiero, Giuseppe Terrazzano, Carmen Palomba, Ciro Manzo, Silvia Fontana, Hergen Spits, Klas Kärre, Serafino Zappacosta

J Exp Med (1997) 185 (12): 2053–2060.

https://doi.org/10.1084/jem.185.12.2053

Published: 16 June 1997

View article titled, A New Mechanism of NK Cell Cytotoxicity Activation: The CD40–CD40 Ligand Interaction

Journal Articles

Identification of a Committed T Cell Precursor Population in Adult Human Peripheral Blood

Ludovica Bruno, Pieter Res, Mark Dessing, Marina Cella, Hergen Spits

J Exp Med (1997) 185 (5): 875–884.

https://doi.org/10.1084/jem.185.5.875

Published: 03 March 1997

View article titled, Identification of a Committed T Cell Precursor Population in Adult Human Peripheral Blood

Journal Articles

Downregulation of CD1 Marks Acquisition of Functional Maturation of Human Thymocytes and Defines a Control Point in Late Stages of Human T Cell Development

Pieter Res, Bianca Blom, Toshiyuki Hori, Kees Weijer, Hergen Spits

J Exp Med (1997) 185 (1): 141–152.

https://doi.org/10.1084/jem.185.1.141

Published: 01 January 1997

View article titled, Downregulation of CD1 Marks Acquisition of Functional Maturation of Human Thymocytes and Defines a Control Point in Late Stages of Human T Cell Development

NARROW

Human CD127 negative ILC2s show immunological memory

Characterization of human FDCs reveals regulation of T cells and antigen presentation to B cells

Correction: KLRG1 and NKp46 discriminate subpopulations of human CD117⁺CRTH2⁻ ILCs biased toward ILC2 or ILC3

KLRG1 and NKp46 discriminate subpopulations of human CD117⁺CRTH2⁻ ILCs biased toward ILC2 or ILC3

Human NKp44⁺IL-22⁺ cells and LTi-like cells constitute a stable RORC⁺ lineage distinct from conventional natural killer cells

Phosphoinositide-dependent kinase 1 controls migration and malignant transformation but not cell growth and proliferation in PTEN-null lymphocytes

IL-15 trans-presentation promotes human NK cell development and differentiation in vivo

T cell–independent development and induction of somatic hypermutation in human IgM⁺IgD⁺CD27⁺ B cells

Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy

The ETS Transcription Factor Spi-B Is Required for Human Plasmacytoid Dendritic Cell Development

The Loss of PTEN Allows TCR αβ Lineage Thymocytes to Bypass IL-7 and Pre-TCR–mediated Signaling

Id2 and Id3 Inhibit Development of Cd34⁺ Stem Cells into Predendritic Cell (Pre-Dc)2 but Not into Pre-Dc1: Evidence for a Lymphoid Origin of Pre-Dc2

Pim1 Reconstitutes Thymus Cellularity in Interleukin 7–And Common γ Chain–Mutant Mice and Permits Thymocyte Maturation in Rag- but Not Cd3γ-Deficient Mice

Inhibition of T Cell and Promotion of Natural Killer Cell Development by the Dominant Negative Helix Loop Helix Factor Id3

A New Mechanism of NK Cell Cytotoxicity Activation: The CD40–CD40 Ligand Interaction

Identification of a Committed T Cell Precursor Population in Adult Human Peripheral Blood

Downregulation of CD1 Marks Acquisition of Functional Maturation of Human Thymocytes and Defines a Control Point in Late Stages of Human T Cell Development

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