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How to induce protective humoral immunity against Plasmodium falciparum circumsporozoite protein

Ilka Wahl, Hedda Wardemann

J Exp Med (2022) 219 (2): e20201313.

DOI: https://doi.org/10.1084/jem.20201313

Published: 10 January 2022

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Journal Articles

A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity

In Special Collection:

Antibodies at the Forefront of Disease Treatment

Elaine Thai, Giulia Costa, Anna Weyrich, Rajagopal Murugan, David Oyen, Yevel Flores-Garcia, Katherine Prieto, Alexandre Bosch, Angelo Valleriani, Nicholas C. Wu, Tossapol Pholcharee, Stephen W. Scally, Ian A. Wilson, Hedda Wardemann, Jean-Philippe Julien, Elena A. Levashina

J Exp Med (2020) 217 (11): e20200061.

DOI: https://doi.org/10.1084/jem.20200061

Published: 13 August 2020

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Includes: Supplementary data

Journal Articles

High microbiota reactivity of adult human intestinal IgA requires somatic mutations

Johanna Kabbert, Julia Benckert, Tim Rollenske, Thomas C.A. Hitch, Thomas Clavel, Vuk Cerovic, Hedda Wardemann, Oliver Pabst

J Exp Med (2020) 217 (11): e20200275.

DOI: https://doi.org/10.1084/jem.20200275

Published: 08 July 2020

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Includes: Supplementary data

Journal Articles

Correction: Human IgA bind a diverse array of commensal bacteria

J Exp Med (2020) 217 (3): e2018163501152020c.

DOI: https://doi.org/10.1084/jem.2018163501152020c

Published: 28 January 2020

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Journal Articles

Human IgA binds a diverse array of commensal bacteria

In Special Collection:

Immunology: New Insights and Resources , Tissue immune responses: immune cells and mechanisms

J Exp Med (2019) 217 (3): e20181635.

DOI: https://doi.org/10.1084/jem.20181635

Published: 31 December 2019

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Includes: Supplementary data

Journal Articles

Retraction: Monoclonal IgG antibodies generated from joint-derived B cells of RA patients have a strong bias toward citrullinated autoantigen recognition

Khaled Amara, Johanna Steen, Fiona Murray, Henner Morbach, Blanca M. Fernandez-Rodriguez, Vijay Joshua, Marianne Engström, Omri Snir, Lena Israelsson, Anca I. Catrina, Hedda Wardemann, Davide Corti, Eric Meffre, Lars Klareskog, Vivianne Malmström

J Exp Med (2018) 216 (1): 245.

DOI: https://doi.org/10.1084/jem.2012148612112018r

Published: 19 December 2018

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Journal Articles

Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection

Stephen W. Scally, Rajagopal Murugan, Alexandre Bosch, Gianna Triller, Giulia Costa, Benjamin Mordmüller, Peter G. Kremsner, B. Kim Lee Sim, Stephen L. Hoffman, Elena A. Levashina, Hedda Wardemann, Jean-Philippe Julien

J Exp Med (2017) 215 (1): 63–75.

DOI: https://doi.org/10.1084/jem.20170869

Published: 22 November 2017

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Includes: Supplementary data

Journal Articles

Monoclonal IgG antibodies generated from joint-derived B cells of RA patients have a strong bias toward citrullinated autoantigen recognition

J Exp Med (2013) 210 (3): 445–455.

DOI: https://doi.org/10.1084/jem.20121486

Published: 25 February 2013

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Includes: Supplementary data

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Atypical and classical memory B cells produce Plasmodium falciparum neutralizing antibodies

Matthias F. Muellenbeck, Beatrix Ueberheide, Borko Amulic, Alexandra Epp, David Fenyo, Christian E. Busse, Meral Esen, Michael Theisen, Benjamin Mordmüller, Hedda Wardemann

J Exp Med (2013) 210 (2): 389–399.

DOI: https://doi.org/10.1084/jem.20121970

Published: 14 January 2013

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Includes: Supplementary data

Journal Articles

Development of self-reactive germinal center B cells and plasma cells in autoimmune FcγRIIB-deficient mice

Thomas Tiller, Juliane Kofer, Cornelia Kreschel, Christian E. Busse, Stefan Riebel, Susanne Wickert, Felix Oden, Maria M.M. Mertes, Marc Ehlers, Hedda Wardemann

J Exp Med (2010) 207 (12): 2767–2778.

DOI: https://doi.org/10.1084/jem.20100171

Published: 15 November 2010

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Includes: Supplementary data

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Homeostatic expansion of autoreactive immunoglobulin-secreting cells in the Rag2 mouse model of Omenn syndrome

Barbara Cassani, Pietro Luigi Poliani, Veronica Marrella, Francesca Schena, Aisha V. Sauer, Maria Ravanini, Dario Strina, Christian E. Busse, Stephan Regenass, Hedda Wardemann, Alberto Martini, Fabio Facchetti, Mirjam van der Burg, Antonius G. Rolink, Paolo Vezzoni, Fabio Grassi, Elisabetta Traggiai, Anna Villa

J Exp Med (2010) 207 (7): 1525–1540.

DOI: https://doi.org/10.1084/jem.20091928

Published: 14 June 2010

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Includes: Supplementary data

Journal Articles

Persistent expression of autoantibodies in SLE patients in remission

Sergey Yurasov, Thomas Tiller, Makoto Tsuiji, Klara Velinzon, Virginia Pascual, Hedda Wardemann, Michel C. Nussenzweig

J Exp Med (2006) 203 (10): 2255–2261.

DOI: https://doi.org/10.1084/jem.20061446

Published: 11 September 2006

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Includes: Supplementary data

Journal Articles

A checkpoint for autoreactivity in human IgM⁺ memory B cell development

Makoto Tsuiji, Sergey Yurasov, Klara Velinzon, Saskia Thomas, Michel C. Nussenzweig, Hedda Wardemann

J Exp Med (2006) 203 (2): 393–400.

DOI: https://doi.org/10.1084/jem.20052033

Published: 30 January 2006

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Includes: Supplementary data

Journal Articles

Defective B cell tolerance checkpoints in systemic lupus erythematosus

Sergey Yurasov, Hedda Wardemann, Johanna Hammersen, Makoto Tsuiji, Eric Meffre, Virginia Pascual, Michel C. Nussenzweig

J Exp Med (2005) 201 (5): 703–711.

DOI: https://doi.org/10.1084/jem.20042251

Published: 28 February 2005

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Includes: Supplementary data

Journal Articles

Bruton's Tyrosine Kinase Is Essential for Human B Cell Tolerance

Yen-Shing Ng, Hedda Wardemann, James Chelnis, Charlotte Cunningham-Rundles, Eric Meffre

J Exp Med (2004) 200 (7): 927–934.

DOI: https://doi.org/10.1084/jem.20040920

Published: 04 October 2004

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Includes: Supplementary data

Journal Articles

Human Autoantibody Silencing by Immunoglobulin Light Chains

Hedda Wardemann, Johanna Hammersen, Michel C. Nussenzweig

J Exp Med (2004) 200 (2): 191–199.

DOI: https://doi.org/10.1084/jem.20040818

Published: 19 July 2004

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Includes: Supplementary data

Journal Articles

Surrogate Light Chain Expressing Human Peripheral B Cells Produce Self-reactive Antibodies

Eric Meffre, Anne Schaefer, Hedda Wardemann, Patrick Wilson, Eric Davis, Michel C. Nussenzweig

J Exp Med (2003) 199 (1): 145–150.

DOI: https://doi.org/10.1084/jem.20031550

Published: 29 December 2003

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Includes: Supplementary data

Journal Articles

B-1a B Cells that Link the Innate and Adaptive Immune Responses Are Lacking in the Absence of the Spleen

Hedda Wardemann, Thomas Boehm, Neil Dear, Rita Carsetti

J Exp Med (2002) 195 (6): 771–780.

DOI: https://doi.org/10.1084/jem.20011140

Published: 18 March 2002

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NARROW

How to induce protective humoral immunity against Plasmodium falciparum circumsporozoite protein

A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity

High microbiota reactivity of adult human intestinal IgA requires somatic mutations

Correction: Human IgA bind a diverse array of commensal bacteria

Human IgA binds a diverse array of commensal bacteria

Retraction: Monoclonal IgG antibodies generated from joint-derived B cells of RA patients have a strong bias toward citrullinated autoantigen recognition

Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection

Monoclonal IgG antibodies generated from joint-derived B cells of RA patients have a strong bias toward citrullinated autoantigen recognition

Atypical and classical memory B cells produce Plasmodium falciparum neutralizing antibodies

Development of self-reactive germinal center B cells and plasma cells in autoimmune FcγRIIB-deficient mice

Homeostatic expansion of autoreactive immunoglobulin-secreting cells in the Rag2 mouse model of Omenn syndrome

Persistent expression of autoantibodies in SLE patients in remission

A checkpoint for autoreactivity in human IgM⁺ memory B cell development

Defective B cell tolerance checkpoints in systemic lupus erythematosus

Bruton's Tyrosine Kinase Is Essential for Human B Cell Tolerance

Human Autoantibody Silencing by Immunoglobulin Light Chains

Surrogate Light Chain Expressing Human Peripheral B Cells Produce Self-reactive Antibodies

B-1a B Cells that Link the Innate and Adaptive Immune Responses Are Lacking in the Absence of the Spleen

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