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Doron Merkler
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Journal Articles

Persistent RNA virus infection is short-lived at the single-cell level but leaves transcriptomic footprints

Peter Reuther, Katrin Martin, Mario Kreutzfeldt, Matias Ciancaglini, Florian Geier, Diego Calabrese, Doron Merkler, Daniel D. Pinschewer
Journal: Journal of Experimental Medicine
J Exp Med (2021) 218 (10): e20210408.
https://doi.org/10.1084/jem.20210408
Published: 16 August 2021
View article titled, Persistent RNA virus infection is short-lived at the single-cell level but leaves transcriptomic footprints
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Includes: Supplementary data
Journal Articles

Neuronal metabotropic glutamate receptor 8 protects against neurodegeneration in CNS inflammation

Marcel S. Woo, Friederike Ufer, Nicola Rothammer, Giovanni Di Liberto, Lars Binkle, Undine Haferkamp, Jana K. Sonner, Jan Broder Engler, Sönke Hornig, Simone Bauer, Ingrid Wagner, Kristof Egervari, Jacob Raber, Robert M. Duvoisin, Ole Pless, Doron Merkler, Manuel A. Friese
Journal: Journal of Experimental Medicine
J Exp Med (2021) 218 (5): e20201290.
https://doi.org/10.1084/jem.20201290
Published: 04 March 2021
View article titled, Neuronal metabotropic glutamate receptor 8 protects against neurodegeneration in CNS inflammation
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Includes: Supplementary data
Journal Articles

The Rho regulator Myosin IXb enables nonlymphoid tissue seeding of protective CD8+ T cells

Federica Moalli, Xenia Ficht, Philipp Germann, Mykhailo Vladymyrov, Bettina Stolp, Ingrid de Vries, Ruth Lyck, Jasmin Balmer, Amleto Fiocchi, Mario Kreutzfeldt, Doron Merkler, Matteo Iannacone, Akitaka Ariga, Michael H. Stoffel, James Sharpe, Martin Bähler, Michael Sixt, Alba Diz-Muñoz, Jens V. Stein
Journal: Journal of Experimental Medicine
J Exp Med (2018) 215 (7): 1869–1890.
https://doi.org/10.1084/jem.20170896
Published: 06 June 2018
View article titled, The Rho regulator Myosin IXb enables nonlymphoid tissue seeding of protective CD8<sup>+</sup> T cells
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Includes: Supplementary data
Journal Articles

pMHC affinity controls duration of CD8+ T cell–DC interactions and imprints timing of effector differentiation versus expansion

Aleksandra J. Ozga, Federica Moalli, Jun Abe, Jim Swoger, James Sharpe, Dietmar Zehn, Mario Kreutzfeldt, Doron Merkler, Jorge Ripoll, Jens V. Stein
Journal: Journal of Experimental Medicine
J Exp Med (2016) 213 (12): 2811–2829.
https://doi.org/10.1084/jem.20160206
Published: 31 October 2016
View article titled, pMHC affinity controls duration of CD8<sup>+</sup> T cell–DC interactions and imprints timing of effector differentiation versus expansion
Open the PDF for pMHC affinity controls duration of CD8<sup>+</sup> T cell–DC interactions and imprints timing of effector differentiation versus expansion in another window
Includes: Supplementary data
Journal Articles

Brain-resident memory T cells represent an autonomous cytotoxic barrier to viral infection

Karin Steinbach, Ilena Vincenti, Mario Kreutzfeldt, Nicolas Page, Andreas Muschaweckh, Ingrid Wagner, Ingo Drexler, Daniel Pinschewer, Thomas Korn, Doron Merkler
Journal: Journal of Experimental Medicine
J Exp Med (2016) 213 (8): 1571–1587.
https://doi.org/10.1084/jem.20151916
Published: 04 July 2016
View article titled, Brain-resident memory T cells represent an autonomous cytotoxic barrier to viral infection
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Includes: Supplementary data
Journal Articles

Neuroprotective intervention by interferon-γ blockade prevents CD8+ T cell–mediated dendrite and synapse loss

Mario Kreutzfeldt, Andreas Bergthaler, Marylise Fernandez, Wolfgang Brück, Karin Steinbach, Mariann Vorm, Roland Coras, Ingmar Blümcke, Weldy V. Bonilla, Anne Fleige, Ruth Forman, Werner Müller, Burkhard Becher, Thomas Misgeld, Martin Kerschensteiner, Daniel D. Pinschewer, Doron Merkler
Journal: Journal of Experimental Medicine
J Exp Med (2013) 210 (10): 2087–2103.
https://doi.org/10.1084/jem.20122143
Published: 02 September 2013
View article titled, Neuroprotective intervention by interferon-γ blockade prevents CD8<sup>+</sup> T cell–mediated dendrite and synapse loss
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Journal Articles

Autoreactive T cells bypass negative selection and respond to self-antigen stimulation during infection

Sarah Enouz, Lucie Carrié, Doron Merkler, Michael J. Bevan, Dietmar Zehn
Journal: Journal of Experimental Medicine
J Exp Med (2012) 209 (10): 1769–1779.
https://doi.org/10.1084/jem.20120905
Published: 17 September 2012
View article titled, Autoreactive T cells bypass negative selection and respond to self-antigen stimulation during infection
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Journal Articles

Remodeling of Axonal Connections Contributes to Recovery in an Animal Model of Multiple Sclerosis

Martin Kerschensteiner, Florence M. Bareyre, Bigna S. Buddeberg, Doron Merkler, Christine Stadelmann, Wolfgang Brück, Thomas Misgeld, Martin E. Schwab
Journal: Journal of Experimental Medicine
J Exp Med (2004) 200 (8): 1027–1038.
https://doi.org/10.1084/jem.20040452
Published: 18 October 2004
View article titled, Remodeling of Axonal Connections Contributes to Recovery in an Animal Model of Multiple Sclerosis
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Includes: Supplementary data