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Dirk Schmidt-Arras
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Journal Articles

Inhibition of ADAM17 impairs endothelial cell necroptosis and blocks metastasis

Julia Bolik, Freia Krause, Marija Stevanovic, Monja Gandraß, Ilka Thomsen, Sarah-Sophie Schacht, Eva Rieser, Miryam Müller, Neele Schumacher, Jürgen Fritsch, Rielana Wichert, Eithan Galun, Juri Bergmann, Christian Röder, Clemens Schafmayer, Jan-Hendrik Egberts, Christoph Becker-Pauly, Paul Saftig, Ralph Lucius, Wulf Schneider-Brachert, Roja Barikbin, Dieter Adam, Matthias Voss, Wolfgang Hitzl, Achim Krüger, Boris Strilic, Irit Sagi, Henning Walczak, Stefan Rose-John, Dirk Schmidt-Arras
Journal: Journal of Experimental Medicine
J Exp Med (2021) 219 (1): e20201039.
https://doi.org/10.1084/jem.20201039
Published: 17 December 2021
View article titled, Inhibition of ADAM17 impairs endothelial cell necroptosis and blocks metastasis
Open the PDF for Inhibition of ADAM17 impairs endothelial cell necroptosis and blocks metastasis in another window
Includes: Supplementary data
Journal Articles

ADAM17 is required for EGF-R–induced intestinal tumors via IL-6 trans-signaling

Stefanie Schmidt, Neele Schumacher, Jeanette Schwarz, Simone Tangermann, Lukas Kenner, Michaela Schlederer, Maria Sibilia, Markus Linder, Annelore Altendorf-Hofmann, Thomas Knösel, Elisabeth S. Gruber, Georg Oberhuber, Julia Bolik, Ateequr Rehman, Anupam Sinha, Juliane Lokau, Philipp Arnold, Anne-Sophie Cabron, Friederike Zunke, Christoph Becker-Pauly, Adele Preaudet, Paul Nguyen, Jennifer Huynh, Shoukat Afshar-Sterle, Ashwini L. Chand, Jürgen Westermann, Peter J. Dempsey, Christoph Garbers, Dirk Schmidt-Arras, Philip Rosenstiel, Tracy Putoczki, Matthias Ernst, Stefan Rose-John
Journal: Journal of Experimental Medicine
J Exp Med (2018) 215 (4): 1205–1225.
https://doi.org/10.1084/jem.20171696
Published: 22 February 2018
View article titled, ADAM17 is required for EGF-R–induced intestinal tumors via IL-6 trans-signaling
Open the PDF for ADAM17 is required for EGF-R–induced intestinal tumors via IL-6 trans-signaling in another window
Includes: Supplementary data
Journal Articles

A biallelic mutation in IL6ST encoding the GP130 co-receptor causes immunodeficiency and craniosynostosis

Tobias Schwerd, Stephen R.F. Twigg, Dominik Aschenbrenner, Santiago Manrique, Kerry A. Miller, Indira B. Taylor, Melania Capitani, Simon J. McGowan, Elizabeth Sweeney, Astrid Weber, Liye Chen, Paul Bowness, Andrew Riordan, Andrew Cant, Alexandra F. Freeman, Joshua D. Milner, Steven M. Holland, Natalie Frede, Miryam Müller, Dirk Schmidt-Arras, Bodo Grimbacher, Steven A. Wall, E. Yvonne Jones, Andrew O.M. Wilkie, Holm H. Uhlig
Journal: Journal of Experimental Medicine
J Exp Med (2017) 214 (9): 2547–2562.
https://doi.org/10.1084/jem.20161810
Published: 26 July 2017
View article titled, A biallelic mutation in <em>IL6ST</em> encoding the GP130 co-receptor causes immunodeficiency and craniosynostosis
Includes: Supplementary data