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David J. Adams
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Journal Articles

Dominant negative variants in ITPR3 impair T cell Ca2+ dynamics causing combined immunodeficiency

Elena Blanco, Carme Camps, Sameer Bahal, Mohit D. Kerai, Matteo P. Ferla, Adam M. Rochussen, Adam E. Handel, Zainab M. Golwala, Helena Spiridou Goncalves, Susanne Kricke, Fabian Klein, Fang Zhang, Federica Zinghirino, Grace Evans, Thomas M. Keane, Sabrina Lizot, Maaike A.A. Kusters, Mildred A. Iro, Sanjay V. Patel, Emma C. Morris, Siobhan O. Burns, Ruth Radcliffe, Pradeep Vasudevan, Arthur Price, Olivia Gillham, Gabriel E. Valdebenito, Grant S. Stewart, Austen Worth, Stuart P. Adams, Michael Duchen, Isabelle André, David J. Adams, Giorgia Santili, Kimberly C. Gilmour, Georg A. Holländer, E. Graham Davies, Jenny C. Taylor, Gillian M. Griffiths, Adrian J. Thrasher, Fatima Dhalla, Alexandra Y. Kreins
Journal: Journal of Experimental Medicine
J Exp Med (2024) 222 (1): e20220979.
https://doi.org/10.1084/jem.20220979
Published: 19 November 2024
View article titled, Dominant negative variants in <em>ITPR3</em> impair T cell Ca<sup>2+</sup> dynamics causing combined immunodeficiency
Open the PDF for Dominant negative variants in <em>ITPR3</em> impair T cell Ca<sup>2+</sup> dynamics causing combined immunodeficiency in another window
Includes: Supplementary data
Journal Articles

Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity

David C. Thomas, Simon Clare, John M. Sowerby, Mercedes Pardo, Jatinder K. Juss, David A. Goulding, Louise van der Weyden, Daniel Storisteanu, Ananth Prakash, Marion Espéli, Shaun Flint, James C. Lee, Kim Hoenderdos, Leanne Kane, Katherine Harcourt, Subhankar Mukhopadhyay, Yagnesh Umrania, Robin Antrobus, James A. Nathan, David J. Adams, Alex Bateman, Jyoti S. Choudhary, Paul A. Lyons, Alison M. Condliffe, Edwin R. Chilvers, Gordon Dougan, Kenneth G.C. Smith
Journal: Journal of Experimental Medicine
J Exp Med (2017) 214 (4): 1111–1128.
https://doi.org/10.1084/jem.20161382
Published: 28 March 2017
View article titled, Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity
Open the PDF for Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity in another window
Includes: Supplementary data
Journal Articles

A novel mouse model identifies cooperating mutations and therapeutic targets critical for chronic myeloid leukemia progression

George Giotopoulos, Louise van der Weyden, Hikari Osaki, Alistair G. Rust, Paolo Gallipoli, Eshwar Meduri, Sarah J. Horton, Wai-In Chan, Donna Foster, Rab K. Prinjha, John E. Pimanda, Daniel G. Tenen, George S. Vassiliou, Steffen Koschmieder, David J. Adams, Brian J.P. Huntly
Journal: Journal of Experimental Medicine
J Exp Med (2015) 212 (10): 1551–1569.
https://doi.org/10.1084/jem.20141661
Published: 24 August 2015
View article titled, A novel mouse model identifies cooperating mutations and therapeutic targets critical for chronic myeloid leukemia progression
Open the PDF for A novel mouse model identifies cooperating mutations and therapeutic targets critical for chronic myeloid leukemia progression in another window
Includes: Supplementary data