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Christoph Becker
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Journal Articles

Inhibition of ADAM17 impairs endothelial cell necroptosis and blocks metastasis

Julia Bolik, Freia Krause, Marija Stevanovic, Monja Gandraß, Ilka Thomsen, Sarah-Sophie Schacht, Eva Rieser, Miryam Müller, Neele Schumacher, Jürgen Fritsch, Rielana Wichert, Eithan Galun, Juri Bergmann, Christian Röder, Clemens Schafmayer, Jan-Hendrik Egberts, Christoph Becker-Pauly, Paul Saftig, Ralph Lucius, Wulf Schneider-Brachert, Roja Barikbin, Dieter Adam, Matthias Voss, Wolfgang Hitzl, Achim Krüger, Boris Strilic, Irit Sagi, Henning Walczak, Stefan Rose-John, Dirk Schmidt-Arras
Journal: Journal of Experimental Medicine
J Exp Med (2021) 219 (1): e20201039.
https://doi.org/10.1084/jem.20201039
Published: 17 December 2021
View article titled, Inhibition of ADAM17 impairs endothelial cell necroptosis and blocks metastasis
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Includes: Supplementary data
Journal Articles

ADAM17 is required for EGF-R–induced intestinal tumors via IL-6 trans-signaling

Stefanie Schmidt, Neele Schumacher, Jeanette Schwarz, Simone Tangermann, Lukas Kenner, Michaela Schlederer, Maria Sibilia, Markus Linder, Annelore Altendorf-Hofmann, Thomas Knösel, Elisabeth S. Gruber, Georg Oberhuber, Julia Bolik, Ateequr Rehman, Anupam Sinha, Juliane Lokau, Philipp Arnold, Anne-Sophie Cabron, Friederike Zunke, Christoph Becker-Pauly, Adele Preaudet, Paul Nguyen, Jennifer Huynh, Shoukat Afshar-Sterle, Ashwini L. Chand, Jürgen Westermann, Peter J. Dempsey, Christoph Garbers, Dirk Schmidt-Arras, Philip Rosenstiel, Tracy Putoczki, Matthias Ernst, Stefan Rose-John
Journal: Journal of Experimental Medicine
J Exp Med (2018) 215 (4): 1205–1225.
https://doi.org/10.1084/jem.20171696
Published: 22 February 2018
View article titled, ADAM17 is required for EGF-R–induced intestinal tumors via IL-6 trans-signaling
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Includes: Supplementary data
Journal Articles

Regression of apoptosis-resistant colorectal tumors by induction of necroptosis in mice

Gui-Wei He, Claudia Günther, Veronika Thonn, Yu-Qiang Yu, Eva Martini, Barbara Buchen, Markus F. Neurath, Michael Stürzl, Christoph Becker
Journal: Journal of Experimental Medicine
J Exp Med (2017) 214 (6): 1655–1662.
https://doi.org/10.1084/jem.20160442
Published: 05 May 2017
View article titled, Regression of apoptosis-resistant colorectal tumors by induction of necroptosis in mice
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Includes: Supplementary data
Journal Articles

VEGF receptor signaling links inflammation and tumorigenesis in colitis-associated cancer

Maximilian J. Waldner, Stefan Wirtz, André Jefremow, Moritz Warntjen, Clemens Neufert, Raja Atreya, Christoph Becker, Benno Weigmann, Michael Vieth, Stefan Rose-John, Markus F. Neurath
Journal: Journal of Experimental Medicine
J Exp Med (2010) 207 (13): 2855–2868.
https://doi.org/10.1084/jem.20100438
Published: 22 November 2010
View article titled, VEGF receptor signaling links inflammation and tumorigenesis in colitis-associated cancer
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Includes: Supplementary data
Journal Articles

Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice

Athena Chalaris, Nina Adam, Christian Sina, Philip Rosenstiel, Judith Lehmann-Koch, Peter Schirmacher, Dieter Hartmann, Joanna Cichy, Olga Gavrilova, Stefan Schreiber, Thomas Jostock, Vance Matthews, Robert Häsler, Christoph Becker, Markus F. Neurath, Karina Reiß, Paul Saftig, Jürgen Scheller, Stefan Rose-John
Journal: Journal of Experimental Medicine
J Exp Med (2010) 207 (8): 1617–1624.
https://doi.org/10.1084/jem.20092366
Published: 05 July 2010
View article titled, Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice
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Includes: Supplementary data
Journal Articles

STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing

Geethanjali Pickert, Clemens Neufert, Moritz Leppkes, Yan Zheng, Nadine Wittkopf, Moritz Warntjen, Hans-Anton Lehr, Sebastian Hirth, Benno Weigmann, Stefan Wirtz, Wenjun Ouyang, Markus F. Neurath, Christoph Becker
Journal: Journal of Experimental Medicine
J Exp Med (2009) 206 (7): 1465–1472.
https://doi.org/10.1084/jem.20082683
Published: 29 June 2009
View article titled, STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing
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Includes: Supplementary data
Journal Articles

Specific Regulation of T Helper Cell 1–mediated Murine Colitis by CEACAM1

Hideki Iijima, Markus F. Neurath, Takashi Nagaishi, Jonathan N. Glickman, Edward E. Nieuwenhuis, Atsushi Nakajima, Daohong Chen, Ivan J. Fuss, Nalan Utku, Daniel N. Lewicki, Christoph Becker, Thomas M. Gallagher, Kathryn V. Holmes, Richard S. Blumberg
Journal: Journal of Experimental Medicine
J Exp Med (2004) 199 (4): 471–482.
https://doi.org/10.1084/jem.20030437
Published: 17 February 2004
View article titled, Specific Regulation of T Helper Cell 1–mediated Murine Colitis by CEACAM1
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Includes: Supplementary data