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Christian W. Siebel
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Journal Articles

Early Notch signals from fibroblastic reticular cells program effector CD8+ T cell differentiation

In Special Collection:
JEM Immunology Collection 2025
Dave Maurice De Sousa, Eric Perkey, Laure Le Corre, Salix Boulet, Daniela Gómez Atria, Anneka Allman, Frédéric Duval, Jean-François Daudelin, Joshua D. Brandstadter, Katlyn Lederer, Sarah Mezrag, Livia Odagiu, Myriam Ennajimi, Marion Sarrias, Hélène Decaluwe, Ute Koch, Freddy Radtke, Burkhard Ludewig, Christian W. Siebel, Ivan Maillard, Nathalie Labrecque
Journal: Journal of Experimental Medicine
J Exp Med (2025) 222 (5): e20231758.
https://doi.org/10.1084/jem.20231758
Published: 20 March 2025
View articletitled, Early Notch signals from fibroblastic reticular cells program effector CD8+ T cell differentiation
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Includes: Supplementary data
Journal Articles

AKT-dependent NOTCH3 activation drives tumor progression in a model of mesenchymal colorectal cancer

Julia Varga, Adele Nicolas, Valentina Petrocelli, Marina Pesic, Abdelrahman Mahmoud, Birgitta E. Michels, Emre Etlioglu, Diego Yepes, Björn Häupl, Paul K. Ziegler, Katrin Bankov, Peter J. Wild, Stefan Wanninger, Hind Medyouf, Henner F. Farin, Sabine Tejpar, Thomas Oellerich, Jürgen Ruland, Christian W. Siebel, Florian R. Greten
Journal: Journal of Experimental Medicine
J Exp Med (2020) 217 (10): e20191515.
https://doi.org/10.1084/jem.20191515
Published: 04 August 2020
View articletitled, AKT-dependent NOTCH3 activation drives tumor progression in a model of mesenchymal colorectal cancer
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Includes: Supplementary data
Journal Articles

Therapeutic antibody targeting of Notch3 signaling prevents mural cell loss in CADASIL

Arturo I. Machuca-Parra, Alexander A. Bigger-Allen, Angie V. Sanchez, Anissa Boutabla, Jonathan Cardona-Vélez, Dhanesh Amarnani, Magali Saint-Geniez, Christian W. Siebel, Leo A. Kim, Patricia A. D’Amore, Joseph F. Arboleda-Velasquez
Journal: Journal of Experimental Medicine
J Exp Med (2017) 214 (8): 2271–2282.
https://doi.org/10.1084/jem.20161715
Published: 11 July 2017
View articletitled, Therapeutic antibody targeting of Notch3 signaling prevents mural cell loss in CADASIL
Open the PDF for Therapeutic antibody targeting of Notch3 signaling prevents mural cell loss in CADASIL in another window
Includes: Supplementary data
Journal Articles

IRF4 controls the positioning of mature B cells in the lymphoid microenvironments by regulating NOTCH2 expression and activity

Giorgia Simonetti, Amanda Carette, Kathryn Silva, Haowei Wang, Nilushi S. De Silva, Nicole Heise, Christian W. Siebel, Mark J. Shlomchik, Ulf Klein
Journal: Journal of Experimental Medicine
J Exp Med (2013) 210 (13): 2887–2902.
https://doi.org/10.1084/jem.20131026
Published: 09 December 2013
View articletitled, IRF4 controls the positioning of mature B cells in the lymphoid microenvironments by regulating NOTCH2 expression and activity
Open the PDF for IRF4 controls the positioning of mature B cells in the lymphoid microenvironments by regulating NOTCH2 expression and activity in another window
Includes: Supplementary data