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Journal Articles

SARS-CoV-2 brainstem encephalitis in human inherited DBR1 deficiency

Yi-Hao Chan, Vanja Lundberg, Jérémie Le Pen, Jiayi Yuan, Danyel Lee, Francesca Pinci, Stefano Volpi, Koji Nakajima, Vincent Bondet, Sanna Åkesson, Noopur V. Khobrekar, Aaron Bodansky, Likun Du, Tina Melander, Alice-Andrée Mariaggi, Yoann Seeleuthner, Tariq Shikh Saleh, Debanjana Chakravarty, Per Marits, Kerry Dobbs, Sofie Vonlanthen, Viktoria Hennings, Karolina Thörn, Darawan Rinchai, Lucy Bizien, Matthieu Chaldebas, Ali Sobh, Tayfun Özçelik, Sevgi Keles, Suzan A. AlKhater, Carolina Prando, Isabelle Meyts, COVID Human Genetic Effort, Michael R. Wilson, Jérémie Rosain, Emmanuelle Jouanguy, Mélodie Aubart, Laurent Abel, Trine H. Mogensen, Qiang Pan-Hammarström, Daxing Gao, Darragh Duffy, Aurélie Cobat, Stefan Berg, Luigi D. Notarangelo, Oliver Harschnitz, Charles M. Rice, Lorenz Studer, Jean-Laurent Casanova, Olov Ekwall, Shen-Ying Zhang

J Exp Med (2024) 221 (9): e20231725.

https://doi.org/10.1084/jem.20231725

Published: 18 July 2024

View article titled, SARS-CoV-2 brainstem encephalitis in human inherited DBR1 deficiency

Includes: Supplementary data

Journal Articles

Autoantibodies neutralizing type I IFNs underlie West Nile virus encephalitis in ∼40% of patients

In Special Collection:

Cytokines Collection 2023

Adrian Gervais, Francesca Rovida, Maria Antonietta Avanzini, Stefania Croce, Astrid Marchal, Shih-Ching Lin, Alessandro Ferrari, Christian W. Thorball, Orianne Constant, Tom Le Voyer, Quentin Philippot, Jérémie Rosain, Micol Angelini, Malena Pérez Lorenzo, Lucy Bizien, Cristian Achille, Francesca Trespidi, Elisa Burdino, Irene Cassaniti, Daniele Lilleri, Chiara Fornara, José Camilla Sammartino, Danilo Cereda, Chiara Marrocu, Antonio Piralla, Chiara Valsecchi, Stefano Ricagno, Paola Cogo, Olaf Neth, Inés Marín-Cruz, Monia Pacenti, Alessandro Sinigaglia, Marta Trevisan, Andrea Volpe, Antonio Marzollo, Francesca Conti, Tiziana Lazzarotto, Andrea Pession, Pierluigi Viale, Jacques Fellay, Stefano Ghirardello, Mélodie Aubart, Valeria Ghisetti, Alessandro Aiuti, Emmanuelle Jouanguy, Paul Bastard, Elena Percivalle, Fausto Baldanti, Anne Puel, Margaret R. MacDonald, Charles M. Rice, Giada Rossini, Kristy O. Murray, Yannick Simonin, Anna Nagy, Luisa Barzon, Laurent Abel, Michael S. Diamond, Aurélie Cobat, Shen-Ying Zhang, Jean-Laurent Casanova, Alessandro Borghesi

J Exp Med (2023) 220 (9): e20230661.

https://doi.org/10.1084/jem.20230661

Published: 22 June 2023

View article titled, Autoantibodies neutralizing type I IFNs underlie West Nile virus encephalitis in ∼40% of patients

Journal Articles

OX40L-expressing recombinant modified vaccinia virus Ankara induces potent antitumor immunity via reprogramming Tregs

In Special Collection:

Tumor Microenvironment and Metastasis 2023 , Cancer Immunotherapy Update 2024 , JEM Clinical Immunology Collection 2023

Ning Yang, Yi Wang, Shuaitong Liu, Shanza Baseer Tariq, Joseph M. Luna, Gregory Mazo, Adrian Tan, Tuo Zhang, Jiahu Wang, Wei Yan, John Choi, Anthony Rossi, Jenny Zhaoying Xiang, Charles M. Rice, Taha Merghoub, Jedd D. Wolchok, Liang Deng

J Exp Med (2023) 220 (8): e20221166.

https://doi.org/10.1084/jem.20221166

Published: 05 May 2023

View article titled, OX40L-expressing recombinant modified vaccinia virus Ankara induces potent antitumor immunity via reprogramming Tregs

Includes: Supplementary data

Journal Articles

Recessive inborn errors of type I IFN immunity in children with COVID-19 pneumonia

In Special Collection:

Cytokines Collection 2022

J Exp Med (2022) 219 (8): e20220131.

https://doi.org/10.1084/jem.20220131

Published: 16 June 2022

View article titled, Recessive inborn errors of type I IFN immunity in children with COVID-19 pneumonia

Journal Articles

Broad and potent neutralizing human antibodies to tick-borne flaviviruses protect mice from disease

J Exp Med (2021) 218 (5): e20210236.

https://doi.org/10.1084/jem.20210236

Published: 08 April 2021

View article titled, Broad and potent neutralizing human antibodies to tick-borne flaviviruses protect mice from disease

Includes: Supplementary data

Journal Articles

Auto-antibodies to type I IFNs can underlie adverse reactions to yellow fever live attenuated vaccine

In Special Collection:

Antibodies at the Forefront of Disease Treatment , JEM Clinical Immunology Collection 2021

J Exp Med (2021) 218 (4): e20202486.

https://doi.org/10.1084/jem.20202486

Published: 05 February 2021

View article titled, Auto-antibodies to type I IFNs can underlie adverse reactions to yellow fever live attenuated vaccine

Includes: Supplementary data

Journal Articles

Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses

In Special Collection:

2020 Nobel Prize Collection , 2020: The Year in Experimental Medicine , COVID-19: From Basic Science to Therapeutics , JEM Immunology Collection 2021

J Exp Med (2020) 217 (11): e20201181.

https://doi.org/10.1084/jem.20201181

Published: 21 July 2020

View article titled, Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses

Includes: Supplementary data

Journal Articles

Risk of Zika microcephaly correlates with features of maternal antibodies

In Special Collection:

2019: The Year in Experimental Medicine , Vaccines: HIV and Beyond

Davide F. Robbiani, Priscilla C. Olsen, Federico Costa, Qiao Wang, Thiago Y. Oliveira, Nivison Nery, Jr., Adeolu Aromolaran, Mateus S. do Rosário, Gielson A. Sacramento, Jaqueline S. Cruz, Ricardo Khouri, Elsio A. Wunder, Jr., Adriana Mattos, Bruno de Paula Freitas, Manoel Sarno, Gracinda Archanjo, Dina Daltro, Gustavo B.S. Carvalho, Kleber Pimentel, Isadora C. de Siqueira, João R.M. de Almeida, Daniele F. Henriques, Juliana A. Lima, Pedro F.C. Vasconcelos, Dennis Schaefer-Babajew, Stephanie A. Azzopardi, Leonia Bozzacco, Anna Gazumyan, Rubens Belfort, Jr., Ana P. Alcântara, Gustavo Carvalho, Licia Moreira, Katiaci Araujo, Mitermayer G. Reis, Rebekah I. Keesler, Lark L. Coffey, Jennifer Tisoncik-Go, Michael Gale, Jr., Lakshmi Rajagopal, Kristina M. Adams Waldorf, Dawn M. Dudley, Heather A. Simmons, Andres Mejia, David H. O’Connor, Rosemary J. Steinbach, Nicole Haese, Jessica Smith, Anne Lewis, Lois Colgin, Victoria Roberts, Antonio Frias, Meredith Kelleher, Alec Hirsch, Daniel N. Streblow, Charles M. Rice, Margaret R. MacDonald, Antonio R.P. de Almeida, Koen K.A. Van Rompay, Albert I. Ko, Michel C. Nussenzweig

J Exp Med (2019) 216 (10): 2302–2315.

https://doi.org/10.1084/jem.20191061

Published: 14 August 2019

View article titled, Risk of Zika microcephaly correlates with features of maternal antibodies

Includes: Supplementary data

Journal Articles

Inherited IFNAR1 deficiency in otherwise healthy patients with adverse reaction to measles and yellow fever live vaccines

In Special Collection:

2020 Nobel Prize Collection

Nicholas Hernandez, Giorgia Bucciol, Leen Moens, Jérémie Le Pen, Mohammad Shahrooei, Ekaterini Goudouris, Afshin Shirkani, Majid Changi-Ashtiani, Hassan Rokni-Zadeh, Esra Hazar Sayar, Ismail Reisli, Alain Lefevre-Utile, Dick Zijlmans, Andrea Jurado, Ruben Pholien, Scott Drutman, Serkan Belkaya, Aurelie Cobat, Robbert Boudewijns, Dirk Jochmans, Johan Neyts, Yoann Seeleuthner, Lazaro Lorenzo-Diaz, Chibuzo Enemchukwu, Ian Tietjen, Hans-Heinrich Hoffmann, Mana Momenilandi, Laura Pöyhönen, Marilda M. Siqueira, Sheila M. Barbosa de Lima, Denise C. de Souza Matos, Akira Homma, Maria de Lourdes S. Maia, Tamiris Azamor da Costa Barros, Patricia Mouta Nunes de Oliveira, Emersom Ciclini Mesquita, Rik Gijsbers, Shen-Ying Zhang, Stephen J. Seligman, Laurent Abel, Paul Hertzog, Nico Marr, Reinaldo de Menezes Martins, Isabelle Meyts, Qian Zhang, Margaret R. MacDonald, Charles M. Rice, Jean-Laurent Casanova, Emmanuelle Jouanguy, Xavier Bossuyt

J Exp Med (2019) 216 (9): 2057–2070.

https://doi.org/10.1084/jem.20182295

Published: 03 July 2019

View article titled, Inherited IFNAR1 deficiency in otherwise healthy patients with adverse reaction to measles and yellow fever live vaccines

Includes: Supplementary data

Journal Articles

Inherited IL-18BP deficiency in human fulminant viral hepatitis

In Special Collection:

2020 Nobel Prize Collection , Clinical Collection Summer 2019 , JEM Immunology Collection 2020

J Exp Med (2019) 216 (8): 1777–1790.

https://doi.org/10.1084/jem.20190669

Published: 18 June 2019

View article titled, Inherited IL-18BP deficiency in human fulminant viral hepatitis

Includes: Supplementary data

Journal Articles

Interferon regulatory factor 2 protects mice from lethal viral neuroinvasion

Melody M.H. Li, Leonia Bozzacco, Hans-Heinrich Hoffmann, Gaëlle Breton, Jakob Loschko, Jing W. Xiao, Sébastien Monette, Charles M. Rice, Margaret R. MacDonald

J Exp Med (2016) 213 (13): 2931–2947.

https://doi.org/10.1084/jem.20160303

Published: 29 November 2016

View article titled, Interferon regulatory factor 2 protects mice from lethal viral neuroinvasion

Includes: Supplementary data

Journal Articles

Histone H3 lysine 9 di-methylation as an epigenetic signature of the interferon response

Terry C. Fang, Uwe Schaefer, Ingrid Mecklenbrauker, Astrid Stienen, Scott Dewell, Marie S. Chen, Inmaculada Rioja, Valentino Parravicini, Rab K. Prinjha, Rohit Chandwani, Margaret R. MacDonald, Kevin Lee, Charles M. Rice, Alexander Tarakhovsky

J Exp Med (2012) 209 (4): 661–669.

https://doi.org/10.1084/jem.20112343

Published: 12 March 2012

View article titled, Histone H3 lysine 9 di-methylation as an epigenetic signature of the interferon response

Includes: Supplementary data

Journal Articles

Priming of protective T cell responses against virus-induced tumors in mice with human immune system components

Till Strowig, Cagan Gurer, Alexander Ploss, Yi-Fang Liu, Frida Arrey, Junji Sashihara, Gloria Koo, Charles M. Rice, James W. Young, Amy Chadburn, Jeffrey I. Cohen, Christian Münz

J Exp Med (2009) 206 (6): 1423–1434.

https://doi.org/10.1084/jem.20081720

Published: 01 June 2009

View article titled, Priming of protective T cell responses against virus-induced tumors in mice with human immune system components

Includes: Supplementary data

Journal Articles

Plasmacytoid dendritic cells initiate a complex chemokine and cytokine network and are a viable drug target in chronic HCV patients

In Special Collection:

2020 Nobel Prize Collection

Jérémie Decalf, Sandrine Fernandes, Randy Longman, Mina Ahloulay, Françoise Audat, François Lefrerre, Charles M. Rice, Stanislas Pol, Matthew L. Albert

J Exp Med (2007) 204 (10): 2423–2437.

https://doi.org/10.1084/jem.20070814

Published: 24 September 2007

View article titled, Plasmacytoid dendritic cells initiate a complex chemokine and cytokine network and are a viable drug target in chronic HCV patients

Includes: Supplementary data

Journal Articles

Live attenuated yellow fever 17D infects human DCs and allows for presentation of endogenous and recombinant T cell epitopes

In Special Collection:

2020 Nobel Prize Collection

Giovanna Barba-Spaeth, Randy S. Longman, Matthew L. Albert, Charles M. Rice

J Exp Med (2005) 202 (9): 1179–1184.

https://doi.org/10.1084/jem.20051352

Published: 31 October 2005

View article titled, Live attenuated yellow fever 17D infects human DCs and allows for presentation of endogenous and recombinant T cell epitopes

Includes: Supplementary data

Journal Articles

Yellow fever 17D as a vaccine vector for microbial CTL epitopes : protection in a rodent malaria model

In Special Collection:

2020 Nobel Prize Collection

Deng Tao, Giovanna Barba-Spaeth, Urvashi Rai, Victor Nussenzweig, Charles M. Rice, Ruth S. Nussenzweig

J Exp Med (2005) 201 (2): 201–209.

https://doi.org/10.1084/jem.20041526

Published: 18 January 2005

View article titled, Yellow fever 17D as a vaccine vector for microbial CTL epitopes : <subtitle>protection in a rodent malaria model </subtitle>

NARROW

SARS-CoV-2 brainstem encephalitis in human inherited DBR1 deficiency

Autoantibodies neutralizing type I IFNs underlie West Nile virus encephalitis in ∼40% of patients

OX40L-expressing recombinant modified vaccinia virus Ankara induces potent antitumor immunity via reprogramming Tregs

Recessive inborn errors of type I IFN immunity in children with COVID-19 pneumonia

Broad and potent neutralizing human antibodies to tick-borne flaviviruses protect mice from disease

Auto-antibodies to type I IFNs can underlie adverse reactions to yellow fever live attenuated vaccine

Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses

Risk of Zika microcephaly correlates with features of maternal antibodies

Inherited IFNAR1 deficiency in otherwise healthy patients with adverse reaction to measles and yellow fever live vaccines

Inherited IL-18BP deficiency in human fulminant viral hepatitis

Interferon regulatory factor 2 protects mice from lethal viral neuroinvasion

Histone H3 lysine 9 di-methylation as an epigenetic signature of the interferon response

Priming of protective T cell responses against virus-induced tumors in mice with human immune system components

Plasmacytoid dendritic cells initiate a complex chemokine and cytokine network and are a viable drug target in chronic HCV patients

Live attenuated yellow fever 17D infects human DCs and allows for presentation of endogenous and recombinant T cell epitopes

Yellow fever 17D as a vaccine vector for microbial CTL epitopes : protection in a rodent malaria model

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