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Charles G. Mullighan
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Journal Articles

Native stem cell transcriptional circuits define cardinal features of high-risk leukemia

Qing Wang, Francesco Boccalatte, Jason Xu, Giovanni Gambi, Bettina Nadorp, Fatema Akter, Carea Mullin, Ashley F. Melnick, Elizabeth Choe, Anna C. McCarter, Nicole A. Jerome, Siyi Chen, Karena Lin, Sarah Khan, Rohan Kodgule, Jonathan H. Sussman, Petri Pölönen, Javier Rodriguez-Hernaez, Sonali Narang, Kleopatra Avrampou, Bryan King, Aristotelis Tsirigos, Russell J.H. Ryan, Charles G. Mullighan, David T. Teachey, Kai Tan, Iannis Aifantis, Mark Y. Chiang
Journal: Journal of Experimental Medicine
J Exp Med (2025) 222 (4): e20231349.
https://doi.org/10.1084/jem.20231349
Published: 19 February 2025
View articletitled, Native stem cell transcriptional circuits define cardinal features of high-risk leukemia
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Includes: Supplementary data
Journal Articles

Conserved IKAROS-regulated genes associated with B-progenitor acute lymphoblastic leukemia outcome

Matthew T. Witkowski, Yifang Hu, Kathryn G. Roberts, Judith M. Boer, Mark D. McKenzie, Grace J. Liu, Oliver D. Le Grice, Cedric S. Tremblay, Margherita Ghisi, Tracy A. Willson, Martin A. Horstmann, Iannis Aifantis, Luisa Cimmino, Seth Frietze, Monique L. den Boer, Charles G. Mullighan, Gordon K. Smyth, Ross A. Dickins
Journal: Journal of Experimental Medicine
J Exp Med (2017) 214 (3): 773–791.
https://doi.org/10.1084/jem.20160048
Published: 11 February 2017
View articletitled, Conserved IKAROS-regulated genes associated with B-progenitor acute lymphoblastic leukemia outcome
Open the PDF for Conserved IKAROS-regulated genes associated with B-progenitor acute lymphoblastic leukemia outcome in another window
Includes: Supplementary data
Journal Articles

Interleukin-7 receptor mutants initiate early T cell precursor leukemia in murine thymocyte progenitors with multipotent potential

Louise M. Treanor, Sheng Zhou, Laura Janke, Michelle L. Churchman, Zhijun Ma, Taihe Lu, Shann-Ching Chen, Charles G. Mullighan, Brian P. Sorrentino
Journal: Journal of Experimental Medicine
J Exp Med (2014) 211 (4): 701–713.
https://doi.org/10.1084/jem.20122727
Published: 31 March 2014
View articletitled, Interleukin-7 receptor mutants initiate early T cell precursor leukemia in murine thymocyte progenitors with multipotent potential
Open the PDF for Interleukin-7 receptor mutants initiate early T cell precursor leukemia in murine thymocyte progenitors with multipotent potential in another window
Journal Articles

Genetic lesions associated with chronic lymphocytic leukemia transformation to Richter syndrome

Giulia Fabbri, Hossein Khiabanian, Antony B. Holmes, Jiguang Wang, Monica Messina, Charles G. Mullighan, Laura Pasqualucci, Raul Rabadan, Riccardo Dalla-Favera
Journal: Journal of Experimental Medicine
J Exp Med (2013) 210 (11): 2273–2288.
https://doi.org/10.1084/jem.20131448
Published: 14 October 2013
View articletitled, Genetic lesions associated with chronic lymphocytic leukemia transformation to Richter syndrome
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Includes: Supplementary data
Journal Articles

Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation

Giulia Fabbri, Silvia Rasi, Davide Rossi, Vladimir Trifonov, Hossein Khiabanian, Jing Ma, Adina Grunn, Marco Fangazio, Daniela Capello, Sara Monti, Stefania Cresta, Ernesto Gargiulo, Francesco Forconi, Anna Guarini, Luca Arcaini, Marco Paulli, Luca Laurenti, Luigi M. Larocca, Roberto Marasca, Valter Gattei, David Oscier, Francesco Bertoni, Charles G. Mullighan, Robin Foá, Laura Pasqualucci, Raul Rabadan, Riccardo Dalla-Favera, Gianluca Gaidano
Journal: Journal of Experimental Medicine
J Exp Med (2011) 208 (7): 1389–1401.
https://doi.org/10.1084/jem.20110921
Published: 13 June 2011
View articletitled, Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation
Open the PDF for Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation in another window
Includes: Supplementary data