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Journal Articles

Defective LAT signalosome pathology in mice mimics human IgG4-related disease at single-cell level

Anais Joachim, Rudy Aussel, Léna Gélard, Fanghui Zhang, Daiki Mori, Claude Grégoire, Sergio Villazala Merino, Mauro Gaya, Yinming Liang, Marie Malissen, Bernard Malissen

J Exp Med (2023) 220 (11): e20231028.

https://doi.org/10.1084/jem.20231028

Published: 25 August 2023

View article titled, Defective LAT signalosome pathology in mice mimics human IgG4-related disease at single-cell level

Includes: Supplementary data

Journal Articles

Human CARMIL2 deficiency underlies a broader immunological and clinical phenotype than CD28 deficiency

Romain Lévy, Florian Gothe, Mana Momenilandi, Thomas Magg, Marie Materna, Philipp Peters, Johannes Raedler, Quentin Philippot, Anita Lena Rack-Hoch, David Langlais, Mathieu Bourgey, Anna-Lisa Lanz, Masato Ogishi, Jérémie Rosain, Emmanuel Martin, Sylvain Latour, Natasha Vladikine, Marco Distefano, Taushif Khan, Franck Rapaport, Marian S. Schulz, Ursula Holzer, Anders Fasth, Georgios Sogkas, Carsten Speckmann, Arianna Troilo, Venetia Bigley, Anna Roppelt, Yael Dinur-Schejter, Ori Toker, Karen Helene Bronken Martinsen, Roya Sherkat, Ido Somekh, Raz Somech, Dror S. Shouval, Jörn-Sven Kühl, Winnie Ip, Elizabeth M. McDermott, Lucy Cliffe, Ahmet Ozen, Safa Baris, Hemalatha G. Rangarajan, Emmanuelle Jouanguy, Anne Puel, Jacinta Bustamante, Marie-Alexandra Alyanakian, Mathieu Fusaro, Yi Wang, Xiao-Fei Kong, Aurélie Cobat, David Boutboul, Martin Castelle, Claire Aguilar, Olivier Hermine, Morgane Cheminant, Felipe Suarez, Alisan Yildiran, Aziz Bousfiha, Hamoud Al-Mousa, Fahad Alsohime, Deniz Cagdas, Roshini S. Abraham, Alan P. Knutsen, Borre Fevang, Sagar Bhattad, Ayca Kiykim, Baran Erman, Tugba Arikoglu, Ekrem Unal, Ashish Kumar, Christoph B. Geier, Ulrich Baumann, Bénédicte Neven, CARMIL2 Consortium, Meino Rohlfs, Christoph Walz, Laurent Abel, Bernard Malissen, Nico Marr, Christoph Klein, Jean-Laurent Casanova, Fabian Hauck, Vivien Béziat

J Exp Med (2022) 220 (2): e20220275.

https://doi.org/10.1084/jem.20220275

Published: 14 December 2022

View article titled, Human CARMIL2 deficiency underlies a broader immunological and clinical phenotype than CD28 deficiency

Includes: Supplementary data

Journal Articles

Systems-level conservation of the proximal TCR signaling network of mice and humans

Philippe Nicolas, Jocelyn Ollier, Daiki Mori, Guillaume Voisinne, Javier Celis-Gutierrez, Claude Gregoire, Jeanne Perroteau, Régine Vivien, Mylène Camus, Odile Burlet-Schiltz, Anne Gonzalez de Peredo, Béatrice Clémenceau, Romain Roncagalli, Henri Vié, Bernard Malissen

J Exp Med (2022) 219 (2): e20211295.

https://doi.org/10.1084/jem.20211295

Published: 21 January 2022

View article titled, Systems-level conservation of the proximal TCR signaling network of mice and humans

Includes: Supplementary data

Journal Articles

The T cell CD6 receptor operates a multitask signalosome with opposite functions in T cell activation

Daiki Mori, Claude Grégoire, Guillaume Voisinne, Javier Celis-Gutierrez, Rudy Aussel, Laura Girard, Mylène Camus, Marlène Marcellin, Jérémy Argenty, Odile Burlet-Schiltz, Frédéric Fiore, Anne Gonzalez de Peredo, Marie Malissen, Romain Roncagalli, Bernard Malissen

J Exp Med (2020) 218 (2): e20201011.

https://doi.org/10.1084/jem.20201011

Published: 30 October 2020

View article titled, The T cell CD6 receptor operates a multitask signalosome with opposite functions in T cell activation

Includes: Supplementary data

Journal Articles

Unveiling skin macrophage dynamics explains both tattoo persistence and strenuous removal

In Special Collection:

2018: The Year in Experimental Medicine , Myeloid Cells 2019 , Skin Health and Disease

Anna Baranska, Alaa Shawket, Mabel Jouve, Myriam Baratin, Camille Malosse, Odessa Voluzan, Thien-Phong Vu Manh, Frédéric Fiore, Marc Bajénoff, Philippe Benaroch, Marc Dalod, Marie Malissen, Sandrine Henri, Bernard Malissen

J Exp Med (2018) 215 (4): 1115–1133.

https://doi.org/10.1084/jem.20171608

Published: 06 March 2018

View article titled, Unveiling skin macrophage dynamics explains both tattoo persistence and strenuous removal

Includes: Supplementary data

Journal Articles

Dual T cell– and B cell–intrinsic deficiency in humans with biallelic RLTPR mutations

In Special Collection:

Monogenic Auto-Inflammation and Auto-Immunity in Humans 2018

J Exp Med (2016) 213 (11): 2413–2435.

https://doi.org/10.1084/jem.20160576

Published: 19 September 2016

View article titled, Dual T cell– and B cell–intrinsic deficiency in humans with biallelic RLTPR mutations

Includes: Supplementary data

Journal Articles

The scaffolding function of the RLTPR protein explains its essential role for CD28 co-stimulation in mouse and human T cells

Romain Roncagalli, Margot Cucchetti, Nicolas Jarmuzynski, Claude Grégoire, Elise Bergot, Stéphane Audebert, Emilie Baudelet, Marisa Goncalves Menoita, Anais Joachim, Stéphane Durand, Miloslav Suchanek, Frédéric Fiore, Lichen Zhang, Yinming Liang, Luc Camoin, Marie Malissen, Bernard Malissen

J Exp Med (2016) 213 (11): 2437–2457.

https://doi.org/10.1084/jem.20160579

Published: 19 September 2016

View article titled, The scaffolding function of the RLTPR protein explains its essential role for CD28 co-stimulation in mouse and human T cells

Includes: Supplementary data

Journal Articles

CD6 modulates thymocyte selection and peripheral T cell homeostasis

Marc Orta-Mascaró, Marta Consuegra-Fernández, Esther Carreras, Romain Roncagalli, Amado Carreras-Sureda, Pilar Alvarez, Laura Girard, Inês Simões, Mario Martínez-Florensa, Fernando Aranda, Ramón Merino, Vanesa-Gabriela Martínez, Rubén Vicente, Jesús Merino, Adelaida Sarukhan, Marie Malissen, Bernard Malissen, Francisco Lozano

J Exp Med (2016) 213 (8): 1387–1397.

https://doi.org/10.1084/jem.20151785

Published: 04 July 2016

View article titled, CD6 modulates thymocyte selection and peripheral T cell homeostasis

Journal Articles

Progressive replacement of embryo-derived cardiac macrophages with age

Kaaweh Molawi, Yochai Wolf, Prashanth K. Kandalla, Jeremy Favret, Nora Hagemeyer, Kathrin Frenzel, Alexander R. Pinto, Kay Klapproth, Sandrine Henri, Bernard Malissen, Hans-Reimer Rodewald, Nadia A. Rosenthal, Marc Bajenoff, Marco Prinz, Steffen Jung, Michael H. Sieweke

J Exp Med (2014) 211 (11): 2151–2158.

https://doi.org/10.1084/jem.20140639

Published: 22 September 2014

View article titled, Progressive replacement of embryo-derived cardiac macrophages with age

Includes: Supplementary data

Journal Articles

Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF

Martin Guilliams, Ismé De Kleer, Sandrine Henri, Sijranke Post, Leen Vanhoutte, Sofie De Prijck, Kim Deswarte, Bernard Malissen, Hamida Hammad, Bart N. Lambrecht

J Exp Med (2013) 210 (10): 1977–1992.

https://doi.org/10.1084/jem.20131199

Published: 16 September 2013

View article titled, Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF

Journal Articles

Multicolor fate mapping of Langerhans cell homeostasis

Clément Ghigo, Isabelle Mondor, Audrey Jorquera, Jonathan Nowak, Stephan Wienert, Sonja P. Zahner, Björn E. Clausen, Hervé Luche, Bernard Malissen, Frederick Klauschen, Marc Bajénoff

J Exp Med (2013) 210 (9): 1657–1664.

https://doi.org/10.1084/jem.20130403

Published: 12 August 2013

View article titled, Multicolor fate mapping of Langerhans cell homeostasis

Includes: Supplementary data

Journal Articles

Neutrophil depletion impairs natural killer cell maturation, function, and homeostasis

Baptiste N. Jaeger, Jean Donadieu, Céline Cognet, Claire Bernat, Diana Ordoñez-Rueda, Vincent Barlogis, Nizar Mahlaoui, Aurore Fenis, Emilie Narni-Mancinelli, Blandine Beaupain, Christine Bellanné-Chantelot, Marc Bajénoff, Bernard Malissen, Marie Malissen, Eric Vivier, Sophie Ugolini

J Exp Med (2012) 209 (3): 565–580.

https://doi.org/10.1084/jem.20111908

Published: 05 March 2012

View article titled, Neutrophil depletion impairs natural killer cell maturation, function, and homeostasis

Journal Articles

Thymus-specific serine protease contributes to the diversification of the functional endogenous CD4 T cell receptor repertoire

Christophe Viret, Camille Lamare, Martine Guiraud, Nicolas Fazilleau, Agathe Bour, Bernard Malissen, Alice Carrier, Sylvie Guerder

J Exp Med (2010) 208 (1): 3–11.

https://doi.org/10.1084/jem.20100027

Published: 20 December 2010

View article titled, Thymus-specific serine protease contributes to the diversification of the functional endogenous CD4 T cell receptor repertoire

Includes: Supplementary data

Journal Articles

CD207⁺ CD103⁺ dermal dendritic cells cross-present keratinocyte-derived antigens irrespective of the presence of Langerhans cells

Sandrine Henri, Lionel Franz Poulin, Samira Tamoutounour, Laurence Ardouin, Martin Guilliams, Béatrice de Bovis, Elisabeth Devilard, Christophe Viret, Hiroaki Azukizawa, Adrien Kissenpfennig, Bernard Malissen

J Exp Med (2010) 207 (2): 447.

https://doi.org/10.1084/jem.2009196412910c

Published: 08 February 2010

View article titled, CD207+ CD103+ dermal dendritic cells cross-present keratinocyte-derived antigens irrespective of the presence of Langerhans cells

Journal Articles

CD207⁺ CD103⁺ dermal dendritic cells cross-present keratinocyte-derived antigens irrespective of the presence of Langerhans cells

J Exp Med (2009) 207 (1): 189–206.

https://doi.org/10.1084/jem.20091964

Published: 28 December 2009

View article titled, CD207+ CD103+ dermal dendritic cells cross-present keratinocyte-derived antigens irrespective of the presence of Langerhans cells

Includes: Supplementary data

Journal Articles

Langerhans cell (LC) proliferation mediates neonatal development, homeostasis, and inflammation-associated expansion of the epidermal LC network

Laurent Chorro, Aurélien Sarde, Mei Li, Kevin J. Woollard, Pierre Chambon, Bernard Malissen, Adrien Kissenpfennig, Jean-Baptiste Barbaroux, Richard Groves, Frédéric Geissmann

J Exp Med (2009) 206 (13): 3089–3100.

https://doi.org/10.1084/jem.20091586

Published: 07 December 2009

View article titled, Langerhans cell (LC) proliferation mediates neonatal development, homeostasis, and inflammation-associated expansion of the epidermal LC network

Includes: Supplementary data

Journal Articles

Identification of a novel population of Langerin⁺ dendritic cells

Laura S. Bursch, Liangchun Wang, Botond Igyarto, Adrien Kissenpfennig, Bernard Malissen, Daniel H. Kaplan, Kristin A. Hogquist

J Exp Med (2007) 204 (13): 3147–3156.

https://doi.org/10.1084/jem.20071966

Published: 17 December 2007

View article titled, Identification of a novel population of Langerin+ dendritic cells

Includes: Supplementary data

Journal Articles

The dermis contains langerin⁺ dendritic cells that develop and function independently of epidermal Langerhans cells

Lionel Franz Poulin, Sandrine Henri, Béatrice de Bovis, Elisabeth Devilard, Adrien Kissenpfennig, Bernard Malissen

J Exp Med (2007) 204 (13): 3119–3131.

https://doi.org/10.1084/jem.20071724

Published: 17 December 2007

View article titled, The dermis contains langerin+ dendritic cells that develop and function independently of epidermal Langerhans cells

Includes: Supplementary data

Journal Articles

Blood-derived dermal langerin⁺ dendritic cells survey the skin in the steady state

Florent Ginhoux, Matthew P. Collin, Milena Bogunovic, Michal Abel, Marylene Leboeuf, Julie Helft, Jordi Ochando, Adrien Kissenpfennig, Bernard Malissen, Marcos Grisotto, Hans Snoeck, Gwendalyn Randolph, Miriam Merad

J Exp Med (2007) 204 (13): 3133–3146.

https://doi.org/10.1084/jem.20071733

Published: 17 December 2007

View article titled, Blood-derived dermal langerin+ dendritic cells survey the skin in the steady state

Includes: Supplementary data

Journal Articles

Negative Regulation of Mast Cell Signaling and Function by the Adaptor LAB/NTAL

Petra Volná, Pavel Lebduška, Lubica Dráberová, Šárka Šímová, Petr Heneberg, Michael Boubelík, Viktor Bugajev, Bernard Malissen, Bridget S. Wilson, Václav Hořejší, Marie Malissen, Petr Dráber

J Exp Med (2004) 200 (8): 1001–1014.

https://doi.org/10.1084/jem.20041213

Published: 11 October 2004

View article titled, Negative Regulation of Mast Cell Signaling and Function by the Adaptor LAB/NTAL

NARROW

Defective LAT signalosome pathology in mice mimics human IgG4-related disease at single-cell level

Human CARMIL2 deficiency underlies a broader immunological and clinical phenotype than CD28 deficiency

Systems-level conservation of the proximal TCR signaling network of mice and humans

The T cell CD6 receptor operates a multitask signalosome with opposite functions in T cell activation

Unveiling skin macrophage dynamics explains both tattoo persistence and strenuous removal

Dual T cell– and B cell–intrinsic deficiency in humans with biallelic RLTPR mutations

The scaffolding function of the RLTPR protein explains its essential role for CD28 co-stimulation in mouse and human T cells

CD6 modulates thymocyte selection and peripheral T cell homeostasis

Progressive replacement of embryo-derived cardiac macrophages with age

Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF

Multicolor fate mapping of Langerhans cell homeostasis

Neutrophil depletion impairs natural killer cell maturation, function, and homeostasis

Thymus-specific serine protease contributes to the diversification of the functional endogenous CD4 T cell receptor repertoire

CD207⁺ CD103⁺ dermal dendritic cells cross-present keratinocyte-derived antigens irrespective of the presence of Langerhans cells

CD207⁺ CD103⁺ dermal dendritic cells cross-present keratinocyte-derived antigens irrespective of the presence of Langerhans cells

Langerhans cell (LC) proliferation mediates neonatal development, homeostasis, and inflammation-associated expansion of the epidermal LC network

Identification of a novel population of Langerin⁺ dendritic cells

The dermis contains langerin⁺ dendritic cells that develop and function independently of epidermal Langerhans cells

Blood-derived dermal langerin⁺ dendritic cells survey the skin in the steady state

Negative Regulation of Mast Cell Signaling and Function by the Adaptor LAB/NTAL

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