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Nucleotide modifications enable rational design of TLR7-selective ligands by blocking RNase cleavage

In Special Collection:

JEM Immunology Collection 2024 , Immunology Update Winter 2024 , Innate Immune Signaling: From Host Defense to Disease Pathogenesis

Ann-Jay Tong, Rebecca Leylek, Anna-Maria Herzner, Diamanda Rigas, Sara Wichner, Craig Blanchette, Siri Tahtinen, Christopher C. Kemball, Ira Mellman, Benjamin Haley, Emily C. Freund, Lélia Delamarre

J Exp Med (2023) 221 (2): e20230341.

https://doi.org/10.1084/jem.20230341

Published: 14 December 2023

View article titled, Nucleotide modifications enable rational design of TLR7-selective ligands by blocking RNase cleavage

Includes: Supplementary data

Journal Articles

High-efficiency nonviral CRISPR/Cas9-mediated gene editing of human T cells using plasmid donor DNA

Soyoung A. Oh, Kate Senger, Shravan Madireddi, Ilseyar Akhmetzyanova, Isabel E. Ishizuka, Somayeh Tarighat, Jerry H. Lo, David Shaw, Benjamin Haley, Sascha Rutz

J Exp Med (2022) 219 (5): e20211530.

https://doi.org/10.1084/jem.20211530

Published: 22 April 2022

View article titled, High-efficiency nonviral CRISPR/Cas9-mediated gene editing of human T cells using plasmid donor DNA

Includes: Supplementary data

Journal Articles

ADAR and hnRNPC deficiency synergize in activating endogenous dsRNA-induced type I IFN responses

Anna-Maria Herzner, Zia Khan, Eric L. Van Nostrand, Sara Chan, Trinna Cuellar, Ronald Chen, Ximo Pechuan-Jorge, Laszlo Komuves, Margaret Solon, Zora Modrusan, Benjamin Haley, Gene W. Yeo, Timothy W. Behrens, Matthew L. Albert

J Exp Med (2021) 218 (9): e20201833.

https://doi.org/10.1084/jem.20201833

Published: 23 July 2021

View article titled, ADAR and hnRNPC deficiency synergize in activating endogenous dsRNA-induced type I IFN responses

Includes: Supplementary data

Journal Articles

Efficient gene knockout in primary human and murine myeloid cells by non-viral delivery of CRISPR-Cas9

Emily C. Freund, Jaclyn Y. Lock, Jaehak Oh, Timurs Maculins, Lelia Delamarre, Christopher J. Bohlen, Benjamin Haley, Aditya Murthy

J Exp Med (2020) 217 (7): e20191692.

https://doi.org/10.1084/jem.20191692

Published: 01 May 2020

View article titled, Efficient gene knockout in primary human and murine myeloid cells by non-viral delivery of CRISPR-Cas9

Includes: Supplementary data

Journal Articles

Mutation position is an important determinant for predicting cancer neoantigens

In Special Collection:

JEM 2020 Update on Cancer Immunology and Immunotherapy , JEM Cancer Collection 2020 , JEM Cancer Collection 2021

J Exp Med (2020) 217 (4): e20190179.

https://doi.org/10.1084/jem.20190179

Published: 15 January 2020

View article titled, Mutation position is an important determinant for predicting cancer neoantigens

Includes: Supplementary data

NARROW

Nucleotide modifications enable rational design of TLR7-selective ligands by blocking RNase cleavage

High-efficiency nonviral CRISPR/Cas9-mediated gene editing of human T cells using plasmid donor DNA

ADAR and hnRNPC deficiency synergize in activating endogenous dsRNA-induced type I IFN responses

Efficient gene knockout in primary human and murine myeloid cells by non-viral delivery of CRISPR-Cas9

Mutation position is an important determinant for predicting cancer neoantigens

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Nucleotide modifications enable rational design of TLR7-selective ligands by blocking RNase cleavage

High-efficiency nonviral CRISPR/Cas9-mediated gene editing of human T cells using plasmid donor DNA

ADAR and hnRNPC deficiency synergize in activating endogenous dsRNA-induced type I IFN responses

Efficient gene knockout in primary human and murine myeloid cells by non-viral delivery of CRISPR-Cas9

Mutation position is an important determinant for predicting cancer neoantigens

Email alerts

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