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6 April 2026
In Progress
ISSN 0022-1007
EISSN 1540-9538
Article
Zbtb32 promotes CD8+ T cell differentiation and function in cancer
Birui Pan,Qinli Sun,Ruifeng Li,Juan Feng,Jing Hao,Bowen Xie,Xiaohong Zhao,Zixuan Zhao,Peng Wei,Qiuyan Lan,Shiyuan Xie,Tian Xie,Yongzhen Chen,Kun Wei,Xuan Zhong,Hai Qi,Ling Ni,Chen Dong
Birui et al. identify Zbtb32 as a key promoter of terminally exhausted CD8+ T cell differentiation, enhancing cell cytotoxicity and anti-tumor function. This study reveals the potential interplay and regulation within CD8+ T cell regulatory network, providing valuable insights for cancer immunotherapy.
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