ON THE COVER
As shown by Liu et al., B cell receptor (BCR) affinity for antigen is “translated” into alterations in BCR mobility and clustering very early after antigen encounter. Pseudocolored spots represent individual BCRs tracked by total internal reflection fluorescence microscopy. Artwork by Rachel Urkowitz (firstname.lastname@example.org).
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Brief Definitive Report
The fusion kinase ITK-SYK mimics a T cell receptor signal and drives oncogenesis in conditional mouse models of peripheral T cell lymphoma