ON THE COVER
Brief Definitive Reports from the teams of Raulet and Yokoyama illustrate the functional plasticity of mature NK cells. Dysfunctional NK cells from MHC class I–deficient mice gain effector function when transferred to MHC-sufficient hosts, and vice versa. Joseph Sun discusses these papers in the context of other recent findings in a Minireview. Watercolor image represents the altered responsive states of NK cells. Artwork by Emilie Clark (firstname.lastname@example.org).
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Brief Definitive Report
NKX3.1 is a direct TAL1 target gene that mediates proliferation of TAL1-expressing human T cell acute lymphoblastic leukemia