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Volume 206, Issue 7

6 July 2009

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Cover Image

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ON THE COVER
B cells (green) capture antigens (red) from follicular dendritic cells in a mouse lymph node. Related article by Suzuki et al.
See page 1485
Table of Contents
Editorial Board

ISSN 0022-1007

EISSN 1540-9538

In this Issue

In This Issue
People & Ideas
Brief Definitive Report
Article
Correction

In This Issue

Pesticide-induced proliferation

Amy Maxmen

View Articletitled, Pesticide-induced proliferation

Spying on antigen hand-offs

Amy Maxmen

View Articletitled, Spying on antigen hand-offs

IL-17's tumor team

Amy Maxmen

View Articletitled, IL-17's tumor team

Healthy hearts lay off LOX

Amy Maxmen

View Articletitled, Healthy hearts lay off LOX

Mend that gut, STAT!

Amy Maxmen

View Articletitled, Mend that gut, STAT!

People & Ideas

HIV, prayer, and vintage cars: Danny Douek talks shop

Amy Maxmen

If a scientist is defined as a person who acquires knowledge methodologically, Douek fits the bill in every way.

View Articletitled, HIV, prayer, and vintage cars: Danny Douek talks shop

Brief Definitive Report

IL-17 can promote tumor growth through an IL-6–Stat3 signaling pathway

Lin Wang,Tangsheng Yi,Marcin Kortylewski,Drew M. Pardoll,Defu Zeng,Hua Yu

View Articletitled, IL-17 can promote tumor growth through an IL-6–Stat3 signaling pathway

STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing

Geethanjali Pickert,Clemens Neufert,Moritz Leppkes,Yan Zheng,Nadine Wittkopf,Moritz Warntjen,Hans-Anton Lehr,Sebastian Hirth,Benno Weigmann,Stefan Wirtz,Wenjun Ouyang,Markus F. Neurath,Christoph Becker

View Articletitled, STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing

Agricultural pesticide exposure and the molecular connection to lymphomagenesis

Julie Agopian,Jean-Marc Navarro,Anne-Claire Gac,Yannick Lecluse,Mélanie Briand,Pierre Grenot,Pascal Gauduchon,Philippe Ruminy,Pierre Lebailly,Bertrand Nadel,Sandrine Roulland

View Articletitled, Agricultural pesticide exposure and the molecular connection to lymphomagenesis

Visualizing B cell capture of cognate antigen from follicular dendritic cells

Kazuhiro Suzuki,Irina Grigorova,Tri Giang Phan,Lisa M. Kelly,Jason G. Cyster

View Articletitled, Visualizing B cell capture of cognate antigen from follicular dendritic cells

The B7 family member B7-H6 is a tumor cell ligand for the activating natural killer cell receptor NKp30 in humans

Cameron S. Brandt,Myriam Baratin,Eugene C. Yi,Jacob Kennedy,Zeren Gao,Brian Fox,Betty Haldeman,Craig D. Ostrander,Tomonori Kaifu,Christian Chabannon,Alessandro Moretta,Robert West,WenFeng Xu,Eric Vivier,Steven D. Levin

View Articletitled, The B7 family member B7-H6 is a tumor cell ligand for the activating natural killer cell receptor NKp30 in humans

The thymic medulla: a unique microenvironment for intercellular self-antigen transfer

Christian Koble,Bruno Kyewski

View Articletitled, The thymic medulla: a unique microenvironment for intercellular self-antigen transfer

Cytokine-dependent regulation of NADPH oxidase activity and the consequences for activated T cell homeostasis

Divya Purushothaman,Apurva Sarin

View Articletitled, Cytokine-dependent regulation of NADPH oxidase activity and the consequences for activated T cell homeostasis

Human naive and memory CD4⁺ T cell repertoires specific for naturally processed antigens analyzed using libraries of amplified T cells

Rebekka Geiger,Thomas Duhen,Antonio Lanzavecchia,Federica Sallusto

View Articletitled, Human naive and memory CD4+ T cell repertoires specific for naturally processed antigens analyzed using libraries of amplified T cells

Article

Peptide immunotherapy in allergic asthma generates IL-10–dependent immunological tolerance associated with linked epitope suppression

John D. Campbell,Karen F. Buckland,Sarah J. McMillan,Jennifer Kearley,William L.G. Oldfield,Lawrence J. Stern,Hans Grönlund,Marianne van Hage,Catherine J. Reynolds,Rosemary J. Boyton,Stephen P. Cobbold,A. Barry Kay,Daniel M. Altmann,Clare M. Lloyd,Mark Larché

View Articletitled, Peptide immunotherapy in allergic asthma generates IL-10–dependent immunological tolerance associated with linked epitope suppression

T-bet is essential for encephalitogenicity of both Th1 and Th17 cells

Yuhong Yang,Jeffrey Weiner,Yue Liu,Alan J. Smith,David J. Huss,Ryan Winger,Haiyan Peng,Petra D. Cravens,Michael K. Racke,Amy E. Lovett-Racke

View Articletitled, T-bet is essential for encephalitogenicity of both Th1 and Th17 cells

Cardiac 12/15 lipoxygenase–induced inflammation is involved in heart failure

Yosuke Kayama,Tohru Minamino,Haruhiro Toko,Masaya Sakamoto,Ippei Shimizu,Hidehisa Takahashi,Sho Okada,Kaoru Tateno,Junji Moriya,Masataka Yokoyama,Aika Nojima,Michihiro Yoshimura,Kensuke Egashira,Hiroyuki Aburatani,Issei Komuro

View Articletitled, Cardiac 12/15 lipoxygenase–induced inflammation is involved in heart failure

Profound CD4⁺/CCR5⁺ T cell expansion is induced by CD8⁺ lymphocyte depletion but does not account for accelerated SIV pathogenesis

Afam Okoye,Haesun Park,Mukta Rohankhedkar,Lia Coyne-Johnson,Richard Lum,Joshua M. Walker,Shannon L. Planer,Alfred W. Legasse,Andrew W. Sylwester,Michael Piatak, Jr.,Jeffrey D. Lifson,Donald L. Sodora,Francois Villinger,Michael K. Axthelm,Joern E. Schmitz,Louis J. Picker

View Articletitled, Profound CD4+/CCR5+ T cell expansion is induced by CD8+ lymphocyte depletion but does not account for accelerated SIV pathogenesis

Dendritic cells require a systemic type I interferon response to mature and induce CD4⁺ Th1 immunity with poly IC as adjuvant

M. Paula Longhi,Christine Trumpfheller,Juliana Idoyaga,Marina Caskey,Ines Matos,Courtney Kluger,Andres M. Salazar,Marco Colonna,Ralph M. Steinman

View Articletitled, Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant

Regulation of TLR7/9 responses in plasmacytoid dendritic cells by BST2 and ILT7 receptor interaction

Wei Cao,Laura Bover,Minkwon Cho,Xiaoxia Wen,Shino Hanabuchi,Musheng Bao,David B. Rosen,Yi-Hong Wang,Joanne L. Shaw,Qiumei Du,Chun Li,Naoko Arai,Zhengbin Yao,Lewis L. Lanier,Yong-Jun Liu

View Articletitled, Regulation of TLR7/9 responses in plasmacytoid dendritic cells by BST2 and ILT7 receptor interaction

A mutation in Irak2c identifies IRAK-2 as a central component of the TLR regulatory network of wild-derived mice

James R. Conner,Irina I. Smirnova,Alexander Poltorak

View Articletitled, A mutation in Irak2c identifies IRAK-2 as a central component of the TLR regulatory network of wild-derived mice

Correction

CSL–MAML-dependent Notch1 signaling controls T lineage–specific IL-7Rα gene expression in early human thymopoiesis and leukemia

Sara González-García,Marina García-Peydró,Enrique Martín-Gayo,Esteban Ballestar,Manel Esteller,Rafael Bornstein,José Luis de la Pompa,Adolfo A. Ferrando,María L. Toribio

View Articletitled, CSL–MAML-dependent Notch1 signaling controls T lineage–specific IL-7Rα gene expression in early human thymopoiesis and leukemia

Cholera toxin inhibits IL-12 production and CD8α⁺ dendritic cell differentiation by cAMP-mediated inhibition of IRF8 function

Andrea la Sala,Jianping He,Leopoldo Laricchia-Robbio,Stefania Gorini,Akiko Iwasaki,Michael Braun,George S. Yap,Alan Sher,Keiko Ozato,Brian Kelsall

View Articletitled, Cholera toxin inhibits IL-12 production and CD8α+ dendritic cell differentiation by cAMP-mediated inhibition of IRF8 function

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