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28 September 2009
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Cover Image
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ON THE COVER
Colored SEM of pathogenic E. coli (green) embedded in the small intestine. Mice expressing a human glycoprotein highly expressed in Crohn's disease developed severe gut inflammation when fed pathogenic E. coli. Related article by Carvalho et al.
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ISSN 0022-1007
EISSN 1540-9538
In This Issue
People & Ideas
Mickie Bhatia: Embryonic stem cells come of age
Mickie Bhatia wants to tap into the therapeutic potential of human stem cells, and he's finding ways to overcome the obstacles that stand in his way.
Meeting Review
Brief Definitive Report
Loss of SOCS3 expression in T cells reveals a regulatory role for interleukin-17 in atherosclerosis
Soraya Taleb,Mélissa Romain,Bhama Ramkhelawon,Catherine Uyttenhove,Gerard Pasterkamp,Olivier Herbin,Bruno Esposito,Nicolas Perez,Hideo Yasukawa,Jacques Van Snick,Akihiko Yoshimura,Alain Tedgui,Ziad Mallat
The nuclear receptor PPARγ selectively inhibits Th17 differentiation in a T cell–intrinsic fashion and suppresses CNS autoimmunity
Luisa Klotz,Sven Burgdorf,Indra Dani,Kaoru Saijo,Juliane Flossdorf,Stephanie Hucke,Judith Alferink,Natalija Novak,Marc Beyer,Gunter Mayer,Birgit Langhans,Thomas Klockgether,Ari Waisman,Gerard Eberl,Joachim Schultze,Michael Famulok,Waldemar Kolanus,Christopher Glass,Christian Kurts,Percy A. Knolle
Article
Pathogenicity of a disease-associated human IL-4 receptor allele in experimental asthma
Raffi Tachdjian,Clinton Mathias,Shadi Al Khatib,Paul J. Bryce,Hong S. Kim,Frank Blaeser,Brian D. O'Connor,Danuta Rzymkiewicz,Andrew Chen,Michael J. Holtzman,Gurjit K. Hershey,Holger Garn,Hani Harb,Harald Renz,Hans C. Oettgen,Talal A. Chatila
A murine DC-SIGN homologue contributes to early host defense against Mycobacterium tuberculosis
Antoine Tanne,Bo Ma,Frédéric Boudou,Ludovic Tailleux,Hélène Botella,Edgar Badell,Florence Levillain,Maureen E. Taylor,Kurt Drickamer,Jérome Nigou,Karen M. Dobos,Germain Puzo,Dietmar Vestweber,Martin K. Wild,Marie Marcinko,Peter Sobieszczuk,Lauren Stewart,Daniel Lebus,Brigitte Gicquel,Olivier Neyrolles
Correction
Blood leukocyte microarrays to diagnose systemic onset juvenile idiopathic arthritis and follow the response to IL-1 blockade
Florence Allantaz,Damien Chaussabel,Dorothee Stichweh,Lynda Bennett,Windy Allman,Asuncion Mejias,Monica Ardura,Wendy Chung,Elisabeth Smith,Carol Wise,Karolina Palucka,Octavio Ramilo,Marilynn Punaro,Jacques Banchereau,Virginia Pascual
Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease
Andrew M. Smith,Farooq Z. Rahman,Bu'Hussain Hayee,Simon J. Graham,Daniel J.B. Marks,Gavin W. Sewell,Christine D. Palmer,Jonathan Wilde,Brian M.J. Foxwell,Israel S. Gloger,Trevor Sweeting,Mark Marsh,Ann P. Walker,Stuart L. Bloom,Anthony W. Segal
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