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Editorial

Irreproducible results: a response to Thomson Scientific

Mike Rossner,Heather Van Epps,Emma Hill
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In This Issue

Unmasking an inflammatory suppressor

Hema Bashyam
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Toll signals provoke plaque buildup

Hema Bashyam
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Long-lasting Toll suppression

Hema Bashyam
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Averting danger from within

Hema Bashyam
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VEGF blockade damages brain vessels

Hema Bashyam
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People & Ideas

Anthony De Tomaso: Finding the origins of adaptive immunity

Hema Bashyam
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Commentary

Inciting inflammation: the RAGE about tumor promotion

Michael Dougan,Glenn Dranoff
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An antidote for Staphylococcus aureus pneumonia?

Frank R. DeLeo,Michael Otto
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Brief Definitive Report

RAGE signaling sustains inflammation and promotes tumor development

Christoffer Gebhardt,Astrid Riehl,Moritz Durchdewald,Julia Németh,Gerhard Fürstenberger,Karin Müller-Decker,Alexander Enk,Bernd Arnold,Angelika Bierhaus,Peter P. Nawroth,Jochen Hess,Peter Angel
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Vaccine protection against Staphylococcus aureus pneumonia

Juliane Bubeck Wardenburg,Olaf Schneewind
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Periostin is essential for cardiac healingafter acute myocardial infarction

Masashi Shimazaki,Kazuto Nakamura,Isao Kii,Takeshi Kashima,Norio Amizuka,Minqi Li,Mitsuru Saito,Keiichi Fukuda,Takashi Nishiyama,Satoshi Kitajima,Yumiko Saga,Masashi Fukayama,Masataka Sata,Akira Kudo
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Forward genetic analysis of Toll-like receptor responses in wild-derived mice reveals a novel antiinflammatory role for IRAK1BP1

James R. Conner,Irina I. Smirnova,Alexander Poltorak
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PI3K is critical for the nuclear translocation of IRF-7 and type I IFN production by human plasmacytoid predendritic cells in response to TLR activation

Cristiana Guiducci,Cristina Ghirelli,Marie-Annick Marloie-Provost,Tracy Matray,Robert L. Coffman,Yong-Jun Liu,Franck J. Barrat,Vassili Soumelis
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Sustained desensitization to bacterial Toll-like receptor ligands after resolutionof respiratory influenza infection

Arnaud Didierlaurent,John Goulding,Seema Patel,Robert Snelgrove,Lionel Low,Magali Bebien,Toby Lawrence,Leonie S. van Rijt,Bart N. Lambrecht,Jean-Claude Sirard,Tracy Hussell
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Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases

Maria Armaka,Maria Apostolaki,Peggy Jacques,Dimitris L. Kontoyiannis,Dirk Elewaut,George Kollias
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IL-33 reduces the development of atherosclerosis

Ashley M. Miller,Damo Xu,Darren L. Asquith,Laura Denby,Yubin Li,Naveed Sattar,Andrew H. Baker,Iain B. McInnes,Foo Y. Liew
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Article

iPLA2β: front and center in human monocyte chemotaxis to MCP-1

Ravi S. Mishra,Kevin A. Carnevale,Martha K. Cathcart
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Pulmonary arterial remodeling induced by a Th2 immune response

Eleen Daley,Claire Emson,Christophe Guignabert,Rene de Waal Malefyt,Jennifer Louten,Viswanath P. Kurup,Cory Hogaboam,Laimute Taraseviciene-Stewart,Norbert F. Voelkel,Marlene Rabinovitch,Ekkehard Grunig,Gabriele Grunig
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Increased endothelial expression of Toll-like receptor 2 at sites of disturbed blood flow exacerbates early atherogenic events

Adam E. Mullick,Katrin Soldau,William B. Kiosses,Thomas A. Bell, III,Peter S. Tobias,Linda K. Curtiss
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Ozone exposure in a mouse model induces airway hyperreactivity that requires the presence of natural killer T cells and IL-17

Muriel Pichavant,Sho Goya,Everett H. Meyer,Richard A. Johnston,Hye Y. Kim,Ponpan Matangkasombut,Ming Zhu,Yoichiro Iwakura,Paul B. Savage,Rosemarie H. DeKruyff,Stephanie A. Shore,Dale T. Umetsu
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Inhibition of histamine-mediated signaling confers significant protection against severe malaria in mouse models of disease

Walid Beghdadi,Adeline Porcherie,Bradley S. Schneider,David Dubayle,Roger Peronet,Michel Huerre,Takeshi Watanabe,Hiroshi Ohtsu,Jacques Louis,Salaheddine Mécheri
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Oct2 enhances antibody-secreting cell differentiation through regulation of IL-5 receptor α chain expression on activated B cells

Dianne Emslie,Kathy D'Costa,Jhagvaral Hasbold,Donald Metcalf,Kiyoshi Takatsu,Philip O. Hodgkin,Lynn M. Corcoran
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Altered development of the brain after focal herpesvirus infection of the central nervous system

Thad Koontz,Marina Bralic,Jelena Tomac,Ester Pernjak-Pugel,Glen Bantug,Stipan Jonjic,William J. Britt
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Microbe sampling by mucosal dendritic cells is a discrete, MyD88-independent stepin ΔinvG S. Typhimurium colitis

Siegfried Hapfelmeier,Andreas J. Müller,Bärbel Stecher,Patrick Kaiser,Manja Barthel,Kathrin Endt,Matthias Eberhard,Riccardo Robbiani,Christoph A. Jacobi,Mathias Heikenwalder,Carsten Kirschning,Steffen Jung,Thomas Stallmach,Marcus Kremer,Wolf-Dietrich Hardt
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Homeostatic MyD88-dependent signals cause lethal inflamMation in the absence of A20

Emre E. Turer,Rita M. Tavares,Erwan Mortier,Osamu Hitotsumatsu,Rommel Advincula,Bettina Lee,Nataliya Shifrin,Barbara A. Malynn,Averil Ma
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Targeted inactivation of the COP9 signalosome impairs multiple stagesof T cell development

Martina Panattoni,Francesca Sanvito,Veronica Basso,Claudio Doglioni,Giulia Casorati,Eugenio Montini,Jeffrey R. Bender,Anna Mondino,Ruggero Pardi
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Essential but differential role for CXCR4 and CXCR7 in the therapeutic homingof human renal progenitor cells

Benedetta Mazzinghi,Elisa Ronconi,Elena Lazzeri,Costanza Sagrinati,Lara Ballerini,Maria Lucia Angelotti,Eliana Parente,Rosa Mancina,Giuseppe Stefano Netti,Francesca Becherucci,Mauro Gacci,Marco Carini,Loreto Gesualdo,Mario Rotondi,Enrico Maggi,Laura Lasagni,Mario Serio,Sergio Romagnani,Paola Romagnani
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VEGF and TGF-β are required for the maintenance of the choroid plexus and ependyma

Arindel S.R. Maharaj,Tony E. Walshe,Magali Saint-Geniez,Shivalingappa Venkatesha,Angel E. Maldonado,Nathan C. Himes,Kabir S. Matharu,S. Ananth Karumanchi,Patricia A. D'Amore
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