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24 November 2008
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ON THE COVER
Image provided by Scott Camazine/Photo Researchers, Inc. Meiler et al. show how beekeepers tolerate hundreds of stings. After multiple jabs, T cells specific for bee toxins switch from producing inflammatory cytokines to producing suppressive cytokines, thus stifling excessive inflammation.
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ISSN 0022-1007
EISSN 1540-9538
In this Issue
In This Issue
People & Ideas
Commentary
Brief Definitive Report
Familial pulmonary alveolar proteinosis caused by mutations in CSF2RA
Takuji Suzuki,Takuro Sakagami,Bruce K. Rubin,Lawrence M. Nogee,Robert E. Wood,Sarah L. Zimmerman,Teresa Smolarek,Megan K. Dishop,Susan E. Wert,Jeffrey A. Whitsett,Gregory Grabowski,Brenna C. Carey,Carrie Stevens,Johannes C.M. van der Loo,Bruce C. Trapnell
Pulmonary alveolar proteinosis caused by deletion of the GM-CSFRα gene in the X chromosome pseudoautosomal region 1
Margarita Martinez-Moczygemba,Minh L. Doan,Okan Elidemir,Leland L. Fan,Sau Wai Cheung,Jonathan T. Lei,James P. Moore,Ghamartaj Tavana,Lora R. Lewis,Yiming Zhu,Donna M. Muzny,Richard A. Gibbs,David P. Huston
Article
Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection
R. Brad Jones,Lishomwa C. Ndhlovu,Jason D. Barbour,Prameet M. Sheth,Aashish R. Jha,Brian R. Long,Jessica C. Wong,Malathy Satkunarajah,Marc Schweneker,Joan M. Chapman,Gabor Gyenes,Bahareh Vali,Martin D. Hyrcza,Feng Yun Yue,Colin Kovacs,Aref Sassi,Mona Loutfy,Roberta Halpenny,Desmond Persad,Gerald Spotts,Frederick M. Hecht,Tae-Wook Chun,Joseph M. McCune,Rupert Kaul,James M. Rini,Douglas F. Nixon,Mario A. Ostrowski
Valproic acid inhibits Aβ production, neuritic plaque formation, and behavioral deficits in Alzheimer's disease mouse models
Hong Qing,Guiqiong He,Philip T. T. Ly,Christopher J. Fox,Matthias Staufenbiel,Fang Cai,Zhuohua Zhang,Shengcai Wei,Xiulian Sun,Chia-Hsiung Chen,Weihui Zhou,Ke Wang,Weihong Song
Tpl2 kinase regulates T cell interferon-γ production and host resistance to Toxoplasma gondii
Wendy T. Watford,Bruce D. Hissong,Lydia R. Durant,Hidehiro Yamane,Linda M. Muul,Yuka Kanno,Cristina M. Tato,Haydeé L. Ramos,Alan E. Berger,Lisa Mielke,Marko Pesu,Benjamin Solomon,David M. Frucht,William E. Paul,Alan Sher,Dragana Jankovic,Philip N. Tsichlis,John J. O'Shea
Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance
Masashi Yano,Noriyuki Kuroda,Hongwei Han,Makiko Meguro-Horike,Yumiko Nishikawa,Hiroshi Kiyonari,Kentaro Maemura,Yuchio Yanagawa,Kunihiko Obata,Satoru Takahashi,Tomokatsu Ikawa,Rumi Satoh,Hiroshi Kawamoto,Yasuhiro Mouri,Mitsuru Matsumoto
Toward targeting B cell cancers with CD4+ CTLs: identification of a CD19-encoded minor histocompatibility antigen using a novel genome-wide analysis
Robbert M. Spaapen,Henk M. Lokhorst,Kelly van den Oudenalder,Brith E. Otterud,Harry Dolstra,Mark F. Leppert,Monique C. Minnema,Andries C. Bloem,Tuna Mutis
A point mutation in the murine Hem1 gene reveals an essential role for Hematopoietic Protein 1 in lymphopoiesis and innate immunity
Heon Park,Karen Staehling-Hampton,Mark W. Appleby,Mary E. Brunkow,Tania Habib,Yi Zhang,Fred Ramsdell,H. Denny Liggitt,Brian Freie,Mark Tsang,George Carlson,Sherree Friend,Charles Frevert,Brian M. Iritani
VE-PTP maintains the endothelial barrier via plakoglobin and becomes dissociated from VE-cadherin by leukocytes and by VEGF
Astrid F. Nottebaum,Giuseppe Cagna,Mark Winderlich,Alexander C. Gamp,Ruth Linnepe,Christian Polaschegg,Kristina Filippova,Ruth Lyck,Britta Engelhardt,Olena Kamenyeva,Maria Gabriele Bixel,Stefan Butz,Dietmar Vestweber
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