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Volume 205, Issue 1
21 January 2008
Journal of Experimental Medicine Cover Image for Volume 205, Issue 1
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  • Cover Image

    Cover Image

    issue cover

    ON THE COVER
    Artwork (cut Coloroid paper on paper) by New York artist Rachel Urkowitz ([email protected]). Antibodies induced by vaccines (red) based on conserved bacterial antigens (yellow) cause the destruction of all pneumococcal variants (brown), whereas antibodies induced by nonconserved antigens (green) allow many variants to escape. Related article by Giefing et al.
    See page 117

  • PDF Icon PDF LinkTable of Contents
  • PDF Icon PDF LinkEditorial Board
ISSN 0022-1007
EISSN 1540-9538

In This Issue

Scar-free healing
Hema Bashyam
View Articletitled, Scar-free healing
Helping lymphocytes to move on
Hema Bashyam
View Articletitled, Helping lymphocytes to move on
Block the zinc, starve the virus
Hema Bashyam
View Articletitled, Block the zinc, starve the virus
New vaccines may provide full coverage
Hema Bashyam
View Articletitled, New vaccines may provide full coverage
An inflammation-enhancing virus
Hema Bashyam
View Articletitled, An inflammation-enhancing virus

People & Ideas

Alan Aderem: From molecules to megabytes
Nicole LeBrasseur
View Articletitled, Alan Aderem: From molecules to megabytes

Commentary

The failed HIV Merck vaccine study: a step back or a launching point for future vaccine development?
Rafick-Pierre Sekaly
View Articletitled, The failed HIV Merck vaccine study: a step back or a launching point for future vaccine development?
Alarming dendritic cells for Th2 induction
Andrew S. MacDonald,Rick M. Maizels
View Articletitled, Alarming dendritic cells for Th2 induction

Brief Definitive Report

Human CMV infection induces 5-lipoxygenase expression and leukotriene B4 production in vascular smooth muscle cells
Hong Qiu,Klas Strååt,Afsar Rahbar,Min Wan,Cecilia Söderberg-Nauclér,Jesper Z. Haeggström
View Articletitled, Human CMV infection induces 5-lipoxygenase expression and leukotriene B<sub>4</sub> production in vascular smooth muscle cells
Syndecan-4 protects against osteopontin-mediated acute hepatic injury by masking functional domains of osteopontin
Shigeyuki Kon,Masahiro Ikesue,Chiemi Kimura,Momoe Aoki,Yosuke Nakayama,Yoshinari Saito,Daisuke Kurotaki,Hongyan Diao,Yutaka Matsui,Tatsuya Segawa,Masahiro Maeda,Tetsuhito Kojima,Toshimitsu Uede
View Articletitled, Syndecan-4 protects against osteopontin-mediated acute hepatic injury by masking functional domains of osteopontin
Regulation of cellular zinc balance as a potential mechanism of EVER-mediated protection against pathogenesis by cutaneous oncogenic human papillomaviruses
Maciej Lazarczyk,Christian Pons,José-Andrès Mendoza,Patricia Cassonnet,Yves Jacob,Michel Favre
View Articletitled, Regulation of cellular zinc balance as a potential mechanism of EVER-mediated protection against pathogenesis by cutaneous oncogenic human papillomaviruses
Molecular mechanisms linking wound inflammation and fibrosis: knockdown of osteopontin leads to rapid repair and reduced scarring
Ryoichi Mori,Tanya J. Shaw,Paul Martin
View Articletitled, Molecular mechanisms linking wound inflammation and fibrosis: knockdown of osteopontin leads to rapid repair and reduced scarring
Long-lived virus-reactive memory T cells generated from purified cytokine-secreting T helper type 1 and type 2 effectors
Max Löhning,Ahmed N. Hegazy,Daniel D. Pinschewer,Dorothea Busse,Karl S. Lang,Thomas Höfer,Andreas Radbruch,Rolf M. Zinkernagel,Hans Hengartner
View Articletitled, Long-lived virus-reactive memory T cells generated from purified cytokine-secreting T helper type 1 and type 2 effectors

Article

An HIV-1 clade C DNA prime, NYVAC boost vaccine regimen induces reliable, polyfunctional, and long-lasting T cell responses
Alexandre Harari,Pierre-Alexandre Bart,Wolfgang Stöhr,Gonzalo Tapia,Miguel Garcia,Emmanuelle Medjitna-Rais,Séverine Burnet,Cristina Cellerai,Otto Erlwein,Tristan Barber,Christiane Moog,Peter Liljestrom,Ralf Wagner,Hans Wolf,Jean-Pierre Kraehenbuhl,Mariano Esteban,Jonathan Heeney,Marie-Joelle Frachette,James Tartaglia,Sheena McCormack,Abdel Babiker,Jonathan Weber,Giuseppe Pantaleo
View Articletitled, An HIV-1 clade C DNA prime, NYVAC boost vaccine regimen induces reliable, polyfunctional, and long-lasting T cell responses
Eosinophil-derived neurotoxin acts as an alarmin to activate the TLR2–MyD88 signal pathway in dendritic cells and enhances Th2 immune responses
De Yang,Qian Chen,Shao Bo Su,Ping Zhang,Kahori Kurosaka,Rachel R. Caspi,Suzanne M. Michalek,Helene F. Rosenberg,Ning Zhang,Joost J. Oppenheim
View Articletitled, Eosinophil-derived neurotoxin acts as an alarmin to activate the TLR2–MyD88 signal pathway in dendritic cells and enhances Th2 immune responses
Regulation of liver regeneration and hepatocarcinogenesis by suppressor of cytokine signaling 3
Kimberly J. Riehle,Jean S. Campbell,Ryan S. McMahan,Melissa M. Johnson,Richard P. Beyer,Theo K. Bammler,Nelson Fausto
View Articletitled, Regulation of liver regeneration and hepatocarcinogenesis by suppressor of cytokine signaling 3
Initiation of the adaptive immune response to Mycobacterium tuberculosis depends on antigen production in the local lymph node, not the lungs
Andrea J. Wolf,Ludovic Desvignes,Beth Linas,Niaz Banaiee,Toshiki Tamura,Kiyoshi Takatsu,Joel D. Ernst
View Articletitled, Initiation of the adaptive immune response to <em>Mycobacterium tuberculosis</em> depends on antigen production in the local lymph node, not the lungs
Discovery of a novel class of highly conserved vaccine antigens using genomic scale antigenic fingerprinting of pneumococcus with human antibodies
Carmen Giefing,Andreas L. Meinke,Markus Hanner,Tamás Henics,Duc Bui Minh,Dieter Gelbmann,Urban Lundberg,Beatrice M. Senn,Michael Schunn,Andre Habel,Birgitta Henriques-Normark,Åke Örtqvist,Mats Kalin,Alexander von Gabain,Eszter Nagy
View Articletitled, Discovery of a novel class of highly conserved vaccine antigens using genomic scale antigenic fingerprinting of pneumococcus with human antibodies
Borrelia burgdorferi basic membrane proteins A and B participate in the genesis of Lyme arthritis
Utpal Pal,Penghua Wang,Fukai Bao,Xiuli Yang,Swapna Samanta,Robert Schoen,Gary P. Wormser,Ira Schwartz,Erol Fikrig
View Articletitled, <em>Borrelia burgdorferi</em> basic membrane proteins A and B participate in the genesis of Lyme arthritis
Secretory IgA mediates retrotranscytosis of intact gliadin peptides via the transferrin receptor in celiac disease
Tamara Matysiak-Budnik,Ivan Cruz Moura,Michelle Arcos-Fajardo,Corinne Lebreton,Sandrine Ménard,Céline Candalh,Karima Ben-Khalifa,Christophe Dugave,Houda Tamouza,Guillaume van Niel,Yoram Bouhnik,Dominique Lamarque,Stanislas Chaussade,Georgia Malamut,Christophe Cellier,Nadine Cerf-Bensussan,Renato C. Monteiro,Martine Heyman
View Articletitled, Secretory IgA mediates retrotranscytosis of intact gliadin peptides via the transferrin receptor in celiac disease
Characterization of a late transitional B cell population highly sensitive to BAFF-mediated homeostatic proliferation
Almut Meyer-Bahlburg,Sarah F. Andrews,Karl O.A. Yu,Steven A. Porcelli,David J. Rawlings
View Articletitled, Characterization of a late transitional B cell population highly sensitive to BAFF-mediated homeostatic proliferation
Mannose-binding lectin enhances Toll-like receptors 2 and 6 signaling from the phagosome
W.K. Eddie Ip,Kazue Takahashi,Kathryn J. Moore,Lynda M. Stuart,R. Alan B. Ezekowitz
View Articletitled, Mannose-binding lectin enhances Toll-like receptors 2 and 6 signaling from the phagosome
Developmental switch of intestinal antimicrobial peptide expression
Sandrine Ménard,Valentina Förster,Michael Lotz,Dominique Gütle,Claudia U. Duerr,Richard L. Gallo,Birgitta Henriques-Normark,Katrin Pütsep,Mats Andersson,Erik O. Glocker,Mathias W. Hornef
View Articletitled, Developmental switch of intestinal antimicrobial peptide expression
Nonmuscle myosin heavy chain IIA mediates integrin LFA-1 de-adhesion during T lymphocyte migration
Nicole A. Morin,Patrick W. Oakes,Young-Min Hyun,Dooyoung Lee,Y. Eugene Chin,Michael R. King,Timothy A. Springer,Motomu Shimaoka,Jay X. Tang,Jonathan S. Reichner,Minsoo Kim
View Articletitled, Nonmuscle myosin heavy chain IIA mediates integrin LFA-1 de-adhesion during T lymphocyte migration
Innocuous IFNγ induced by adjuvant-free antigen restores normoglycemia in NOD mice through inhibition of IL-17 production
Renu Jain,Danielle M. Tartar,Randal K. Gregg,Rohit D. Divekar,J. Jeremiah Bell,Hyun-Hee Lee,Ping Yu,Jason S. Ellis,Christine M. Hoeman,Craig L. Franklin,Habib Zaghouani
View Articletitled, Innocuous IFNγ induced by adjuvant-free antigen restores normoglycemia in NOD mice through inhibition of IL-17 production
MerTK is required for apoptotic cell–induced T cell tolerance
Mark A. Wallet,Pradip Sen,Rafael R. Flores,Yaming Wang,Zuoan Yi,Yingsu Huang,Clayton E. Mathews,H. Shelton Earp,Glenn Matsushima,Bo Wang,Roland Tisch
View Articletitled, MerTK is required for apoptotic cell–induced T cell tolerance
TLR-dependent cross talk between human Kupffer cells and NK cells
Zhengkun Tu,Adel Bozorgzadeh,Robert H. Pierce,Jonathan Kurtis,I. Nicholas Crispe,Mark S. Orloff
View Articletitled, TLR-dependent cross talk between human Kupffer cells and NK cells
Development of all CD4 T lineages requires nuclear factor TOX
Parinaz Aliahmad,Jonathan Kaye
View Articletitled, Development of all CD4 T lineages requires nuclear factor TOX

Correction

Skin DCs go deeper
Richard Robinson
View Articletitled, Skin DCs go deeper

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