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    In T cell acute lymphoblastic leukemia, FBW7 missense mutations block the addition of ubiquitins and proteosomal targeting of intranuclear NOTCH, thus increasing Myc activation. See related articles by O'Neil et al. and Thompson et al.
    See pages 1813 and 1825

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ISSN 0022-1007
EISSN 1540-9538

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