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11 June 2007
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Medullary thymic epithelial cells (blue) expressing the transcription factor Aire (red) eliminate self-reactive T cells. Expression of Aire requires RANK-RANKL signals. Related article by Rossi et al.
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ISSN 0022-1007
EISSN 1540-9538
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In This Issue
From the Archive
Commentary
Brief Definitive Report
Spontaneous hemolytic uremic syndrome triggered by complement factor H lacking surface recognition domains
Matthew C. Pickering,Elena Goicoechea de Jorge,Rubén Martinez-Barricarte,Sergio Recalde,Alfredo Garcia-Layana,Kirsten L. Rose,Jill Moss,Mark J. Walport,H. Terence Cook,Santiago Rodriguez de Córdoba,Marina Botto
RANK signals from CD4+3− inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla
Simona W. Rossi,Mi-Yeon Kim,Andreas Leibbrandt,Sonia M. Parnell,William E. Jenkinson,Stephanie H. Glanville,Fiona M. McConnell,Hamish S. Scott,Josef M. Penninger,Eric J. Jenkinson,Peter J.L. Lane,Graham Anderson
Cyclic adenosine monophosphate is a key component of regulatory T cell–mediated suppression
Tobias Bopp,Christian Becker,Matthias Klein,Stefan Klein-Heßling,Alois Palmetshofer,Edgar Serfling,Valeska Heib,Marc Becker,Jan Kubach,Steffen Schmitt,Sabine Stoll,Hansjörg Schild,Martin S. Staege,Michael Stassen,Helmut Jonuleit,Edgar Schmitt
A novel inhibitor of the alternative pathway of complement reverses inflammation and bone destruction in experimental arthritis
Kenneth J. Katschke, Jr.,Karim Y. Helmy,Micah Steffek,Hongkang Xi,JianPing Yin,Wyne P. Lee,Peter Gribling,Kai H. Barck,Richard A.D. Carano,Robin E. Taylor,Linda Rangell,Lauri Diehl,Philip E. Hass,Christian Wiesmann,Menno van Lookeren Campagne
Article
Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8+ T cell responses
Melissa L. Precopio,Michael R. Betts,Janie Parrino,David A. Price,Emma Gostick,David R. Ambrozak,Tedi E. Asher,Daniel C. Douek,Alexandre Harari,Giuseppe Pantaleo,Robert Bailer,Barney S. Graham,Mario Roederer,Richard A. Koup
MyD88-dependent expansion of an immature GR-1+CD11b+ population induces T cell suppression and Th2 polarization in sepsis
Matthew J. Delano,Philip O. Scumpia,Jason S. Weinstein,Dominique Coco,Srinivas Nagaraj,Kindra M. Kelly-Scumpia,Kerri A. O'Malley,James L. Wynn,Svetlana Antonenko,Samer Z. Al-Quran,Ryan Swan,Chun-Shiang Chung,Mark A. Atkinson,Reuben Ramphal,Dmitry I. Gabrilovich,Wesley H. Reeves,Alfred Ayala,Joseph Phillips,Drake LaFace,Paul G. Heyworth,Michael Clare-Salzler,Lyle L. Moldawer
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