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Editorial

JEM content to be deposited automatically in PubMed Central

Mike Rossner
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In This Issue

Surviving malaria, dying of typhoid

Hema Bashyam
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Notch signals spread breast cancer

Hema Bashyam
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Rehydrating hormone smothers inflammation

Hema Bashyam
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Improved mucosal vaccines

Hema Bashyam
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Monocyte diversity heals hearts

Hema Bashyam
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From the Archive

Lewis Thomas and droopy rabbit ears

Hema Bashyam
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Article

Yellow fever and Max Theiler: the only Nobel Prize for a virus vaccine

Erling Norrby
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A viral CTL escape mutation leading to immunoglobulin-like transcript 4–mediated functional inhibition of myelomonocytic cells

Mathias Lichterfeld,Daniel G. Kavanagh,Katie L. Williams,Beenu Moza,Stanley K. Mui,ToshiYuki Miura,Rohini Sivamurthy,Rachel Allgaier,Florencia Pereyra,Alicja Trocha,Margaret Feeney,Rajesh T. Gandhi,Eric S. Rosenberg,Marcus Altfeld,Todd M. Allen,Rachel Allen,Bruce D. Walker,Eric J. Sundberg,Xu G. Yu
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Ets-1 is a negative regulator of Th17 differentiation

Jacques Moisan,Roland Grenningloh,Estelle Bettelli,Mohamed Oukka,I-Cheng Ho
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Hormonal control of the renal immune response and antibacterial host defense by arginine vasopressin

Cécilia Chassin,Mathias W. Hornef,Marcelle Bens,Michael Lotz,Jean-Michel Goujon,Sophie Vimont,Guillaume Arlet,Alexandre Hertig,Eric Rondeau,Alain Vandewalle
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Reduced receptor editing in lupus-prone MRL/lpr mice

Jennifer L. Lamoureux,Lisa C. Watson,Marie Cherrier,Patrick Skog,David Nemazee,Ann J. Feeney
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Facilitation of Th1-mediated immune response by prostaglandin E receptor EP1

Miyako Nagamachi,Daiji Sakata,Kenji Kabashima,Tomoyuki Furuyashiki,Takahiko Murata,Eri Segi-Nishida,Kitipong Soontrapa,Toshiyuki Matsuoka,Yoshiki Miyachi,Shuh Narumiya
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Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis

Ichiro Onoyama,Ryosuke Tsunematsu,Akinobu Matsumoto,Taichi Kimura,Ignacio Moreno de Alborán,Keiko Nakayama,Keiichi I. Nakayama
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An ITAM-signaling pathway controls cross-presentation of particulate but not soluble antigens in dendritic cells

Daniel B. Graham,Linda M. Stephenson,Siu Kit Lam,Karry Brim,Hyang Mi Lee,Jhoanne Bautista,Susan Gilfillan,Shreeram Akilesh,Keiko Fujikawa,Wojciech Swat
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Dysregulated Epstein-Barr virus infection in the multiple sclerosis brain

Barbara Serafini,Barbara Rosicarelli,Diego Franciotta,Roberta Magliozzi,Richard Reynolds,Paola Cinque,Laura Andreoni,Pankaj Trivedi,Marco Salvetti,Alberto Faggioni,Francesca Aloisi
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HMGB1 release induced by liver ischemia involves Toll-like receptor 4–dependent reactive oxygen species production and calcium-mediated signaling

Allan Tsung,John R. Klune,Xianghong Zhang,Geetha Jeyabalan,Zongxian Cao,Ximei Peng,Donna B. Stolz,David A. Geller,Matthew R. Rosengart,Timothy R. Billiar
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Notch ligand Delta-like 4 regulates disease pathogenesis during respiratory viral infections by modulating Th2 cytokines

Matthew A. Schaller,Rupak Neupane,Brian D. Rudd,Steven L. Kunkel,Lara E. Kallal,Pamela Lincoln,John B. Lowe,Yunfang Man,Nicholas W. Lukacs
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Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin

Kevin G. Leong,Kyle Niessen,Iva Kulic,Afshin Raouf,Connie Eaves,Ingrid Pollet,Aly Karsan
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Pyruvate kinase deficiency confers susceptibility to Salmonella typhimurium infection in mice

Marie-France Roy,Noémie Riendeau,Christian Bédard,Pierre Hélie,Gundula Min-Oo,Karine Turcotte,Philippe Gros,François Canonne-Hergaux,Danielle Malo
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A protein associated with Toll-like receptor (TLR) 4 (PRAT4A) is required for TLR-dependent immune responses

Koichiro Takahashi,Takuma Shibata,Sachiko Akashi-Takamura,Takashi Kiyokawa,Yasutaka Wakabayashi,Natsuko Tanimura,Toshihiko Kobayashi,Fumi Matsumoto,Ryutaro Fukui,Taku Kouro,Yoshinori Nagai,Kiyoshi Takatsu,Shin-ichiroh Saitoh,Kensuke Miyake
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Phosphoinositide 3–kinase γ participates in T cell receptor–induced T cell activation

Isabela Alcázar,Miriam Marqués,Amit Kumar,Emilio Hirsch,Matthias Wymann,Ana C. Carrera,Domingo F. Barber
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AID-deficient Bcl-xL transgenic mice develop delayed atypical plasma cell tumors with unusual Ig/Myc chromosomal rearrangements

Alexander L. Kovalchuk,Wendy duBois,Elizabeth Mushinski,Nicole E. McNeil,Carsten Hirt,Chen-Feng Qi,Zhaoyang Li,Siegfried Janz,Tasuku Honjo,Masamichi Muramatsu,Thomas Ried,Timothy Behrens,Michael Potter
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BCL11B is required for positive selection and survival of double-positive thymocytes

Diana I. Albu,Dongyun Feng,Debarati Bhattacharya,Nancy A. Jenkins,Neal G. Copeland,Pentao Liu,Dorina Avram
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APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination

Jeroen E.J. Guikema,Erin K. Linehan,Daisuke Tsuchimoto,Yusaku Nakabeppu,Phyllis R. Strauss,Janet Stavnezer,Carol E. Schrader
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Differential natural killer cell–mediated inhibition of HIV-1 replication based on distinct KIR/HLA subtypes

Galit Alter,Maureen P. Martin,Nickolas Teigen,William H. Carr,Todd J. Suscovich,Arne Schneidewind,Hendrik Streeck,Michael Waring,Angela Meier,Christian Brander,Jeffrey D. Lifson,Todd M. Allen,Mary Carrington,Marcus Altfeld
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The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions

Matthias Nahrendorf,Filip K. Swirski,Elena Aikawa,Lars Stangenberg,Thomas Wurdinger,Jose-Luiz Figueiredo,Peter Libby,Ralph Weissleder,Mikael J. Pittet
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Commentary

Triple bypass: complicated paths to HIV escape

Andrew J. McMichael
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Brief Definitive Report

A novel M cell–specific carbohydrate-targeted mucosal vaccine effectively induces antigen-specific immune responses

Tomonori Nochi,Yoshikazu Yuki,Akiko Matsumura,Mio Mejima,Kazutaka Terahara,Dong-Young Kim,Satoshi Fukuyama,Kiyoko Iwatsuki-Horimoto,Yoshihiro Kawaoka,Tomoko Kohda,Shunji Kozaki,Osamu Igarashi,Hiroshi Kiyono
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Mast cell deficiency in KitW-sh mice does not impair antibody-mediated arthritis

Joseph S. Zhou,Wei Xing,Daniel S. Friend,K. Frank Austen,Howard R. Katz
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Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model

Keiji Hirota,Hiroyuki Yoshitomi,Motomu Hashimoto,Shinji Maeda,Shin Teradaira,Naoshi Sugimoto,Tomoyuki Yamaguchi,Takashi Nomura,Hiromu Ito,Takashi Nakamura,Noriko Sakaguchi,Shimon Sakaguchi
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Correction

Different composition of the human and the mouse γδ T cell receptor explains different phenotypes of CD3γ and CD3δ immunodeficiencies

Gabrielle M. Siegers,Mahima Swamy,Edgar Fernández-Malavé,Susana Minguet,Sylvia Rathmann,Alberto C. Guardo,Verónica Pérez-Flores,Jose R. Regueiro,Balbino Alarcón,Paul Fisch,Wolfgang W.A. Schamel
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