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Improving survival after sepsis

Hema Bashyam
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Outgrowing IRAK-4

Hema Bashyam
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Buttoned-up vessels

Hema Bashyam
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Axon-attacking antibodies

Hema Bashyam
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T cells raise the tension

Hema Bashyam
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News Feature

Ralph Steinman: Dendritic cells bring home the Lasker

Hema Bashyam
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Commentary

If the treatment works, do we need to know why?: the promise of immunotherapy for experimental medicine

Michael R. Ehrenstein,Claudia Mauri
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The yin and yang of intestinal epithelial cells in controlling dendritic cell function

Iliyan D. Iliev,Gianluca Matteoli,Maria Rescigno
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Brief Definitive Report

Class A scavenger receptors regulate tolerance against apoptotic cells, and autoantibodies against these receptors are predictive of systemic lupus

Fredrik Wermeling,Yunying Chen,Timo Pikkarainen,Annika Scheynius,Ola Winqvist,Shozo Izui,Jeffrey V. Ravetch,Karl Tryggvason,Mikael C.I. Karlsson
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The transcription factor XBP-1 is essential for the development and survival of dendritic cells

Neal N. Iwakoshi,Marc Pypaert,Laurie H. Glimcher
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Structural basis for complement factor H–linked age-related macular degeneration

Beverly E. Prosser,Steven Johnson,Pietro Roversi,Andrew P. Herbert,Bärbel S. Blaum,Jess Tyrrell,Thomas A. Jowitt,Simon J. Clark,Edward Tarelli,Dušan Uhrín,Paul N. Barlow,Robert B. Sim,Anthony J. Day,Susan M. Lea
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Myosin IIA is required for cytolytic granule exocytosis in human NK cells

Milena M. Andzelm,Xi Chen,Konrad Krzewski,Jordan S. Orange,Jack L. Strominger
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Article

Chromosomal reinsertion of broken RSS ends during T cell development

John D. Curry,Danae Schulz,Cynthia J. Guidos,Jayne S. Danska,Lauryl Nutter,Andre Nussenzweig,Mark S. Schlissel
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Cdc42-interacting protein–4 functionally links actin and microtubule networks at the cytolytic NK cell immunological synapse

Pinaki P. Banerjee,Rahul Pandey,Rena Zheng,Megan M. Suhoski,Linda Monaco-Shawver,Jordan S. Orange
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Programmed death-1 (PD-1) defines a transient and dysfunctional oligoclonal T cell population in acute homeostatic proliferation

Sue-Jane Lin,Craig D. Peacock,Kapil Bahl,Raymond M. Welsh
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Sphingosine 1-phosphate dependence in the regulation of lymphocyte trafficking to the gut epithelium

Jun Kunisawa,Yosuke Kurashima,Morio Higuchi,Masashi Gohda,Izumi Ishikawa,Ikuko Ogahara,Namju Kim,Miki Shimizu,Hiroshi Kiyono
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Functionally specialized junctions between endothelial cells of lymphatic vessels

Peter Baluk,Jonas Fuxe,Hiroya Hashizume,Talia Romano,Erin Lashnits,Stefan Butz,Dietmar Vestweber,Monica Corada,Cinzia Molendini,Elisabetta Dejana,Donald M. McDonald
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Neurofascin as a novel target for autoantibody-mediated axonal injury

Emily K. Mathey,Tobias Derfuss,Maria K. Storch,Kieran R. Williams,Kimberly Hales,David R. Woolley,Abdulmonem Al-Hayani,Stephen N. Davies,Matthew N. Rasband,Tomas Olsson,Anja Moldenhauer,Sviataslau Velhin,Reinhard Hohlfeld,Edgar Meinl,Christopher Linington
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Reexpression of caveolin-1 in endothelium rescues the vascular, cardiac, and pulmonary defects in global caveolin-1 knockout mice

Takahisa Murata,Michelle I. Lin,Yan Huang,Jun Yu,Phillip Michael Bauer,Frank J. Giordano,William C. Sessa
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High basal STAT4 balanced by STAT1 induction to control type 1 interferon effects in natural killer cells

Takuya Miyagi,M. Pilar Gil,Xin Wang,Jennifer Louten,Wen-Ming Chu,Christine A. Biron
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The PP2A inhibitor SET regulates natural killer cell IFN-γ production

Rossana Trotta,David Ciarlariello,Jessica Dal Col,Jeffrey Allard, II,Paolo Neviani,Ramasamy Santhanam,Hsiaoyin Mao,Brian Becknell,Jianhua Yu,Amy K. Ferketich,Brittany Thomas,Aalok Modi,Bradley W. Blaser,Danilo Perrotti,Michael A. Caligiuri
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Selective predisposition to bacterial infections in IRAK-4–deficient children: IRAK-4–dependent TLRs are otherwise redundant in protective immunity

Cheng-Lung Ku,Horst von Bernuth,Capucine Picard,Shen-Ying Zhang,Huey-Hsuan Chang,Kun Yang,Maya Chrabieh,Andrew C. Issekutz,Coleen K. Cunningham,John Gallin,Steven M. Holland,Chaim Roifman,Stephan Ehl,Joanne Smart,Mimi Tang,Franck J. Barrat,Ofer Levy,Douglas McDonald,Noorbibi K. Day-Good,Richard Miller,Hidetoshi Takada,Toshiro Hara,Sami Al-Hajjar,Abdulaziz Al-Ghonaium,David Speert,Damien Sanlaville,Xiaoxia Li,Frédéric Geissmann,Eric Vivier,László Maródi,Ben-Zion Garty,Helen Chapel,Carlos Rodriguez-Gallego,Xavier Bossuyt,Laurent Abel,Anne Puel,Jean-Laurent Casanova
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Plasmacytoid dendritic cells initiate a complex chemokine and cytokine network and are a viable drug target in chronic HCV patients

In Special Collection: 2020 Nobel Prize Collection
Jérémie Decalf,Sandrine Fernandes,Randy Longman,Mina Ahloulay,Françoise Audat,François Lefrerre,Charles M. Rice,Stanislas Pol,Matthew L. Albert
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Endotoxemia and sepsis mortality reduction by non-anticoagulant–activated protein C

Edward J. Kerschen,José A. Fernandez,Brian C. Cooley,Xia V. Yang,Rashmi Sood,Laurent O. Mosnier,Francis J. Castellino,Nigel Mackman,John H. Griffin,Hartmut Weiler
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Role of the T cell in the genesis of angiotensin II–induced hypertension and vascular dysfunction

Tomasz J. Guzik,Nyssa E. Hoch,Kathryn A. Brown,Louise A. McCann,Ayaz Rahman,Sergey Dikalov,Jorg Goronzy,Cornelia Weyand,David G. Harrison
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Staphylococcal complement evasion by various convertase-blocking molecules

Ilse Jongerius,Jörg Köhl,Manoj K. Pandey,Maartje Ruyken,Kok P.M. van Kessel,Jos A.G. van Strijp,Suzan H.M. Rooijakkers
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Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover

Jorge R. Almeida,David A. Price,Laura Papagno,Zaïna Aït Arkoub,Delphine Sauce,Ethan Bornstein,Tedi E. Asher,Assia Samri,Aurélie Schnuriger,Ioannis Theodorou,Dominique Costagliola,Christine Rouzioux,Henri Agut,Anne-Geneviève Marcelin,Daniel Douek,Brigitte Autran,Victor Appay
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Correction

Sustained expansion of NKT cells and antigen-specific T cells after injection of α-galactosyl-ceramide loaded mature dendritic cells in cancer patients

David H. Chang,Keren Osman,John Connolly,Anjli Kukreja,Joseph Krasovsky,Maggi Pack,Aisha Hutchinson,Matthew Geller,Nancy Liu,Rebecca Annable,Jennifer Shay,Kelly Kirchhoff,Nobusuke Nishi,Yoshitaka Ando,Kunihiko Hayashi,Hani Hassoun,Ralph M. Steinman,Madhav V. Dhodapkar
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Selective blockade of the inhibitory Fcγ receptor (FcγRIIB) in human dendritic cells and monocytes induces a type I interferon response program

Kavita M. Dhodapkar,Devi Banerjee,John Connolly,Anjli Kukreja,Elyana Matayeva,Maria Concetta Veri,Jeffrey V. Ravetch,Ralph M. Steinman,Madhav V. Dhodapkar
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A role for AID in chromosome translocations between c-myc and the IgH variable region

Yair Dorsett,Davide F. Robbiani,Mila Jankovic,Bernardo Reina-San-Martin,Thomas R. Eisenreich,Michel C. Nussenzweig
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Progressive CD4+ central–memory T cell decline results in CD4+ effector–memory insufficiency and overt disease in chronic SIV infection

Afam Okoye,Martin Meier-Schellersheim,Jason M. Brenchley,Shoko I. Hagen,Joshua M. Walker,Mukta Rohankhedkar,Richard Lum,John B. Edgar,Shannon L. Planer,Alfred Legasse,Andrew W. Sylwester,Michael Piatak, Jr.,Jeffrey D. Lifson,Vernon C. Maino,Donald L. Sodora,Daniel C. Douek,Michael K. Axthelm,Zvi Grossman,Louis J. Picker
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Selective blockade of the inhibitory Fcγ receptor (FcγRIIB) in human dendritic cells and monocytes induces a type I interferon response program

Kavita M. Dhodapkar,Devi Banerjee,John Connolly,Anjli Kukreja,Elyana Matayeva,Maria Concetta Veri,Jeffrey V. Ravetch,Ralph M. Steinman,Madhav V. Dhodapkar
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