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Issues

Volume 203, Issue 7
10 July 2006
Issue Cover
All Issues
ISSN 0022-1007
EISSN 1540-9538

In This Issue

Finding NEMO mutations
Heather L. Van Epps
View Articletitled, Finding NEMO mutations
Dendritic cell paralysis
Heather L. Van Epps
View Articletitled, Dendritic cell paralysis
Splenic schooling dampens inflammation
Heather L. Van Epps
View Articletitled, Splenic schooling dampens inflammation
Melanomas disable DCs
Heather L. Van Epps
View Articletitled, Melanomas disable DCs
T cells get energized
Heather L. Van Epps
View Articletitled, T cells get energized

From the Archive

Kicking off adaptive immunity: the discovery of dendritic cells
Alla Katsnelson
View Articletitled, Kicking off adaptive immunity: the discovery of dendritic cells

Brief Definitive Report

Splenectomy inactivates the cholinergic antiinflammatory pathway during lethal endotoxemia and polymicrobial sepsis
Jared M. Huston,Mahendar Ochani,Mauricio Rosas-Ballina,Hong Liao,Kanta Ochani,Valentin A. Pavlov,Margot Gallowitsch-Puerta,Mala Ashok,Christopher J. Czura,Brian Foxwell,Kevin J. Tracey,Luis Ulloa
View Articletitled, Splenectomy inactivates the cholinergic antiinflammatory pathway during lethal endotoxemia and polymicrobial sepsis
Plasmacytoid dendritic cells of melanoma patients present exogenous proteins to CD4+ T cells after FcγRII-mediated uptake
Daniel Benitez-Ribas,Gosse J. Adema,Gregor Winkels,Ina S. Klasen,Cornelis J.A. Punt,Carl G. Figdor,I. Jolanda M. de Vries
View Articletitled, Plasmacytoid dendritic cells of melanoma patients present exogenous proteins to CD4<sup>+</sup> T cells after FcγRII-mediated uptake
Role of HMGB1 in apoptosis-mediated sepsis lethality
Shixin Qin,Haichao Wang,Renqi Yuan,Hui Li,Mahendar Ochani,Kanta Ochani,Mauricio Rosas-Ballina,Chris J. Czura,Jared M. Huston,Ed Miller,Xinchun Lin,Barbara Sherry,Anjali Kumar,Greg LaRosa,Walter Newman,Kevin J. Tracey,Huan Yang
View Articletitled, Role of HMGB1 in apoptosis-mediated sepsis lethality
The clone size of peripheral CD8 T cells is regulated by TCR promiscuity
Yi Hao,Nicolas Legrand,Antonio A. Freitas
View Articletitled, The clone size of peripheral CD8 T cells is regulated by TCR promiscuity
The BRAF–MAPK signaling pathway is essential for cancer-immune evasion in human melanoma cells
Hidetoshi Sumimoto,Fumie Imabayashi,Tomoko Iwata,Yutaka Kawakami
View Articletitled, The BRAF–MAPK signaling pathway is essential for cancer-immune evasion in human melanoma cells
FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal
Han You,Marc Pellegrini,Katsuya Tsuchihara,Kazuo Yamamoto,Georg Hacker,Miriam Erlacher,Andreas Villunger,Tak W. Mak
View Articletitled, FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal
Regulation of the energy sensor AMP-activated protein kinase by antigen receptor and Ca2+ in T lymphocytes
Peter Tamás,Simon A. Hawley,Rosemary G. Clarke,Kirsty J. Mustard,Kevin Green,D. Grahame Hardie,Doreen A. Cantrell
View Articletitled, Regulation of the energy sensor AMP-activated protein kinase by antigen receptor and Ca<sup>2+</sup> in T lymphocytes
ESAM supports neutrophil extravasation, activation of Rho, and VEGF-induced vascular permeability
Frank Wegmann,Björn Petri,Alexander Georg Khandoga,Christian Moser,Andrej Khandoga,Stefan Volkery,Hang Li,Ines Nasdala,Oliver Brandau,Reinhard Fässler,Stefan Butz,Fritz Krombach,Dietmar Vestweber
View Articletitled, ESAM supports neutrophil extravasation, activation of Rho, and VEGF-induced vascular permeability
An autosomal dominant major gene confers predisposition to pulmonary tuberculosis in adults
Jamila El Baghdadi,Marianna Orlova,Andrea Alter,Brigitte Ranque,Mohamed Chentoufi,Faouzia Lazrak,Moulay Idriss Archane,Jean-Laurent Casanova,Abdellah Benslimane,Erwin Schurr,Laurent Abel
View Articletitled, An autosomal dominant major gene confers predisposition to pulmonary tuberculosis in adults
A crucial role for interleukin (IL)-1 in the induction of IL-17–producing T cells that mediate autoimmune encephalomyelitis
Caroline Sutton,Corinna Brereton,Brian Keogh,Kingston H.G. Mills,Ed C. Lavelle
View Articletitled, A crucial role for interleukin (IL)-1 in the induction of IL-17–producing T cells that mediate autoimmune encephalomyelitis
Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells
Nabila Seddiki,Brigitte Santner-Nanan,Jeff Martinson,John Zaunders,Sarah Sasson,Alan Landay,Michael Solomon,Warwick Selby,Stephen I. Alexander,Ralph Nanan,Anthony Kelleher,Barbara Fazekas de St. Groth
View Articletitled, Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells

Article

CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells
Weihong Liu,Amy L. Putnam,Zhou Xu-yu,Gregory L. Szot,Michael R. Lee,Shirley Zhu,Peter A. Gottlieb,Philipp Kapranov,Thomas R. Gingeras,Barbara Fazekas de St. Groth,Carol Clayberger,David M. Soper,Steven F. Ziegler,Jeffrey A. Bluestone
View Articletitled, CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4<sup>+</sup> T reg cells
Massive and destructive T cell response to homeostatic cue in CD24-deficient lymphopenic hosts
Ou Li,Xing Chang,Huiming Zhang,Ergun Kocak,Cheng Ding,Pan Zheng,Yang Liu
View Articletitled, Massive and destructive T cell response to homeostatic cue in CD24-deficient lymphopenic hosts
Critical roles of the immunoglobulin intronic enhancers in maintaining the sequential rearrangement of IgH and Igk loci
Matthew A. Inlay,Tongxiang Lin,Heather H. Gao,Yang Xu
View Articletitled, Critical roles of the immunoglobulin intronic enhancers in maintaining the sequential rearrangement of <em>IgH</em> and <em>Igk</em> loci
Phosphoinositide-dependent kinase 1 targets protein kinase A in a pathway that regulates interleukin 4
Ajay Nirula,Mary Ho,Hyewon Phee,Jeroen Roose,Arthur Weiss
View Articletitled, Phosphoinositide-dependent kinase 1 targets protein kinase A in a pathway that regulates interleukin 4
X-linked susceptibility to mycobacteria is caused by mutations in NEMO impairing CD40-dependent IL-12 production
Orchidée Filipe-Santos,Jacinta Bustamante,Margje H. Haverkamp,Emilie Vinolo,Cheng-Lung Ku,Anne Puel,David M. Frucht,Karin Christel,Horst von Bernuth,Emmanuelle Jouanguy,Jacqueline Feinberg,Anne Durandy,Brigitte Senechal,Ariane Chapgier,Guillaume Vogt,Ludovic de Beaucoudrey,Claire Fieschi,Capucine Picard,Meriem Garfa,Jalel Chemli,Mohamed Bejaoui,Maria N. Tsolia,Necil Kutukculer,Alessandro Plebani,Luigi Notarangelo,Christine Bodemer,Frédéric Geissmann,Alain Israël,Michel Véron,Maike Knackstedt,Ridha Barbouche,Laurent Abel,Klaus Magdorf,Dominique Gendrel,Fabrice Agou,Steven M. Holland,Jean-Laurent Casanova
View Articletitled, X-linked susceptibility to mycobacteria is caused by mutations in NEMO impairing CD40-dependent IL-12 production
Light chain editing generates polyreactive antibodies in chronic graft-versus-host reaction
Esther J. Witsch,Hong Cao,Hidehiro Fukuyama,Martin Weigert
View Articletitled, Light chain editing generates polyreactive antibodies in chronic graft-versus-host reaction
Essential role of membrane cholesterol in accelerated BCR internalization and uncoupling from NF-κB in B cell clonal anergy
Mathieu Bléry,Lina Tze,Lisa A. Miosge,Jesse E. Jun,Christopher C. Goodnow
View Articletitled, Essential role of membrane cholesterol in accelerated BCR internalization and uncoupling from NF-κB in B cell clonal anergy
Igβ tyrosine residues contribute to the control of B cell receptor signaling by regulating receptor internalization
Anna Gazumyan,Amy Reichlin,Michel C. Nussenzweig
View Articletitled, Igβ tyrosine residues contribute to the control of B cell receptor signaling by regulating receptor internalization
Essential role of IPS-1 in innate immune responses against RNA viruses
Himanshu Kumar,Taro Kawai,Hiroki Kato,Shintaro Sato,Ken Takahashi,Cevayir Coban,Masahiro Yamamoto,Satoshi Uematsu,Ken J. Ishii,Osamu Takeuchi,Shizuo Akira
View Articletitled, Essential role of IPS-1 in innate immune responses against RNA viruses
Interleukin 12p40 is required for dendritic cell migration and T cell priming after Mycobacterium tuberculosis infection
Shabaana A. Khader,Santiago Partida-Sanchez,Guy Bell,Dawn M. Jelley-Gibbs,Susan Swain,John E. Pearl,Nico Ghilardi,Frederic J. deSauvage,Frances E. Lund,Andrea M. Cooper
View Articletitled, Interleukin 12p40 is required for dendritic cell migration and T cell priming after <em>Mycobacterium tuberculosis</em> infection
A major histocompatibility complex class I–dependent subset of memory phenotype CD8+ cells
Onur Boyman,Jae-Ho Cho,Joyce T. Tan,Charles D. Surh,Jonathan Sprent
View Articletitled, A major histocompatibility complex class I–dependent subset of memory phenotype CD8<sup>+</sup> cells
Of Interest in the JCB
Microclusters of inhibitory killer immunoglobulin–like receptor signaling at natural killer cell immunological synapses
Bebhinn Treanor,Peter M.P. Lanigan,Sunil Kumar,Chris Dunsby,Ian Munro,Egidijus Auksorius,Fiona J. Culley,Marco A. Purbhoo,David Phillips,Mark A.A. Neil,Deborah N. Burshtyn,Paul M.W. French,Daniel M. Davis
View Articletitled, Microclusters of inhibitory killer immunoglobulin–like receptor signaling at natural killer cell immunological synapses

Correction

Correction
Heather L. Van Epps
View Articletitled, Correction
Correction
Penelope D. Barnes,Molly A. Bergman,Joan Mecsas,Ralph R. Isberg
View Articletitled, Correction
Correction
Iannis Aifantis,Craig H. Bassing,Annette I. Garbe,Katie Sawai,Frederick W. Alt,Harald von Boehmer
View Articletitled, Correction

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Helper T cell immunity in humans with inherited CD4 deficiency
Piezo1 channels restrain ILC2s and regulate the development of airway hyperreactivity
Altering the distribution of Foxp3+ regulatory T cells results in tissue-specific inflammatory disease

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