Skip to Main Content



  • Cover Image

    Cover Image

    issue cover
    Control of infection with virulent, but not avirulent, Mycobacterium tuberculosis (Mtb) in mice requires T helper type 1 (Th1)-induced synthesis of inducible nitric oxide synthase (NOS2) by infected macrophages at sites of infection. Shown (right) are macrophages in a lung lesion of a wild-type mouse stained brown for NOS2 by immunocytochemistry, and containing acid fast virulent Mtb bacilli stained red by acid fast staining. At sites of Mtb infection in the lungs NOS2 gene-deleted mice (left) NOS2-positive macrophages are absent, and the lesions are massively populated by infected neutrophils in different stages of degeneration. See related article by Jung et al., pp. 991-998.
  • PDF Icon PDF LinkTable of Contents
  • PDF Icon PDF LinkEditorial Board
ISSN 0022-1007
EISSN 1540-9538
In this Issue



Brief Definitive Report


Close Modal
This Feature Is Available To Subscribers Only

Sign In or Create an Account

Close Modal
Close Modal