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    Section of a lung from a mouse given a protein extract of Aspergillus fumigatus intranasally three times per week is shown, with a dense inflammatory infiltrate in the connective tissue between a small vessel (right) and a bronchiole (left). The infiltrate consists predominantly of eosinophils with a smaller population of lymphocytes and macrophages. In the upper right corner, an alveolar airspace is present that contains several eosinophils, lymphocytes, and macrophages. The authors demonstrate that the seven transmembrane–spanning, G protein–coupled receptor for leukotriene B4 (LTB4) is upregulated in the lung after Aspergillus challenge. Hematoxylin and eosin staining was performed by Dr. Matt van de Rijn. See related article in this issue by Huang et al., 1063–1074.

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ISSN 0022-1007
EISSN 1540-9538
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