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Lipid Mediators in Immunity

Lipid molecules represent major structural elements of the cell as well as fuel reserves. However, lipids are also signaling molecules able to affect immune cell activity and even trigger cell death. In this special collection, we present recent JEM articles that uncover roles of lysophospholipids and other signaling lipids in immunity, from modulating B cell and T cell function to mediating pathogen recognition. We hope you will enjoy reading this collection and encourage your feedback on Twitter at @JExpMed. To learn more about JEM and to submit your research, please visit https://rupress.org/JEM or contact the editorial office. Sign up to receive future special collections here.

Image © 2021 Cotton et al.

Special Collection Image
Review
Xin Chen; Rui Kang; Guido Kroemer; Daolin Tang
DOI: 10.1084/jem.20210518
Article
Rachel N. Cotton; Marcin Wegrecki; Tan-Yun Cheng; Yi-Ling Chen; Natacha Veerapen; Jérôme Le Nours; Dennis P. Orgill; Bohdan Pomahac; Simon G. Talbot; Richard Willis; John D. Altman; Annemieke de Jong; Ildiko Van Rhijn; Rachael A. Clark; Gurdyal S. Besra; Graham Ogg; Jamie Rossjohn; D. Branch Moody
DOI: 10.1084/jem.20202699
Article
Guillaume Harlé; Camille Kowalski; Juan Dubrot; Dale Brighouse; Gaëlle Clavel; Robert Pick; Natacha Bessis; Jennifer Niven; Christoph Scheiermann; Monique Gannagé; Stéphanie Hugues
DOI: 10.1084/jem.20201776
Brief Definitive Report
Rahul Vijay; Jenna J. Guthmiller; Alexandria J. Sturtz; Sequoia Crooks; Jordan T. Johnson; Lei Li; Linda Yu-Ling Lan; Rosemary L. Pope; Yani Chen; Kai J. Rogers; Nirmal Dutta; Jason E. Toombs; Mary E. Wilson; Patrick C. Wilson; Wendy Maury; Rolf A. Brekken; Noah S. Butler
DOI: 10.1084/jem.20202359
Article
Masahiro Nagata; Kenji Toyonaga; Eri Ishikawa; Shojiro Haji; Nobuyuki Okahashi; Masatomo Takahashi; Yoshihiro Izumi; Akihiro Imamura; Koichi Takato; Hideharu Ishida; Shigenori Nagai; Petr Illarionov; Bridget L. Stocker; Mattie S.M. Timmer; Dylan G.M. Smith; Spencer J. Williams; Takeshi Bamba; Tomofumi Miyamoto; Makoto Arita; Ben J. Appelmelk; Sho Yamasaki
DOI: 10.1084/jem.20200815
Brief Definitive Report
Xingrong Du; Hu Zeng; Shaofeng Liu; Cliff Guy; Yogesh Dhungana; Geoffrey Neale; Martin O. Bergo; Hongbo Chi
DOI: 10.1084/jem.20190969
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