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Innate Immune Signaling in Disease and Homeostasis

This special collection curated by the JEM editorial team offers an overview of the role of innate immune signaling in pathogen infections, cancer, inflammatory diseases, and tissue homeostasis. The collection covers a range of innate immune signaling pathways, including inflammasome and cGAS-STING signaling. Articles featured in the collection were published within the past 12 months and have been selected based on usage, relevance, and level of discussion on social media. We hope you enjoy reading this collection, and encourage your feedback via Twitter and email. Sign up to receive future special collections here.

Image © 2020 Megli et al. 

Special Collection Image
Chunmei Ma; Sheng Li; Yingchao Hu; Yan Ma; Yuqing Wu; Chunyan Wu; Xue Liu; Bingwei Wang; Gang Hu; Jiawei Zhou; Shuo Yang
DOI: 10.1084/jem.20201796
Kaiting Yang; Yuzhu Hou; Yuan Zhang; Hua Liang; Anukriti Sharma; Wenxin Zheng; Liangliang Wang; Rolando Torres; Ken Tatebe; Steven J. Chmura; Sean P. Pitroda; Jack A. Gilbert; Yang-Xin Fu; Ralph R. Weichselbaum
DOI: 10.1084/jem.20201915
Nuo Xu; Douglas C. Palmer; Alexander C. Robeson; Peishun Shou; Hemamalini Bommiasamy; Sonia J. Laurie; Caryn Willis; Gianpietro Dotti; Benjamin G. Vincent; Nicholas P. Restifo; Jonathan S. Serody
DOI: 10.1084/jem.20200844
Tamara S. Rodrigues; Keyla S.G. de Sá; Adriene Y. Ishimoto; Amanda Becerra; Samuel Oliveira; Leticia Almeida; Augusto V. Gonçalves; Debora B. Perucello; Warrison A. Andrade; Ricardo Castro; Flavio P. Veras; Juliana E. Toller-Kawahisa; Daniele C. Nascimento; Mikhael H.F. de Lima; Camila M.S. Silva; Diego B. Caetite; Ronaldo B. Martins; Italo A. Castro; Marjorie C. Pontelli; Fabio C. de Barros; Natália B. do Amaral; Marcela C. Giannini; Letícia P. Bonjorno; Maria Isabel F. Lopes; Rodrigo C. Santana; Fernando C. Vilar; Maria Auxiliadora-Martins; Rodrigo Luppino-Assad; Sergio C.L. de Almeida; Fabiola R. de Oliveira; Sabrina S. Batah; Li Siyuan; Maira N. Benatti; Thiago M. Cunha; José C. Alves-Filho; Fernando Q. Cunha; Larissa D. Cunha; Fabiani G. Frantz; Tiana Kohlsdorf; Alexandre T. Fabro; Eurico Arruda; Renê D.R. de Oliveira; Paulo Louzada-Junior; Dario S. Zamboni
DOI: 10.1084/jem.20201707
Christina Megli; Stefanie Morosky; Dhivyaa Rajasundaram; Carolyn B. Coyne
DOI: 10.1084/jem.20200649
Zimu Deng; Zhenlu Chong; Christopher S. Law; Kojiro Mukai; Frances O. Ho; Tereza Martinu; Bradley J. Backes; Walter L. Eckalbar; Tomohiko Taguchi; Anthony K. Shum
DOI: 10.1084/jem.20201045
Alice Lepelley; Maria José Martin-Niclós; Melvin Le Bihan; Joseph A. Marsh; Carolina Uggenti; Gillian I. Rice; Vincent Bondet; Darragh Duffy; Jonny Hertzog; Jan Rehwinkel; Serge Amselem; Siham Boulisfane-El Khalifi; Mary Brennan; Edwin Carter; Lucienne Chatenoud; Stéphanie Chhun; Aurore Coulomb l’Hermine; Marine Depp; Marie Legendre; Karen J. Mackenzie; Jonathan Marey; Catherine McDougall; Kathryn J. McKenzie; Thierry Jo Molina; Bénédicte Neven; Luis Seabra; Caroline Thumerelle; Marie Wislez; Nadia Nathan; Nicolas Manel; Yanick J. Crow; Marie-Louise Frémond
DOI: 10.1084/jem.20200600
Chiranjeevi Bodda; Line S. Reinert; Stefanie Fruhwürth; Timmy Richardo; Chenglong Sun; Bao-cun Zhang; Maria Kalamvoki; Anja Pohlmann; Trine H. Mogensen; Petra Bergström; Lotta Agholme; Peter O’Hare; Beate Sodeik; Mads Gyrd-Hansen; Henrik Zetterberg; Søren R. Paludan
DOI: 10.1084/jem.20191422
Jeannette L. Tenthorey; Roberto A. Chavez; Thornton W. Thompson; Katherine A. Deets; Russell E. Vance; Isabella Rauch
DOI: 10.1084/jem.20191736
Yaoyao Shi; Wenxin Zheng; Kaiting Yang; Katharine G. Harris; Kaiyuan Ni; Lai Xue; Wenbin Lin; Eugene B. Chang; Ralph R. Weichselbaum; Yang-Xin Fu
DOI: 10.1084/jem.20192282
R.K. Subbarao Malireddi; Prajwal Gurung; Sannula Kesavardhana; Parimal Samir; Amanda Burton; Harisankeerth Mummareddy; Peter Vogel; Stephane Pelletier; Sandeepta Burgula; Thirumala-Devi Kanneganti
DOI: 10.1084/jem.20191644
Amy H. Chan; Kate Schroder
DOI: 10.1084/jem.20190314
Pontus Orning; Egil Lien; Katherine A. Fitzgerald
DOI: 10.1084/jem.20190545
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