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Volume 95, Issue 5
1 May 1952
Journal of Experimental Medicine Cover Image for Volume 95, Issue 5
Article| May 01 1952

AN ELECTROPHORETIC STUDY OF URINARY PROTEIN IN THE RAT

Alvin L. Sellers,
Alvin L. Sellers
From the Institute for Medical Research, Cedars of Lebanon Hospital, Department of Medicine, University of Southern California School of Medicine, and the Department of Physiological Chemistry, School of Medicine, University of California at Los Angeles
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Sidney Roberts,
Sidney Roberts
From the Institute for Medical Research, Cedars of Lebanon Hospital, Department of Medicine, University of Southern California School of Medicine, and the Department of Physiological Chemistry, School of Medicine, University of California at Los Angeles
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Irene Rask,
Irene Rask
From the Institute for Medical Research, Cedars of Lebanon Hospital, Department of Medicine, University of Southern California School of Medicine, and the Department of Physiological Chemistry, School of Medicine, University of California at Los Angeles
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Stephen Smith, 3rd,
Stephen Smith, 3rd
From the Institute for Medical Research, Cedars of Lebanon Hospital, Department of Medicine, University of Southern California School of Medicine, and the Department of Physiological Chemistry, School of Medicine, University of California at Los Angeles
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Jessie Marmorston,
Jessie Marmorston
From the Institute for Medical Research, Cedars of Lebanon Hospital, Department of Medicine, University of Southern California School of Medicine, and the Department of Physiological Chemistry, School of Medicine, University of California at Los Angeles
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Howard C. Goodman
Howard C. Goodman
From the Institute for Medical Research, Cedars of Lebanon Hospital, Department of Medicine, University of Southern California School of Medicine, and the Department of Physiological Chemistry, School of Medicine, University of California at Los Angeles
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Author and Article Information
Alvin L. Sellers
From the Institute for Medical Research, Cedars of Lebanon Hospital, Department of Medicine, University of Southern California School of Medicine, and the Department of Physiological Chemistry, School of Medicine, University of California at Los Angeles
Sidney Roberts
From the Institute for Medical Research, Cedars of Lebanon Hospital, Department of Medicine, University of Southern California School of Medicine, and the Department of Physiological Chemistry, School of Medicine, University of California at Los Angeles
Irene Rask
From the Institute for Medical Research, Cedars of Lebanon Hospital, Department of Medicine, University of Southern California School of Medicine, and the Department of Physiological Chemistry, School of Medicine, University of California at Los Angeles
Stephen Smith, 3rd
From the Institute for Medical Research, Cedars of Lebanon Hospital, Department of Medicine, University of Southern California School of Medicine, and the Department of Physiological Chemistry, School of Medicine, University of California at Los Angeles
Jessie Marmorston
From the Institute for Medical Research, Cedars of Lebanon Hospital, Department of Medicine, University of Southern California School of Medicine, and the Department of Physiological Chemistry, School of Medicine, University of California at Los Angeles
Howard C. Goodman
From the Institute for Medical Research, Cedars of Lebanon Hospital, Department of Medicine, University of Southern California School of Medicine, and the Department of Physiological Chemistry, School of Medicine, University of California at Los Angeles
Received: January 29 1952
Online ISSN: 1540-9538
Print ISSN: 0022-1007
Copyright, 1952, by The Rockefeller Institute for Medical Research New York
1952
J Exp Med (1952) 95 (5): 465–472.
https://doi.org/10.1084/jem.95.5.465
Article history
Received:
January 29 1952

The nature of the proteins present in the urine of the normal rat has been investigated by electrophoretic analysis and by fractional precipitation of these proteins by ammonium sulfate. Components similar to serum α- and ß-globulin constitute the major portion of the urinary protein in both male and female rats.

Following the intraperitoneal injection of renin, a massive proteinuria occurs. The proteins excreted are similar in proportion and electric mobility to those of normal rat serum.

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Copyright, 1952, by The Rockefeller Institute for Medical Research New York
1952
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