At the onset of an epidemic in a closed institution about one-fourth of the inmates were skin-tested. During the year following the skin test, 5 cases of hepatitis with jaundice were recorded among 320 skin-tested individuals with unknown histories, one in the 144 skin test-positive, and 4 in the 176 skin test-negative subjects. In contrast 112 cases occurred among the 825 non-skin-tested individuals. Thus, the incidence of jaundice in the skin-tested group was 1.6 per cent as against 13.6 per cent in the non-skin-tested individuals. Possible explanations for this observation have been discussed.
STUDIES ON THE AGENT OF INFECTIOUS HEPATITIS : III. THE EFFECT OF SKIN TESTS FOR INFECTIOUS HEPATITIS ON THE INCIDENCE OF THE DISEASE IN A CLOSED INSTITUTION
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Miles E. Drake, Charles Ward, Joseph Stokes, Werner Henle, George C. Medairy, Françoise Mangold, Gertrude Henle; STUDIES ON THE AGENT OF INFECTIOUS HEPATITIS : III. THE EFFECT OF SKIN TESTS FOR INFECTIOUS HEPATITIS ON THE INCIDENCE OF THE DISEASE IN A CLOSED INSTITUTION . J Exp Med 1 March 1952; 95 (3): 231–239. doi: https://doi.org/10.1084/jem.95.3.231
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