RENIN PROTEINURIA IN THE RAT : II. EVIDENCE THAT RENIN DOES NOT INTERFERE WITH THE TUBULAR RESORPTION OF PURIFIED HUMAN HEMOGLOBIN OR BOVINE ALBUMIN

The intraperitoneal injection of renin together with purified human hemoglobin or bovine albumin increases the weight of the kidneys and increases the number of athrocytosed particles of protein in the cells of the proximal convoluted tubules. In the case of bovine albumin administration there is a threefold increase in protein excretion in those rats given renin as compared with those given bovine albumin alone. A possible explanation of these effects is given.