The ability to carry out with some measure of precision mouse protection tests for the estimation of potency of antipneumococcus sera has made possible the correlation of the protective potency with the amount of specifically precipitable protein. With antipneumococcus rabbit sera these protective ratios are relatively constant and higher than those with immune horse serum. Type I antipneumococcus horse sera, on the other hand, show no such constancy but fall into two groups; and there is as yet no simple method for determining to which group a serum belongs.
PROPERTIES OF THE TYPE SPECIFIC PROTEINS OF ANTIPNEUMOCOCCUS SERA : I. THE MOUSE PROTECTIVE VALUE OF TYPE I SERA WITH REFERENCE TO THE PRECIPITIN CONTENT
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Kenneth Goodner, Frank L. Horsfall; PROPERTIES OF THE TYPE SPECIFIC PROTEINS OF ANTIPNEUMOCOCCUS SERA : I. THE MOUSE PROTECTIVE VALUE OF TYPE I SERA WITH REFERENCE TO THE PRECIPITIN CONTENT . J Exp Med 1 October 1937; 66 (4): 413–424. doi: https://doi.org/10.1084/jem.66.4.413
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