1. Experiments are presented demonstrating specific inhibition of phage by soluble products of bacteria.

2. The inhibition proceeds more rapidly when the phage and bacterial extracts are incubated at 37° than at ice box temperature.

3. The specificity of the reaction in the instances studied is probably connected with the presence of specific soluble carbohydrates.

4. A reaction is available for the study of the chemistry of bacillary antigens in terms of bacteriophage.

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