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1. When the plasma protein of dogs is lowered by plasmapheresis, the concentration of chloride and sodium in the plasma and the cerebrospinal fluid tends to become the same, a diminishing of the usual disparity which exists in the presence of a normal plasma protein.

2. This is in accord with the theory that the cerebrospinal fluid is a dialysate, with the choroid plexus acting as a simple dialyzing membrane.

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