The relation between a strain of B. coli and its mutant with reference to the production of agglutinins and protective antibodies may be expressed by the statement that the original strain when injected into cows develops antibodies both towards itself and the mutant whereas the mutant produces them only towards itself. The results point to the capsular substance as the material carrying virulence or, expressed somewhat differently, the factor which protects the microorganism in the host.
Article| September 01 1928
THE RELATION OF THE CAPSULAR SUBSTANCE OF B. COLI TO ANTIBODY PRODUCTION
From the Department of Animal Pathology of The Rockefeller Institute for Medical Research, Princeton, N. J.
Received: June 04 1928
Online Issn: 1540-9538
Print Issn: 0022-1007
Copyright, 1928, by The Rockefeller Institute for Medical Research New York
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Theobald Smith; THE RELATION OF THE CAPSULAR SUBSTANCE OF B. COLI TO ANTIBODY PRODUCTION . J Exp Med 1 September 1928; 48 (3): 351–361. doi: https://doi.org/10.1084/jem.48.3.351
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