EXPERIMENTAL RICKETS IN RATS VI. THE ANATOMICAL CHANGES WHICH ACCOMPANY HEALING OF EXPERIMENTAL RAT RICKETS, UNDER THE INFLUENCE OF COD LIVER OIL OR ITS ACTIVE DERIVATIVES.

Pappenheimer , Alwin M.

doi:10.1084/jem.36.3.335

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Article| September 01 1922

EXPERIMENTAL RICKETS IN RATS : VI. THE ANATOMICAL CHANGES WHICH ACCOMPANY HEALING OF EXPERIMENTAL RAT RICKETS, UNDER THE INFLUENCE OF COD LIVER OIL OR ITS ACTIVE DERIVATIVES.

Alwin M. Pappenheimer

From the Department of Pathology of the College of Physicians and Surgeons, Columbia University, New York.

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Author and Article Information

Alwin M. Pappenheimer

From the Department of Pathology of the College of Physicians and Surgeons, Columbia University, New York.

Received: May 07 1922

Online ISSN: 1540-9538

Print ISSN: 0022-1007

Copyright, 1922, by The Rockefeller Institute for Medical Research New York

1922

J Exp Med (1922) 36 (3): 335–355.

https://doi.org/10.1084/jem.36.3.335

Rats which had developed rickets were treated with cod liver oil or an active fraction of cod liver oil, and the various changes which occur in the healing of the bone lesions were studied. Several phases are described, from the early deposit of calcium salts in the zone of preparatory calcification to the return to normal bone.

These stages correspond closely to those found in the healing of human rickets.

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Copyright, 1922, by The Rockefeller Institute for Medical Research New York

1922

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EXPERIMENTAL RICKETS IN RATS : VI. THE ANATOMICAL CHANGES WHICH ACCOMPANY HEALING OF EXPERIMENTAL RAT RICKETS, UNDER THE INFLUENCE OF COD LIVER OIL OR ITS ACTIVE DERIVATIVES.

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