Vol. 203, No. 1, January 23, 2006. Pages 99-110.

Please note that an error appeared in the online early release version of this article. The final html, pdf, and print versions have been corrected. For reference, the correction appears below.

All data in the bottom row of Table II should have been shifted one column to the right. The corrected table appears below.

Table II.

Mutations in VH3-23-Cγ transcripts from PBL from ATRD patients and controlsa

Clones
Mutations in V region
Clustering ratio
R/S
Age (yr)
All
Distinct
Unmutated
Total
% bp
CDR/FRb
CDRs
FRs
ATRD patients          
    ATRD1 25 15 13 0 302 8.6 0.73 3.4 1.8 
    ATRD2 13 15 14 2 258 6.8 0.73 3.7 1.7 
    ATRD3 15 6 6 0 194 11.9 0.62 3.9 2.0 
    Total  36 33 2 754 8.4 0.70 3.6 1.8 
Controls          
    C1 14 12 11 1 100 3.4 1.22 5.9 1.5 
    C2 adult 11 11 0 275 9.3 0.73 4.5 1.7 
    C3 28 6 6 0 147 9.0 0.69 5.7 2.0 
    C4 24 8 8 0 178 8.2 0.51 14.0 2.2 
    C5 30 4 4 0 49 4.5 0.53 c 1.1 
    Total
 
 		41
 		40
 		1
 		749
 		6.9
 		0.70
 		6.2
 		1.8
 
Clones
Mutations in V region
Clustering ratio
R/S
Age (yr)
All
Distinct
Unmutated
Total
% bp
CDR/FRb
CDRs
FRs
ATRD patients          
    ATRD1 25 15 13 0 302 8.6 0.73 3.4 1.8 
    ATRD2 13 15 14 2 258 6.8 0.73 3.7 1.7 
    ATRD3 15 6 6 0 194 11.9 0.62 3.9 2.0 
    Total  36 33 2 754 8.4 0.70 3.6 1.8 
Controls          
    C1 14 12 11 1 100 3.4 1.22 5.9 1.5 
    C2 adult 11 11 0 275 9.3 0.73 4.5 1.7 
    C3 28 6 6 0 147 9.0 0.69 5.7 2.0 
    C4 24 8 8 0 178 8.2 0.51 14.0 2.2 
    C5 30 4 4 0 49 4.5 0.53 c 1.1 
    Total
 
 		41
 		40
 		1
 		749
 		6.9
 		0.70
 		6.2
 		1.8
 
a

Total RNA was prepared from PBL from all the patients and controls, except for donor C2; buffycoat was obtained and CD27 positive B cells were used.

b

FR, framework region.

c

Too few mutations to give a reliable ratio.

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The Rockefeller University Press
2006