The experiments show that intrabronchial insufflation of a culture of virulent pneumococcus killed by heat and still containing stainable organisms produces an inextensive, mild, patchy, superficial inflammation of the lung tissue bearing no similarity to the lesions produced by the living pneumococcus, and that insufflation of sterile bouillon causes a pronounced congestion of the lung tissue with which it comes in contact, sometimes lasting for forty-eight hours.
THE REACTION OF THE LUNGS TO THE INTRABRONCHIAL INSUFFLATION OF KILLED VIRULENT PNEUMOCOCCI AND OF PLAIN STERILE BOUILLON
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Martha Wollstein, S. J. Meltzer; THE REACTION OF THE LUNGS TO THE INTRABRONCHIAL INSUFFLATION OF KILLED VIRULENT PNEUMOCOCCI AND OF PLAIN STERILE BOUILLON . J Exp Med 1 April 1913; 17 (4): 424–428. doi: https://doi.org/10.1084/jem.17.4.424
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