The ultrastructure of the experimental encephalopathy caused by Mycoplasma neurolyticum toxin has been studied. The primary changes are (a) massive distention of astrocytes by fluid, associated with degenerative changes in these cells, (b) mechanical displacement and compression of myelinated axons by swollen astrocytic processes, (c) the appearance of free, extracellular fluid in the white matter, and (d) early primary myelin degeneration without damage to axons.
STUDIES OF PPLO INFECTION : III. ELECTRON MICROSCOPIC STUDY OF BRAIN LESIONS CAUSED BY MYCOPLASMA NEUROLYTICUM TOXIN
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Fernando Aleu, Lewis Thomas; STUDIES OF PPLO INFECTION : III. ELECTRON MICROSCOPIC STUDY OF BRAIN LESIONS CAUSED BY MYCOPLASMA NEUROLYTICUM TOXIN . J Exp Med 1 December 1966; 124 (6): 1083–1088. doi: https://doi.org/10.1084/jem.124.6.1083
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