STUDIES ON ANTIBODY PRODUCTION XI. VARIATION IN THE SECONDARY RESPONSE AS A FUNCTION OF THE LENGTH OF THE INTERVAL BETWEEN TWO ANTIGENIC STIMULI

Fecsik , Alfonz I.; Butler , William T.; Coons , Albert H.

doi:10.1084/jem.120.6.1041

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Article| December 01 1964

STUDIES ON ANTIBODY PRODUCTION : XI. VARIATION IN THE SECONDARY RESPONSE AS A FUNCTION OF THE LENGTH OF THE INTERVAL BETWEEN TWO ANTIGENIC STIMULI

Alfonz I. Fecsik,

Alfonz I. Fecsik

From the Department of Bacteriology and Immunology, Harvard Medical School, Boston

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William T. Butler,

William T. Butler

From the Department of Bacteriology and Immunology, Harvard Medical School, Boston

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Albert H. Coons

From the Department of Bacteriology and Immunology, Harvard Medical School, Boston

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Author and Article Information

Alfonz I. Fecsik

From the Department of Bacteriology and Immunology, Harvard Medical School, Boston

William T. Butler

From the Department of Bacteriology and Immunology, Harvard Medical School, Boston

Albert H. Coons

From the Department of Bacteriology and Immunology, Harvard Medical School, Boston

Received: July 27 1964

Online ISSN: 1540-9538

Print ISSN: 0022-1007

1964

J Exp Med (1964) 120 (6): 1041–1049.

https://doi.org/10.1084/jem.120.6.1041

As the interval between two antigenic stimuli to mice is lengthened, the magnitude of the response to the second dose increases up to approximately 40 days; thereafter it remains at a fairly constant, high level.

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STUDIES ON ANTIBODY PRODUCTION : XI. VARIATION IN THE SECONDARY RESPONSE AS A FUNCTION OF THE LENGTH OF THE INTERVAL BETWEEN TWO ANTIGENIC STIMULI

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