The development of tuberculin hypersensitivity in guinea pigs after BCG stimulation was suppressed by intramuscular administration of 50 mg/kg/day of 6-mercaptopurine started at the time of stimulation. Fasting of guinea pigs after BCG stimulation had no effect on the development of tuberculin hypersensitivity.
THE EFFECT OF 6-MERCAPTOPURINE ON DELAYED HYPERSENSITIVITY IN GUINEA PIGS
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John R. Hoyer, Leon W. Hoyer, Robert A. Good, Richard M. Condie; THE EFFECT OF 6-MERCAPTOPURINE ON DELAYED HYPERSENSITIVITY IN GUINEA PIGS . J Exp Med 1 November 1962; 116 (5): 679–685. doi: https://doi.org/10.1084/jem.116.5.679
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